FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts [0.03%]
简单骨囊肿中存在大量的FUS-NFATC2或EWSR1-NFATC2融合基因
Jože Pižem,Daja Šekoranja,Andrej Zupan et al.
Jože Pižem et al.
A simple bone cyst (SBC) is a benign bone lesion of unknown etiology. It can be differentiated from an aneurysmal bone cyst (ABC) by radiologic and histopathologic features, as well as by the absence of fusions of the USP6 gene characterist...
High-grade B-Cell Lymphoma With MYC, BCL2, and/or BCL6 Translocations/Rearrangements: Clinicopathologic Features of 51 Cases in a Single Institution of South China [0.03%]
伴有MYC、BCL2和(或)BCL6易位/重排的高级别B细胞淋巴瘤:中国南方某一机构中51例临床病理特征分析
Jijun Zhang,Zeping Weng,Yuhua Huang et al.
Jijun Zhang et al.
Double-hit/triple-hit lymphomas (DH/THLs) are high-grade B-cell lymphomas with MYC and BCL2 rearrangements and/or BCL6 rearrangements, which have poor outcomes after standard chemoimmunotherapy. This retrospective study analyzed 51 patients...
Jennifer Y Wang,Kelsey E Hirotsu,Tatiana M Neal et al.
Jennifer Y Wang et al.
Rash is one of the most common adverse events observed with mogamulizumab, an anti-C-C chemokine receptor 4 monoclonal antibody approved for previously treated mycosis fungoides (MF) and Sezary syndrome (SS). Given the nonspecific clinical ...
Daniel Grosser,Andres Matoso,Jonathan I Epstein
Daniel Grosser
Clear cell adenocarcinoma (CCA) is a rare tumor in the genitourinary tract with female predominance and few reports in men. We identified 15 cases of CCA in men evaluated at our institution. Five arose in the bladder, 7 in the prostate or p...
Specific Biomarker Expression Patterns in the Diagnosis of Residual and Recurrent Endometrial Precancers After Progestin Treatment: A Longitudinal Study [0.03%]
孕激素治疗后残留和复发性子宫内膜前癌的特异性生物标志物表达模式诊断:纵向研究
Hao Chen,Elena Lucas,Amanda L Strickland et al.
Hao Chen et al.
Background: Conservative management with progestin is a treatment option for atypical hyperplasia (AH). However, pathologic diagnosis of residual/recurrent lesions is often problematic because of the profound morphologic ...
Urothelial Carcinomas With Trophoblastic Differentiation, Including Choriocarcinoma: Clinicopathologic Series of 16 Cases [0.03%]
具有滋养层分化的尿路上皮癌,包括绒毛膜癌:16例临床病理系列
Christopher G Przybycin,Jesse K McKenney,Jane K Nguyen et al.
Christopher G Przybycin et al.
Trophoblastic differentiation (including choriocarcinoma) arising in urothelial carcinoma has been described in numerous case reports, but never in a single series. We present a series of these tumors, describing the morphologic spectrum, a...
Reproducibility of AJCC Criteria for Classifying Deeply Invasive Colon Cancers Is Suboptimal for Consistent Cancer Staging [0.03%]
AJCC对深部浸润性结肠癌分类标准的可重复性较差难以进行一致性的癌症分期
Nicole C Panarelli,Suntrea T G Hammer,Jingmei Lin et al.
Nicole C Panarelli et al.
The eighth edition of the American Joint Committee on Cancer (AJCC) Staging Manual attempts to address ambiguity in the pT category assignment for colon cancer from prior editions. Despite modifications, the distinction between the pT3 and ...
Claudin-18 as a Marker for Identifying the Stomach and Pancreatobiliary Tract as the Primary Sites of Metastatic Adenocarcinoma [0.03%]
Claudin-18 作为识别转移性腺癌原发部位(胃和胰胆管)的标志物
Wan-Ting Li,Yung-Ming Jeng,Ching-Yao Yang
Wan-Ting Li
Identification of the primary site of cancer is essential for the treatment of patients with cancer. Numerous immunohistochemical markers have been developed to determine the differentiation of tumor cells and suggest possible primary sites...
Amyloid-like Fibronectin Deposits in the Liver: A Novel Morphologic Finding [0.03%]
肝中类似淀粉样纤维蛋白的沉积:一个新的形态学发现
Saba Yasir,Karen L Rech,Zongming Eric Chen et al.
Saba Yasir et al.
Amyloid deposits in the liver are recognized by their hematoxylin and eosin (H&E) findings, consisting of acellular eosinophilic deposits in various compartments of the liver parenchyma, including the stroma, vessels, and rarely the hepatoc...
NF2 Tumor Suppressor Gene Inactivation in Advanced Papillary Renal Cell Carcinoma [0.03%]
晚期乳头状肾细胞癌中NF2抑癌基因的失活
Evgeny Yakirevich,Dean C Pavlick,Carmen M Perrino et al.
Evgeny Yakirevich et al.