Extrapancreatic Gastrointestinal Tract Grade 3 Well-Differentiated Neuroendocrine Tumors Behave Aggressively Compared With Lower-Grade Tumors Despite Similar Morphology [0.03%]
与低级别肿瘤具有相似形态的胃肠道三级分化良好的神经内分泌肿瘤表现出更为激进的行为方式,尽管其起源于胰腺以外地区
Monika Vyas,Andrew M Bellizzi,Kelsey McHugh et al.
Monika Vyas et al.
The WHO 2019 classification of digestive tract tumors introduced a high-grade (G3) category for well-differentiated neuroendocrine tumors (NETs). These neoplasms appear to have a better prognosis than poorly differentiated neuroendocrine ca...
Metatypic Carcinoma of the Pancreas: Delineation of a Clinicopathologically Distinct Entity, Characterized by Centrally Necrotic Demarcated High-Grade Carcinoma With Divergent Patterns, Basal Immunophenotype, and Altered Molecular Profile [0.03%]
以中央坏死为特征的元类型胰腺癌:一种具有多变形态学模式、基底免疫表型和分子改变的临床病理实体
Duygu Atasoy,Burcu Saka,Ayse Armutlu et al.
Duygu Atasoy et al.
A distinct type of pancreatic carcinoma (n=31; 6% of adenocarcinomas) is described, distinguished from conventional pancreatic ductal adenocarcinoma (PDAC) by: (1) solid/undifferentiated (sheet-like, stroma-poor) carcinomas lacking features...
Primary Pulmonary Ameloblastoma: First Case Series With Clinicopathologic and Genomic Analysis [0.03%]
原发性肺牙源性腺样瘤:临床病理及基因组分析首例系列报告
Jason C Chang,Omid Savari,Najd Alshamlan et al.
Jason C Chang et al.
Ameloblastomas are locally aggressive odontogenic tumors that most commonly arise in the mandible and maxilla and often harbor BRAF V600E mutations. While rare extragnathic ameloblastomas have been reported, primary pulmonary cases have not...
Primary Cutaneous SWI/SNF-Deficient Carcinomas: Morphologic, Immunohistochemical, and Molecular Analysis of Seven Cases [0.03%]
皮肤SWI/SNF染色体重塑复合体突变型癌的形态学、免疫组化和分子特征分析:七例报告
Shira Ronen,Julien Masliah-Planchon,Kristof Cokelaere et al.
Shira Ronen et al.
Mutations in genes encoding proteins of the SWI/SNF complex are highly recurrent in select tumor entities. Among primary cutaneous tumors, only 4 SMARCA4-deficient undifferentiated neoplasms and 3 primary cutaneous SMARCB1-deficient carcino...
GATA3 Is Underexpressed in Penile Neoplasia: Potential Implications in Diagnosis and Pathogenesis [0.03%]
GATA3在阴茎肿瘤中的低表达及其在诊断和发病机制中的潜在作用
Namratha Adiyeri Knadiyil,Antonio L Cubilla,Delia F Tifrea et al.
Namratha Adiyeri Knadiyil et al.
Penile squamous cell carcinoma (PSCC) and its established precursor, penile intraepithelial neoplasia (PeIN), are classified as HPV-associated and HPV-independent. However, there is a spectrum of precursor lesions, which presents diagnostic...
Atypical Vulvovaginal Postradiation Vascular Lesion: A Distinctive, Benign Mimic of Angiosarcoma Characterized in a Series of 15 Patients [0.03%]
非典型放射性外阴阴道血管病变:一组15例患者的良性血管瘤性疾病特征及与血管肉瘤鉴別诊断
Alexander J Neil,Yvonne Y Li,David J Papke Jr et al.
Alexander J Neil et al.
Cancers of the endometrium, cervix, and anus are frequently treated with radiation therapy (RT), which carries a risk for secondary malignancies. RT causes vaginal atrophy, dryness, and increased mucosal friability, predisposing to ulcers. ...
Perihilar Intraductal Papillary Neoplasm of the Bile Ducts: A Clinicopathologic and Molecular Genetic Study of 27 Cases [0.03%]
胆管皮质内乳头状瘤的临床病理及分子遗传学研究(27例肝门胆管为主的IPNB)
Ahmad Alkashash,Azadeh Samiei,Shaomin Hu et al.
Ahmad Alkashash et al.
The College of American Pathologists recognizes "intraductal papillary neoplasm of the bile ducts (IPNB) with an associated invasive carcinoma" in its protocols for the pancreas and intrahepatic bile ducts, but not for the perihilar or dist...
Pathologic Assessment of Retroperitoneal Sarcomas: A Position Paper By the Transatlantic Australasian Retroperitoneal Sarcoma Working Group [0.03%]
腹膜后肉瘤的病理评估——一项泛大西洋暨澳新腹膜后肉瘤工作组立场文件
Bibianna Purgina,Elena Di Blasi,Paola Collini et al.
Bibianna Purgina et al.
Most primary retroperitoneal soft tissue tumors are malignant, with liposarcomas and leiomyosarcomas being the most common. However, other sarcomas and benign tumors can also occur in this location. Pathologic evaluation of retroperitoneal ...
Composite Wilms Tumor and Renal Cell Carcinoma: A Comprehensive Clinicopathologic, Immunohistochemical, and Molecular Study of 18 Tumors Highlighting an Uncommon Pediatric Renal Entity [0.03%]
复合性肾母细胞瘤和肾细胞癌:18例肿瘤的综合临床病理、免疫组化和分子研究,重点关注一种罕见的儿科肾脏实体病变
Gordan M Vujanić,Vera A Paulson,Laura Galluzzo et al.
Gordan M Vujanić et al.
We report the largest series of 18 cases of an uncommon composite renal tumor comprised of Wilms tumor (WT) and renal cell carcinoma (RCC). The tumors were identified by rereviewing WT with "unusual" epithelial components. The age at presen...
Intra-Articular and Juxta-Articular Lipomas of the Knee: Clinicopathologic Analysis of 18 Cases Highlighting Frequent Herniation and Characteristic Histology [0.03%]
膝关节滑膜脂肪瘤和关节周围脂肪瘤的临床病理分析:18例报告着重于滑出及特征性组织学表现
Hirokazu Sugino,Mototaka Miyake,Eisuke Kobayashi et al.
Hirokazu Sugino et al.
True lipomas involving the joints are rare. In this study, we investigated 18 intra-articular and juxta-articular lipomas of the knee. The tumor occurred in middle-aged or older patients (median age: 63 years) with a strong female predilect...