"Early" Clear Cell Proliferations (Clear Cell Carcinoma in Situ) in Ovarian Endometriotic Cysts: Report of a Case Series With Recommendations for Terminology [0.03%]
卵巢子宫内膜异位囊肿中的“早期内膜样透明细胞增生（原位透明细胞癌）：一组病例报告并提出命名建议
Nesa S Karunadhas,Mark Catherwood,Helen Stringfellow et al.
Nesa S Karunadhas et al.
Clear cell carcinoma (CCC) is an uncommon malignancy accounting for ∼12% of ovarian carcinomas. Most cases arise from endometriosis, frequently an endometriotic cyst. We report a series of 6 cases where clear cell proliferations, morpholog...
Clinically Sporadic Folliculin-mutated Renal Epithelial Neoplasms Represent a Mixture of True Somatic Folliculin-mutated and Occult Birt-Hogg-Dubé Syndrome-associated Cases: Morphologic and Molecular Overlap With TSC/MTOR-mutated Eosinophilic Renal Neoplasms and MiT Family Translocation Renal Cell Carcinoma [0.03%]
临床偶发的FLCN突变肾上皮肿瘤是散发性体细胞突变型和 occult BHD综合征相关型的混合：与TSC/MTOR突变嗜酸细胞肾肿瘤及MiT家系易位肾癌在形态学和分子上的重叠
Pedram Argani,Ezra Baraban,Oksana Yaskiv et al.
Pedram Argani et al.
Germline mutations in the folliculin (FLCN) gene define Birt-Hogg-Dubé syndrome, which is associated with a variety of renal neoplasms; however, the role of FLCN mutations in sporadic renal neoplasms has not been well-defined. We identifie...
Confocal Laser Microscopy for Intraoperative Margin Assessment in Breast-Conserving Surgery: A New Procedure in the Pathology Laboratory Workflow [0.03%]
用于乳房保留手术术中切缘评估的共聚焦激光显微镜：病理实验室工作流程中的新程序
Julien Colard-Thomas,Antonia Pialoux-Guibal,Pierre Gemival et al.
Julien Colard-Thomas et al.
One of the breast-conserving surgery goals is to achieve negative resection margins and avoid reoperation. Therefore, accurate intraoperative margin assessment is essential, but still challenging. Recently, confocal microscopy devices, such...
Clinicopathologic and Genomic Analysis of Uterine Serous Carcinomas Arising From Endometrial Hyperplasia [0.03%]
子宫内膜增生起源的子宫浆液性癌的临床病理及基因组分析
Tiffany Y Sia,Douglas H R Allison,Arnaud Da Cruz Paula et al.
Tiffany Y Sia et al.
Uterine serous carcinoma (USC) typically arises from atrophic endometrium but may be associated with hyperplasia in 5% to 10% of cases. We sought to identify USC with concurrent hyperplasia and (i) define if these are clonally related, and ...
The Extensive Case Series of 21 CIC::DUX4, 18 BCOR::CCNB3 and 148 Ewing's Sarcomas From a Single Center [0.03%]
单中心报告的21例CIC::DUX4、18例BCOR::CCNB3和148例尤因肉瘤病例系列
Sirma Çetin,Gökçen Ünverengil,İsmail Yilmaz et al.
Sirma Çetin et al.
In this study, we aimed to reclassify "round cell sarcomas" identified in the Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, between 2013 and 2023, using an immunohistochemical panel including CD99, NKX2.2, ETV4...
Renal Epithelioid Angiomyolipoma: Prognostic Implications of Targeted Immunohistochemical and Molecular Markers in Conjunction with Clinicopathologic Features [0.03%]
肾上皮样血管平滑肌脂肪瘤：免疫组化及分子标记物与临床病理特征结合的预后意义
Ankur R Sangoi,Anandi Lobo,Shilpy Jha et al.
Ankur R Sangoi et al.
Epithelioid angiomyolipoma (eAML) is an uncommon subtype of angiomyolipoma, a subset of which can demonstrate malignant behavior. While some studies have proposed histopathologic features predictive of aggressive behavior in eAML, there is ...
Response to Expanding Insights Into PRAME Expression in Merkel Cell Carcinoma [0.03%]
关于Merkel细胞癌中PRAME表达的进一步见解的回应
Shyam S Raghavan
Shyam S Raghavan
Elisabeth Schlögl,Helga Hürner-Unterberger,Ingrid Simonitsch-Klupp et al.
Elisabeth Schlögl et al.
Juvenile Xanthogranuloma (JXG) is a rare form of non-Langerhans cell histiocytosis. The most common known gene mutations affect the mitogen-activated protein (MAP) kinase, phosphoinositide 3-kinase (PI3K), and Janus kinase/signal transducer...
Combined Gout and Pseudogout Demonstrate Unique Clinicopathologic Features Compared to Those With Only Gout [0.03%]
与单纯痛风相比，合并痛风及假性痛风的临床病理特征独有独特之处
Sandra Gjorgova Gjeorgjievski,Josephine K Dermawan,John D Reith et al.
Sandra Gjorgova Gjeorgjievski et al.
Although monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals have been documented together in synovial fluid, there are no descriptions regarding their simultaneous histologic presence within the same tophi. Furthermore, th...
Utility of Protein Kinase C Beta II Immunohistochemistry in Differential Diagnosis of Ewing Sarcoma [0.03%]
蛋白质激酶CβII免疫组化在尤因肉瘤鉴别诊断中的应用价值研究
Jerzy Lasota,Martyna Krupińska,Maciej Kaczorowski et al.
Jerzy Lasota et al.
The diagnosis of Ewing sarcoma can be challenging, particularly when the tumor is present in an atypical location and resembles histologic mimics. The hallmark feature of Ewing sarcoma is chromosomal translocation, t(11;22)(q24;q12), involv...