Gastric-Type Adenomas of the Nonampullary Duodenum: Reappraisal of Clinicopathological and Molecular Features and a Proposal for Novel Classification [0.03%]
非壶腹部十二指肠胃型腺瘤的临床病理和分子特征再评价及新型分类建议
Hidetaka Yamamoto,Shinichiro Kawatoko,Yumi Oshiro et al.
Hidetaka Yamamoto et al.
Nonampullary duodenal neoplasms of gastric phenotype include pyloric gland adenoma, foveolar-type adenoma, and duodenal neoplasm of uncertain malignant potential. In addition, previously undesignated epithelial tumors have been observed in ...
Micronests in Tumor Stroma is a Prognostic Classifier in Nasopharyngeal Carcinoma [0.03%]
肿瘤基质中的微巢是鼻咽癌预后分类的标志物
Alhadi Almangush,Miia Ruuskanen,Jaana Hagström et al.
Alhadi Almangush et al.
The assessment of micronests in tumor stroma has been introduced recently for the prognostication of human malignancies. In this multicenter study, we included a total of 110 patients treated for nasopharyngeal carcinoma (NPC) at one of the...
NFATC2::NUTM2 Fusion Defines a Novel Primary Pulmonary Epithelial Tumor With a Distinctive Immunophenotype [0.03%]
NFATC2::NUTM2融合定义了一种具有独特免疫表型的新型原发性肺上皮肿瘤
Lanlan Feng,Qiao Liu,Xiaoyan Liu et al.
Lanlan Feng et al.
With the application of molecular techniques in pathologic diagnosis, several novel primary pulmonary epithelial tumors have been continuously discovered and classified under the WHO classification of thoracic tumors. Recently, a pulmonary ...
BEND2 Immunohistochemistry as a Useful Diagnostic Marker for Astroblastomas With BEND2 Fusion [0.03%]
BEND2免疫组化可作为具有BEND2融合的星形细胞瘤的有用诊断标记
Haruna Okuno,Takuma Nakashima,Yasuhito Arai et al.
Haruna Okuno et al.
Astroblastoma, MN1-altered, is a newly recognized entity in the 5th edition of the WHO Classification of CNS Tumors. Its genetic definition is the presence of an alteration, most commonly gene fusions, in the MN1 gene, with BEND2 being the ...
The Extended Spectrum of Morphologic and Molecular Findings in ALK Fusion Spitz Neoplasms: A Study of 144 Cases [0.03%]
144例ALK融合Spitz肿瘤形态及分子特征的研究
Lindsay J Holic,Nithya S Trichy,Jonathan Braat et al.
Lindsay J Holic et al.
A comprehensive understanding of newly described tumors is often an evolutionary process. In this study, we describe the extended spectrum of morphologic patterns in a cohort of 144 ALK fusion Spitz neoplasms and provide the largest data se...
Urinary Bladder Leiomyomas: A Clinicopathological Series With Hormone Receptor, HMGA2, 2SC, and Fumarate Hydratase Status Assessment [0.03%]
尿道膀胱平滑肌瘤的临床病理系列研究及其激素受体、HMGA2、2SC和富马酸水合酶状态评估
Raul E Perret,Melissa Hruby,Carina A Dehner et al.
Raul E Perret et al.
Leiomyomas (LMs) represent the most frequent mesenchymal tumors of the urinary bladder. Despite their relative frequency, large clinicopathological studies are scarce, and their pathogenesis remains poorly understood. In this study, we perf...
Occult Breast Carcinoma: Pathologic Features of an Uncommon Clinical Presentation in a Large Cohort [0.03%]
隐匿性乳腺癌的大规模病理特征分析
Atif A Hashmi,Timothy M D&#x;Alfonso,Edi Brogi et al.
Atif A Hashmi et al.
Occult breast carcinoma (OBC) refers to the clinical presentation of breast carcinoma occurring in axillary lymph node(s) without a detectable primary breast cancer. Prior studies of OBC have focused on treatment regimens. We sought to stud...
Clinicopathological and Molecular Features of Glycogen-Rich Breast Carcinoma [0.03%]
富糖原型乳腺癌的临床病理和分子特征
Burcu Karadal-Ferrena,James P Solomon,Neal Lindeman et al.
Burcu Karadal-Ferrena et al.
Since its description by Hull and colleagues in 1981, several case series have described the clinicopathological features of glycogen-rich breast carcinoma (GRC); however, no detailed genetic study has been performed. We identified 10 patie...
Adnexal Endometrioid Carcinomas With Sex Cord-Like Morphology are Frequently PAX8-Negative, SOX17-Positive, and Enriched for CTNNB1 Alterations [0.03%]
具有性索样形态的附件黏液腺癌患者常常PAX8阴性和SOX17阳性且CTNNB1发生改变
Krisztina Lengyel,Alexis Musick,Adam S Fisch et al.
Krisztina Lengyel et al.
Sex cord-like morphology is now a well-known feature of occasional examples of endometrioid carcinoma of the ovary or fallopian tube. Recently, we have observed that these tumors are frequently negative for PAX8, prompting us to review thei...
Michael Torbenson,Chantal E McCabe,Jessica D Hohenstein et al.
Michael Torbenson et al.
CTNNB1-mutated hepatocellular carcinomas are characterized by a distinctive morphology and activation of the Wnt pathway. AXIN1 also plays a key role in the Wnt pathway, but the morphology of AXIN1-mutated tumors has not been examined. In a...