Hidradenoma in Axillary Lymph Nodes: A Diagnostic Pitfall Mimicking Metastatic Carcinoma [0.03%]
腋窝淋巴结中的汗腺瘤：一种模拟转移性癌的诊断陷阱
Gregory R Bean,Leandra G Kingsley,Jennifer Tan et al.
Gregory R Bean et al.
Axillary lymph nodes are a common site of metastatic carcinoma, particularly from the breast. Epithelial inclusions within axillary lymph nodes are uncommon but well recognized, most frequently encountered as small, incidental clusters of m...
Expanding the Spectrum of Ubiquitin-specific Proteases-Fused Neoplasms: A Clinicopathologic and Molecular Study of USP2- and USP8-Rearranged Spindle Cell Tumors [0.03%]
泛素特异性蛋白酶融合肿瘤的临床病理和分子特征研究：USP2和USP8重排梭形细胞肿瘤的 clinicopathologic 和 molecular 研究
Diane Frankel,Anne-Claire Marsan-Fratini,François Le Loarer et al.
Diane Frankel et al.
Mesenchymal spindle cell tumors represent a heterogeneous group of neoplasms defined by distinct clinicopathologic features and diverse molecular alterations. While USP6 rearrangements are well-established in nodular fasciitis and related e...
Discontinuous Involvement of the Spermatic Cord by Germ Cell Tumors Should Not Be Considered Pathologic Stage M1: An International Multi-Institutional Study [0.03%]
生殖细胞肿瘤不连续累及精索不是病理M1期：一项国际多中心研究
João Lobo,Dheeraj Chinnam,Kvetoslava Michalova et al.
João Lobo et al.
In testicular germ cell tumors (TGCTs), staging is a major determinant of disease-specific outcomes and dictates clinical management. The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual recommends that tumor depo...
Low-Grade Nasopharyngeal Papillary Adenocarcinoma: Toward a Better Molecular, Epigenetic, and Clinicopathological Understanding With Ontological Perspective [0.03%]
低级别鼻咽乳头状腺癌：从本体论角度更好地理解其分子、表观遗传和临床病理特征
Eric Lagrue,Nazim Benzerdjeb,Marick Laé et al.
Eric Lagrue et al.
This study reports 6 cases of low-grade nasopharyngeal papillary adenocarcinoma (LGNPPA) reviewed by the REFCOR network, integrating clinicopathological, genetic, and epigenetic analyses to refine our understanding of its histogenesis and b...
Enteroblastic and Hepatoid Colorectal Carcinomas are Aggressive Cancers With a Distinctive Immunophenotype, While Clear Cell Carcinoma Appears to Represent Clear Cell Change in Conventional Colorectal Cancer [0.03%]
肠上皮样肝样型结直肠癌是一组免疫表型特征独特的侵袭性肿瘤，而透明细胞 carcinoma 是结直肠腺癌的特殊变异型
Fahad Khan,Alexandros D Polydorides,John D Paulsen et al.
Fahad Khan et al.
Enteroblastic, hepatoid, and clear cell carcinomas are rare subtypes of colorectal carcinoma (CRC) with histologic and immunohistochemical (IHC) overlap. We assessed 37 CRCs that possibly represent these subtypes. Provisional criteria for e...
The Clinicopathologic and Genomic Features of Mature Versus Blastic Plasmacytoid Dendritic Cell Neoplasms Arising From Chronic Myeloid Neoplasms [0.03%]
慢性髓系肿瘤中成熟型与促纤维增生型浆细胞样树突状细胞瘤的临床病理和基因组特征比较研究
Sarah J Wu,Christopher B Hergott,Gabriel K Griffin et al.
Sarah J Wu et al.
Clonal mature plasmacytoid dendritic cell proliferations (MPDCP) are a recently recognized entity in the WHO fifth edition, but their pathologic spectrum remains poorly characterized. Cases with extensive MPDCP in the bone marrow (BM) are r...
Wei Chen,Honghai Xu,Kara Wegermann et al.
Wei Chen et al.
Autoimmune hepatitis-primary biliary cholangitis (AIH-PBC) overlap syndrome remains a diagnostic challenge due to the absence of standardized criteria and the limitations of current frameworks, such as the Paris Criteria. In this retrospect...
Genome-Wide Copy-Number Landscape of Germ Cell Tumors With Synchronous Conventional and "Somatic-Type" Malignancy Components [0.03%]
生殖细胞肿瘤中同步发生生精型与非生精型恶性肿瘤的全基因组拷贝数景观分析
Kvetoslava Michalova,Melissa Hruby,Nicholas Baniak et al.
Kvetoslava Michalova et al.
So-called "somatic-type" malignancies (SMs) of germ cell tumor (GCT) origin resemble malignant neoplasms that arise from true somatic tissue. Except for enrichment in TP53 pathway alterations, the mutational profile of GCTs with SMs does no...
Clinicopathologic and Molecular Characteristics of Merkel Cell Polyomavirus Positive T-Cell Lymphoproliferative Disorders [0.03%]
Merkel细胞多瘤病毒阳性T细胞淋巴增生性疾病的临床病理和分子特征
Philip Bulterys,Christine W Zhou,Shunyou Gong et al.
Philip Bulterys et al.
Previous work described 3 cases of CD4+ T-cell lymphomas harboring Merkel cell polyomavirus (MCPyV), as demonstrated by in situ hybridization (ISH), next generation sequencing, and polymerase chain reaction. Two of these cases were cutaneou...
Columnar Cell Subtype of Papillary Thyroid Carcinoma Is Characterized By A High Frequency of High-Grade Tumors That Exhibit Aggressive Clinicopathologic Features and Poor Outcomes: A Multicenter Study of 71 Cases [0.03%]
柱状细胞型乳头状甲状腺癌以高级别肿瘤的高发为特征，且此类肿瘤临床病理表现具有侵袭性及预后不良：71例多中心研究
Kartik Viswanathan,Bayan Alzumaili,Ahmed Lazim et al.
Kartik Viswanathan et al.
Papillary thyroid carcinoma, columnar cell subtype (PTC-CC) is a PTC characterized by nuclear pseudostratification and elongation. High-grade differentiated thyroid carcinoma is a novel classification of the WHO classification, defined by m...