MUC4-Positive Fibroblastoma: Clinicopathological and Molecular Analysis of 7 Cases [0.03%]
MUC4阳性纤维肉瘤:7例临床病理及分子分析
Akihiko Yoshida,Naohiro Makise,Ken-Ichi Yoshida et al.
Akihiko Yoshida et al.
In soft tissue pathology, MUC4 is considered a sensitive and specific immunohistochemical marker for low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma (SEF), which are characterized by FUS/EWSR1::CREB3L2/1 fusion...
Marginal Zone Lymphoma With T-Follicular Helper Hyperplasia: Paving the Way for New Concepts in Cellular Plasticity and Unveiling Histopathologic Pitfalls [0.03%]
边缘区淋巴瘤伴T滤泡辅助细胞增生:探索细胞转化的新概念及揭示组织病理学陷阱
Marie Donzel,Alexis Trecourt,Juliette Fontaine et al.
Marie Donzel et al.
The expression of T-follicular helper (TFH) markers, initially described in nodal T-cell lymphomas arising from TFH-cells, has been reported in several non-TFH lymphomas, including B-cell lymphomas. It has also been observed in marginal zon...
Expanding HPV-Related Multiphenotypic Sinonasal Carcinoma Morphologic and Genotyping Profile: A Clinicopathological Study of 52 Latin American Cases [0.03%]
扩大人乳头瘤病毒相关多表型鼻腔和副鼻窦癌形态学和基因分型谱系:南美52例患者的临床病理研究
João P Gonçalves de Paiva,Ana L Carrinho Ayroza Rangel,João Epaminondas Silva de Araújo et al.
João P Gonçalves de Paiva et al.
This study characterized a cohort of 52 cases of HPV-related multiphenotypic sinonasal carcinoma (HMSC) from Latin America, integrating clinicopathological, immunohistochemical, HPV genotyping, and prognostic data. HMSC predominantly arose ...
Gynecologic Pathologist Agreement on Presence and Quantification of Lymphovascular Invasion in Low-stage, Low-grade Endometrial Endometrioid Adenocarcinoma [0.03%]
低级别早期子宫内膜内膜样腺癌淋巴管侵犯的诊断和分级中的妇科病理学家共识达成率研究
Darrell Martin,Sakinah Thiryayi,Katherine Grondin et al.
Darrell Martin et al.
Lymphovascular invasion (LVI) is a prognostic and treatment-driving parameter for low-stage, low-grade endometrial endometrioid adenocarcinoma (EEAC). There is lack of organizational recommendations/guideline consensus regarding the clinica...
The Value of Systematic Versus Targeted Sampling in Prostate Cancer Detection and the Identification of Adverse Pathologic Features: A Retrospective Review of Over 1400 Combined Prostate Biopsies [0.03%]
系统采样与靶标采样在前列腺癌检测及不利病理特征识别中的作用:对1400多例联合前列腺活检的回顾性分析
Ngoc-Nhu Jennifer Nguyen,Vincent F Castillo,Ekaterina Olkhov-Mitsel et al.
Ngoc-Nhu Jennifer Nguyen et al.
The value of systematic biopsy (SBx) versus targeted biopsy (TBx) in the detection of prostate cancer and its adverse pathologic (AP) features was compared using a multi-institutional cohort of combined prostate biopsies with treatment-naiv...
Papillary Squamous Intraepithelial Lesion Outside the Uterine Cervix: Clinicopathological Characterization and Immunohistochemical Study [0.03%]
子宫颈外乳头状鳞状上皮内病变的临床病理特征及免疫组化研究
Gloria Zhang,Xuefeng Zhang,Robert A Soslow et al.
Gloria Zhang et al.
Papillary immature metaplasia, originally described in the uterine cervix, is increasingly recognized as a distinctive squamous intraepithelial lesion rather than a true metaplastic process. Accordingly, the term papillary squamous intraepi...
International Society of Urological Pathology Consensus on Cancer Precursor Lesions: Working Group 3 Preneoplastic and Precursor Lesions of the Kidney [0.03%]
国际泌尿病理学会关于癌前病变的共识:肾脏癌前病变工作组第3组
Sean R Williamson,Sara E Wobker,Rohit Mehra et al.
Sean R Williamson et al.
Compared with cancers of other organs, precursor lesions of renal cell neoplasms are rarely discussed. However, there are specific scenarios where cysts or microscopic solid lesions are thought to precede tumor formation. In 2024, the Inter...
TTF-1 Is a Sensitive and Specific Immunohistochemical Marker for Autoimmune Gastritis [0.03%]
TTF-1 是自身免疫性胃炎敏感而特异的免疫组化标记物
Deepa Kumari,Fazilet Yilmaz,Dongfang Yang et al.
Deepa Kumari et al.
Autoimmune gastritis (AIG) is an inflammatory disorder that leads to corpus-restricted mucosal atrophy and is associated with the formation of well-differentiated neuroendocrine tumors and, possibly, gastric adenocarcinoma. The early histol...
Whole-Exome Sequencing Identifies Frequent AHNAK2 Mutations With Prognostic Significance in Undifferentiated Primary Liver Carcinoma [0.03%]
整个外显子组测序鉴定出非分化原发性肝癌中频繁出现的AHNAK2基因突变并具有预后价值
Ziqi Zhu,Qing Tao,Liangyin Chen et al.
Ziqi Zhu et al.
Undifferentiated primary liver carcinoma (UPLC) is an exceedingly rare hepatic malignancy lacking hepatocytic or cholangiocytic differentiation, and its clinicopathologic and molecular characteristics remain poorly defined. We retrospective...
Eosinophilic Pattern of Chromophobe Renal Cell Carcinoma is More Aggressive Than the Classic Pattern: A Comprehensive Morphologic and Genomic Analysis [0.03%]
嗜酸细胞型肾嫌色细胞癌的侵袭性较经典型更强:全面形态学和基因组分析结果证实
Abraam Zakhary,Vincent F P Castillo,Kiril Trpkov et al.
Abraam Zakhary et al.
Chromophobe renal cell carcinoma (chRCC) is generally considered an indolent malignancy; however, studies have produced conflicting results regarding the differences among its histologic patterns. The prognostic significance of eosinophilic...