Extensive Pathologic Invasion and Prognostic Implication of Gastric-Type Cervical Adenocarcinoma: A Comparative Analysis With Human Papillomavirus-Associated Adenocarcinoma [0.03%]
胃型宫颈腺癌的广泛病理浸润及预后意义：与人乳头瘤病毒相关腺癌的对比分析
Kyosuke Kamijo,Tsutomu Miyamoto,Shiori Oshima et al.
Kyosuke Kamijo et al.
Gastric-type adenocarcinoma (GAS) is the most common subtype of human papillomavirus (HPV)-independent cervical adenocarcinomas and is associated with a poor prognosis. We used a gross morphologic classification system and imaging analysis ...
Insights into the Clinical Prognosis of High-grade Appendiceal Mucinous Neoplasms [0.03%]
高级别阑尾黏液性肿瘤的临床预后判断
Peggy Dartigues,Vahan Kepenekian,Claire Illac-Vauquelin et al.
Peggy Dartigues et al.
High-grade appendiceal mucinous neoplasm (HAMN) is used to describe a rare epithelial neoplasm of the appendix characterized by pushing-type invasion and high-grade cytologic atypia. Its implications regarding lymph node spread and the nece...
Ivan J Stojanov,Anna M Trzcinska,Mohammed Qaisi et al.
Ivan J Stojanov et al.
Ameloblastoma is characterized histologically by evidence of ameloblastic differentiation and molecularly by MAPK pathway alterations, most frequently BRAFV600E mutation and RAS mutations, as well as by SMO mutations. This mutational profil...
BRAF Gene Fusions in Melanoma: First Kinase Domain Duplication, New Fusion Partners, and Clinical Outcomes [0.03%]
黑色素瘤中BRAF基因融合：首次发现激酶结构域重复、新的融合伴侣及临床结果
Igor Odintsov,Dale Davis,Daniel Pissaloux et al.
Igor Odintsov et al.
BRAF gene fusions have been well-described in Spitzoid melanocytic lesions but can also occur uncommonly in conventional melanomas. Here we report a series of 17 melanomas harboring BRAF gene fusions as their putative primary genetic driver...
Breast Carcinomas Resembling Acinic Cell Carcinoma: Comprehensive Analysis of 14 Cases and Review of the Literature [0.03%]
类似腺导管细胞癌的乳腺癌：14例综合分析及文献回顾
Fengxia Qin,Jiazhen Li,Yi Zheng et al.
Fengxia Qin et al.
Acinic cell carcinoma (AciCC) of the breast is an exceptionally rare subtype of invasive breast carcinoma, often exhibiting a triple-negative phenotype and relatively indolent behavior. Since the first case reported by Roncaroli and colleag...
Clinicopathologic and Molecular Characterization of Gynecologic Carcinosarcomas With a Mesonephric-Like Carcinomatous Component [0.03%]
具有中肾小管样癌成分的女性生殖道 carcinosarcoma 的临床病理及分子特征分析
Rachelle P Mendoza,Melisa Y Tjota,Donghyuk N Choi et al.
Rachelle P Mendoza et al.
Carcinosarcoma with a mesonephric-like carcinomatous component (MLCS) is a rare subtype of gynecologic malignancy recently described in the literature. This study aims to expand the genomic characterization of MLCS by performing independent...
Clinicopathologic Features and Viral Status of Low-risk HPV6 and HPV11-Associated Squamous Cell Carcinoma of the Uterine Cervix and Vulva [0.03%]
低风险HPV6和HPV11相关宫颈和外阴鳞状细胞癌的临床病理特征及病毒状态
Guy A Williams nd,Annie A Wu,Henrietta C Eugene et al.
Guy A Williams nd et al.
Despite being designated as "noncarcinogenic" human papillomavirus (HPV) types, mono-infection with HPV6 or HPV11 has been found in squamous cell carcinomas (SCCs) at specific sites, including the larynx, penis, anus, and rarely, the lower ...
SALL4 as a Useful Marker for the Distinction of Various Gestational Trophoblastic Disease Subtypes: Choriocarcinoma From Other Trophoblastic Lesions and Early Complete Hydatidiform Mole From Partial Mole and NonMolar Villi [0.03%]
SALL4作为一种有用的标志物用于区分各种妊娠滋养细胞疾病亚型：合体细胞癌和其他滋养细胞肿瘤及早期完全性葡萄胎与不完全性葡萄胎和非葡萄胎组织的区别标记物性质的研究
Alexis Trecourt,Marie Donzel,Lucie Gaillot-Durand et al.
Alexis Trecourt et al.
The distinction between choriocarcinoma and residual trophoblastic cell proliferation from a complete hydatidiform mole/invasive mole (CHM/IM) without villi is challenging on curettage materials. We investigated whether SALL4 immunostaining...
Prospective Fumarate Hydratase Tumor Predisposition Syndrome Screening in Patients With Uterine Smooth Muscle Tumors: Age, Morphology, Fumarate Hydratase/S-(2-succino) Cysteine Immunohistochemistry, and Germline Testing [0.03%]
子宫平滑肌肿瘤患者的丙酮酸脱氢酶肿瘤易感综合征筛查：年龄、形态、丙酮酸脱氢酶/(2- succino)半胱氨酸免疫组化和遗传咨询测试的回顾性分析
Austin McHenry,Ashley Monsrud,Jennifer Pors et al.
Austin McHenry et al.
Fumarate hydratase tumor predisposition syndrome (FHTPS) is caused by germline fumarate hydratase (FH) pathogenic variants (PVs). Most women with FHTPS develop FH-deficient (FHD) uterine leiomyomas (ULs), which arise 10 to 15 years earlier ...
A Novel Case of Pulmonary Sclerosing Diffuse PEComatosis With Neuroendocrine Cell Hyperplasia [0.03%]
多器官平滑肌瘤病并发肺弥漫性血管黏液瘤伴神经内分泌细胞增生症一例报告
Kristine E Konopka,Ella A Kazerooni,MeiLan K Han et al.
Kristine E Konopka et al.
Proliferations of neoplastic perivascular epithelioid cells (PECs) may occur within the lung and extrathoracic sites. The term "PEComatosis" is applied to multiple or diffuse microscopic proliferations of neoplastic PECs. Pulmonary diffuse ...