Brain Atrophy Is Substantially Accelerated in Neurological Wilson's Disease: A Longitudinal Study [0.03%]
威尔逊病患者脑萎缩纵向研究：神经型威尔逊病患者脑萎缩速度明显加快
Lukasz Smolinski,Tjalf Ziemssen,Katja Akgun et al.
Lukasz Smolinski et al.
Background: Although brain atrophy is common in neurological Wilson's disease, longitudinal studies are lacking. Objective: The objecti...
Prevalence and Incidence of Huntington's Disease: An Updated Systematic Review and Meta-Analysis [0.03%]
亨廷顿舞蹈病的患病率和发病率：一项系统综述和meta分析更新
Alex Medina,Yasamin Mahjoub,Larry Shaver et al.
Alex Medina et al.
The incidence and prevalence of Huntington's disease (HD) based on a systematic review and meta-analysis of 20 studies published from 1985 to 2010 was estimated at 0.38 per 100,000 person-years (95% confidence interval [CI], 0.16-0.94) and ...
Disease Progression, Resilience, and Inflammation Markers During the Coronavirus Disease 2019 Pandemic in Parkinson's Disease [0.03%]
帕金森病患者新型冠状病毒肺炎流行期间的疾病进展、韧性及炎症标志物变化
Claire Pauly,Enrico Glaab,Maxime Hansen et al.
Claire Pauly et al.
Familial Cerebellar Ataxia and Amyotrophic Lateral Sclerosis/Frontotemporal Dementia with DAB1 and C9ORF72 Repeat Expansions: An 18-Year Study [0.03%]
DAB1和C9ORF72重复序列扩增引起家族性小脑共济失调及肌萎缩侧索硬化/额颞叶痴呆：一项为期18年的研究
Angela Rosenbohm,Hendrik Pott,Mirja Thomsen et al.
Angela Rosenbohm et al.
Background: Coding and noncoding repeat expansions are an important cause of neurodegenerative diseases. Objective: This study determin...
Progression of Clinical and Eye Movement Markers in Preataxic Carriers of Machado-Joseph Disease [0.03%]
马查多-约瑟夫病无症状基因携带者中临床及眼动异常的进展规律研究
Camila Maria de Oliveira,Vanessa Bielefeldt Leotti,Amanda Henz Cappelli et al.
Camila Maria de Oliveira et al.
Background: Little is known about preclinical stages of Machado-Joseph disease, a polyglutamine disorder characterized by progressive adult-onset ataxia. ...
Corticospinal Suppression Underlying Intact Movement Preparation Fades in Parkinson's Disease [0.03%]
帕金森病中完整运动准备下的皮质脊髓抑制减弱
Emmanuelle Wilhelm,Caroline Quoilin,Gerard Derosiere et al.
Emmanuelle Wilhelm et al.
Background: In Parkinson's disease (PD), neurophysiological abnormalities within the primary motor cortex (M1) have been shown to contribute to bradykinesia, but exact modalities are still uncertain. We propose that such ...
Early-Onset and Severe Complex Hereditary Spastic Paraplegia Caused by De Novo Variants in SPAST [0.03%]
SPAST基因从头变异导致的早发严重复杂遗传性共济失调痉挛性截瘫综合征
Alisa Mo,Afshin Saffari,Melanie Kellner et al.
Alisa Mo et al.
Background: Familial hereditary spastic paraplegia (HSP)-SPAST (SPG4) typically presents with a pure HSP phenotype. Objective: The aim ...
The Dawn of Precision Medicine for Deep Brain Stimulation in Parkinson's Disease? [0.03%]
精准医学在帕金森病深部脑刺激治疗的应用黎明？
Kelly A Mills,Gregory M Pontone
Kelly A Mills
Gaps, Controversies, and Proposed Roadmap for Research in Poststroke Movement Disorders [0.03%]
卒中后运动障碍研究中的空白、争议及建议的研究路线图
Sanjay Pandey,Juho Joutsa,Raja Mehanna et al.
Sanjay Pandey et al.
Poststroke movement disorders (PSMDs) are a common cause of secondary movement disorders. Although prior studies have highlighted the clinical spectrum and phenomenology of PSMDs, there are many knowledge gaps worth addressing. Some of the ...