GNAO1 Haploinsufficiency: The Milder End of the GNAO1 Phenotypic Spectrum [0.03%]
GNAO1单倍体不足：GNAO1表型谱系的轻度一端
Serena Galosi,Maria Novelli,Martina Di Rocco et al.
Serena Galosi et al.
Fiber-Specific White Matter Alterations in Parkinson's Disease Patients with GBA Gene Mutations [0.03%]
GBA基因突变帕金森病患者的白质异常
Christina Andica,Koji Kamagata,Wataru Uchida et al.
Christina Andica et al.
Background: Patients with Parkinson's disease (PD) carrying GBA gene mutations (GBA-PD) have a more aggressive disease course than those with idiopathic PD (iPD). ...
Autosomal Dominant MPAN: Mosaicism Expands the Clinical Spectrum to Atypical Late-Onset Phenotypes [0.03%]
常染色体显性MPAN：嵌合现象扩大了该疾病临床谱系的范围以包含非典型型迟发症狀群
Chloé Angelini,Christelle Marie Durand,Patricia Fergelot et al.
Chloé Angelini et al.
Background: Mitochondrial membrane protein-associated neurodegeneration (MPAN) is caused by mutations in the C19orf12 gene. MPAN typically appears in the first two decades of life and presents with progressive dystonia-pa...
Bone Mineral Density and the Risk of Parkinson's Disease in Postmenopausal Women [0.03%]
骨密度与绝经后妇女帕金森病风险的关系
Kye-Yeung Park,Jin-Hyung Jung,Hwan-Sik Hwang et al.
Kye-Yeung Park et al.
Background: Whether bone mineral density (BMD) is related to the risk of Parkinson's disease (PD) is unclear. Objectives: The objective...
Plant-Based Dietary Patterns and Parkinson's Disease: A Prospective Analysis of the UK Biobank [0.03%]
基于植物的饮食模式与帕金森病的关系：英国生物银行的前瞻性分析
Anna Tresserra-Rimbau,Alysha S Thompson,Nicola Bondonno et al.
Anna Tresserra-Rimbau et al.
Background: Plant-based diets have been associated with a lower risk of several chronic diseases, but the relationship with PD is unknown. Objectives: ...
Erythrocytic α-Synuclein Species as Biomarkers for Isolated Rapid Eye Movement Sleep Behavior Disorder [0.03%]
α-突触核蛋白血细胞作为单纯快速眼动睡眠行为障碍生物标志物的研究
Yuanchu Zheng,Huihui Cai,Xuemei Wang et al.
Yuanchu Zheng et al.
27-Hydroxycholesterol Drives the Spread of α-Synuclein Pathology in Parkinson's Disease [0.03%]
27-羟基胆固醇驱动帕金森病中α-突触核蛋白病理的扩散
Lijun Dai,Jiannan Wang,Xingyu Zhang et al.
Lijun Dai et al.
Background: The accumulation and aggregation of α-synuclein (α-Syn) are characteristic of Parkinson's disease (PD). Epidemiological evidence indicates that hyperlipidemia is associated with an increased risk of PD. The ...
Mild Motor Signs in Healthy Aging Are Associated with Lower Synaptic Density in the Brain [0.03%]
轻度运动征象与脑内较低的突触密度有关
Margot G A Van Cauwenberge,Aline Delva,Thomas Vande Casteele et al.
Margot G A Van Cauwenberge et al.
Objective: To investigate whether mild motor signs (MMS) in old age correlate with synaptic density in the brain. Background: Normal ag...