Tanya Simuni,Caroline Gochanour,Anuprita R Nair et al.
Tanya Simuni et al.
Background: Neuronal α-synuclein disease (NSD) is defined by the presence of an in vivo biomarker of neuronal alpha-synuclein (n-asyn) pathology. The NSD integrated staging system (NSD-ISS) for research describes progres...
Paired Deep Brain Stimuli Elicit Short-Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus [0.03%]
成对的深部脑刺激在苍白球内侧部和亚thalamic核中产生短期增强现象
Sarah Brinkerhoff,Arie Nakhmani,Alex Varghese et al.
Sarah Brinkerhoff et al.
Background: Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural respons...
Are there Predictors for the Effects of Subthalamic Versus Thalamic Lesions for the Treatment of Parkinsonian Tremor? [0.03%]
苍白球或丘脑毁损治疗帕金森病震颤的预后因素
Steffen Paschen,Elena Natera-Villalba,Jose A Pineda-Pardo et al.
Steffen Paschen et al.
Does Dopamine Sensitivity Influence the Choice between Subthalamotomy and Thalamotomy for Parkinsonian Tremor? [0.03%]
多巴胺敏感性影响帕金森病震颤患者选择 subthalamotomy 或 thalamotomy 吗？
Mickael Aubignat
Mickael Aubignat
Emmanuel Roze,Caroline Dubacq,Quentin Welniarz
Emmanuel Roze
The evolution of the corticospinal tract (CST) is closely linked to the development of skilled voluntary movements in mammals. The main evolutionary divergence concerns the position of the CST within the spinal cord white matter and its pos...
Expanding the Allelic and Clinical Heterogeneity of Movement Disorders Linked to Defects of Mitochondrial Adenosine Triphosphate Synthase [0.03%]
线粒体三磷酸腺苷合酶缺陷相关运动障碍的等位基因和临床异质性研究取得进展
Philip Harrer,Magdalena Krygier,Martin Krenn et al.
Philip Harrer et al.
Background: Defects of mitochondrial ATP synthase (ATPase) represent an emerging, yet incompletely understood group of neurodevelopmental diseases with abnormal movements. ...
Genetic Risk Factors in Normal Pressure Hydrocephalus: What We Know and What Is Next [0.03%]
正常压力性脑积水的遗传危险因素：我们所知及其未来方向
Camila C Piccinin,Saar Anis,Jeryl Ritzi T Yu et al.
Camila C Piccinin et al.
Knowledge of the genetic factors in normal pressure hydrocephalus (NPH) is rapidly evolving, with significant advances in recent years. We conducted a systematic review examining genetic contributions to NPH risk. Ovid Embase, Ovid Medline,...
Long-Read Sequencing: The Third Generation of Diagnostic Testing for Dystonia [0.03%]
长读测序：诊断扭转痉挛的第三代检测技术
Thomas Wirth,Kishore R Kumar,Michael Zech
Thomas Wirth
Long-read sequencing methodologies provide powerful capacity to identify all types of genomic variations in a single test. Long-read platforms such as Oxford Nanopore and PacBio have the potential to revolutionize molecular diagnostics by r...
Serge Przedborski,Bastiaan R Bloem,Vladimir S Kostic
Serge Przedborski
Molecular-Informed Network Analysis Unveils Fatigue-Related Functional Connectivity in Parkinson's Disease [0.03%]
基于分子信息的网络分析揭示帕金森病相关疲劳的功能连接性
Ilaria Antonella Di Vico,Manuela Moretto,Agnese Tamanti et al.
Ilaria Antonella Di Vico et al.
Background: Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non-motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network-based mechanisms remain poorly...