SCA4 Unravelled After More than 25 Years Using Advanced Genomic Technologies [0.03%]
利用先进的基因组技术攻克SCA4谜题——历经25年终成功
Laura Ivete Rudaks,Dennis Yeow,Kishore Raj Kumar
Laura Ivete Rudaks
Genome Aggregation Database Version 4-New Challenges of Variant Analysis in Movement Disorders [0.03%]
基因聚合数据库第4版-运动障碍变异分析的新挑战
Elisabetta Indelicato,Luigi Michele Romito,Philip Harrer et al.
Elisabetta Indelicato et al.
FARS-ADL across Ataxias: Construct Validity, Sensitivity to Change, and Minimal Important Change [0.03%]
小脑性共济失调患者功能评估问卷（FARS-ADL）的构建效度、敏感性和最小临床意义变化阈值研究
Andreas Traschütz,Zofia Fleszar,Holger Hengel et al.
Andreas Traschütz et al.
Background: Patient-focused outcomes present a central need for trial-readiness across all ataxias. The Activities of Daily Living part of the Friedreich Ataxia Rating Scale (FARS-ADL) captures functional impairment and l...
Novel PANK2 Variant in Asian Indians with Atypical Pantothenate Kinase Associated Neurodegeneration [0.03%]
印度亚洲人中罕见泛酸激酶相关神经退行性病变的新型PANK2变异体
Arti Saini,Vikram V Holla,Divya Kalikavil Puthanveedu et al.
Arti Saini et al.
Louise Buur,Jonas Wiedemann,Frank Larsen et al.
Louise Buur et al.
Background: Immunotherapy targeting pathological α-synuclein (α-syn) species is a promising strategy for slowing disease progression in neurodegenerative synucleinopathies, including Parkinson's disease (PD). ...
Short-Term Cannabidiol with Δ-9-Tetrahydrocannabinol in Parkinson's Disease: A Randomized Trial [0.03%]
帕金森氏症的短期CBD结合Δ-9-四氢大麻酚治疗：一项随机试验
Ying Liu,Jacquelyn Bainbridge,Stefan Sillau et al.
Ying Liu et al.
Background: Cannabis use is frequent in Parkinson's disease (PD), despite inadequate evidence of benefits and risks. Objective: The aim...
Randomized Controlled Trial
Movement disorders : official journal of the Movement Disorder Society. 2024 May;39(5):863-875. DOI:10.1002/mds.29768 2024
Joseph H Friedman
Joseph H Friedman
On-Demand Cueing for Freezing of Gait in Parkinson's Disease: A Randomized Controlled Trial [0.03%]
帕金森病冻结步态的按需提示：一项随机对照试验
Demi Zoetewei,Talia Herman,Pieter Ginis et al.
Demi Zoetewei et al.
Background: Cueing can alleviate freezing of gait (FOG) in people with Parkinson's disease (PD), but using the same cues continuously in daily life may compromise effectiveness. Therefore, we developed the DeFOG-system to...
Randomized Controlled Trial
Movement disorders : official journal of the Movement Disorder Society. 2024 May;39(5):876-886. DOI:10.1002/mds.29762 2024
Contribution of MRI for the Early Diagnosis of Parkinsonism in Patients with Diagnostic Uncertainty [0.03%]
MRI对诊断不确定的患者早期诊断帕金森病的贡献
Lydia Chougar,Alice Faucher,Johann Faouzi et al.
Lydia Chougar et al.
Background: International clinical criteria are the reference for the diagnosis of degenerative parkinsonism in clinical research, but they may lack sensitivity and specificity in the early stages. ...
Cognitive Impairment Is Part of the Phenotype of Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS) [0.03%]
认知障碍是小脑共济失调、神经病、前庭无反射综合征(CANVAS)表型的一部分
Kathy Dujardin,Céline Tard,Emily Diglé et al.
Kathy Dujardin et al.
Background: Little is known about the impact of the cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) on cognition. Objective: ...