Marianna Sarchioto,Jessica Frey,Christos Ganos et al.
Marianna Sarchioto et al.
Stepwise Functional Brain Architecture Correlates with Atrophy in Progressive Supranuclear Palsy [0.03%]
步进式功能脑结构与进行性核上性麻痹萎缩的相关性研究
Edoardo Gioele Spinelli,Alma Ghirelli,Ilaria Bottale et al.
Edoardo Gioele Spinelli et al.
Background: Stepwise functional connectivity (SFC) detects whole-brain functional couplings of a selected region of interest at increasing link-step topological distances. ...
Gamified Closed-Loop Intervention Enhances Tic Suppression in Children: A Randomized Trial [0.03%]
游戏化闭环干预可增强儿童抽动抑制：一项随机试验
Michael S Rotstein,Sharon Zimmerman-Brenner,Shiri Davidovitch et al.
Michael S Rotstein et al.
Background: Gamification of behavioral intervention for tic disorders (TDs) potentially enhances compliance and offers key clinical advantages. By delivering immediate positive feedback upon tic-suppression, games may cou...
Clinical and Molecular Profiling in GNAO1 Permits Phenotype-Genotype Correlation [0.03%]
临床和分子图谱分析使GNAO1的表型与基因型相关成为可能
Amaia Lasa-Aranzasti,Yonika A Larasati,Juliana da Silva Cardoso et al.
Amaia Lasa-Aranzasti et al.
Background: Defects in GNAO1, the gene encoding the major neuronal G-protein Gαo, are related to neurodevelopmental disorders, epilepsy, and movement disorders. Nevertheless, there is a poor understanding of how molecula...
Responsive Versus Continuous Deep Brain Stimulation for Speech in Essential Tremor: A Pilot Study [0.03%]
响应式与连续式深部脑刺激对特发性震颤患者的说话影响：一项试点研究
Stephanie Cernera,Sarah Long,Madison Kelberman et al.
Stephanie Cernera et al.
Background: Responsive deep brain stimulation (rDBS) uses physiological signals to deliver stimulation when needed. rDBS is hypothesized to reduce stimulation-induced speech effects associated with continuous DBS (cDBS) i...
Targeting Glucagon-Like Peptide 1 Signaling: A Potential Disease Modifying Therapy for Parkinson's Disease [0.03%]
靶向胰高血糖素样肽-1信号通路：可能用于修饰帕金森病病程的疗法
Yasuyoshi Kimura,Hideki Mochizuki
Yasuyoshi Kimura
An Online Mindfulness-Based Group Intervention for Tics: A Pilot Randomized Controlled Trial [0.03%]
面向抽动障碍患者的线上正念团体干预试点随机对照研究
Hannah E Reese,William Alan Brown,Berta Summers et al.
Hannah E Reese et al.
Background: Current treatments for Tourette syndrome (TS) and persistent tic disorder (PTD) are often insufficiently effective, inaccessible, and frequently associated with adverse events. Thus, we must continue to develo...
Pingping Song,Dimitri Krainc
Pingping Song
Parkinson's disease (PD) is characterized by preferential degeneration of midbrain dopaminergic neurons that contributes to its typical clinical manifestation. Mutations in the parkin gene (PARK2) represent a relatively common genetic cause...
Oxycodone or Higher Dose of Levodopa for the Treatment of Parkinsonian Central Pain: OXYDOPA Trial [0.03%]
羟考酮与高剂量左旋多巴治疗帕金森病性中枢痛的疗效比较：OXYDOPA研究
Christine Brefel-Courbon,Estelle Harroch,Ana Marques et al.
Christine Brefel-Courbon et al.
Background: Among the different types of pain related to Parkinson's disease (PD), parkinsonian central pain (PCP) is the most disabling. Objectives: ...
Ayush Agarwal,Pooja Sharma,Divyani Garg et al.
Ayush Agarwal et al.