Gait Analysis and Magnetic Resonance Imaging Characteristics in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder [0.03%]
快速眼动睡眠行为障碍患者的步态分析和磁共振影像特征
Elisabetta Sarasso,Andrea Gardoni,Sara Marelli et al.
Elisabetta Sarasso et al.
Background: Isolated rapid eye movement sleep behavioral disorder (iRBD) can precede neurodegenerative diseases. There is an urgent need for biomarkers to aid early intervention and neuroprotection. ...
Navigating Visual Challenges: How Parkinson's Disease Alters Cognitive Priorities in Visual Search [0.03%]
视觉挑战下的认知优先级改变：帕金森病对视觉搜索的影响
Sinem Balta Beylergil,Peggy Skelly,Ibrahim Quagraine et al.
Sinem Balta Beylergil et al.
Objective: Parkinson's disease (PD) hampers visual search tasks such as reading, driving, and navigation. We examined expectations from past experiences, guiding cognition and contextual priors, on visual search in PD. ...
Reduced Age-Dependent Penetrance of a Large FGF14 GAA Repeat Expansion in a 74-Year-Old Woman from a German Family with SCA27B [0.03%]
一名来自德国SCA27B家系的74岁女性FGF14 GAA重复扩增的年龄依赖性渗透率降低
David Pellerin,Jens Seemann,Andreas Traschütz et al.
David Pellerin et al.
Research Priorities on the Role of α-Synuclein in Parkinson's Disease Pathogenesis [0.03%]
帕金森病发病机制中α-突触核蛋白作用的研究优先级
Jacqueline Burré,Robert H Edwards,Glenda Halliday et al.
Jacqueline Burré et al.
Various forms of Parkinson's disease, including its common sporadic form, are characterized by prominent α-synuclein (αSyn) aggregation in affected brain regions. However, the role of αSyn in the pathogenesis and evolution of the disease...
Long-Read Sequencing Unravels the Complexity of Structural Variants in PRKN in Two Individuals with Early-Onset Parkinson's Disease [0.03%]
长读序列表征两例早发性帕金森病患者中PRKN基因结构变异的复杂性
Guillaume Cogan,Kensuke Daida,Kimberley J Billingsley et al.
Guillaume Cogan et al.
Investigating the Protective Role of the Mitochondrial 2158 T > C Variant in Parkinson's Disease [0.03%]
探究线粒体2158T>C变异在帕金森病中的保护作用
Fulya Akçimen,Vesna van Midden,S Can Akerman et al.
Fulya Akçimen et al.
Understanding REM Sleep Behavior Disorder through Functional MRI: A Systematic Review [0.03%]
通过功能磁共振成像理解快动眼睡眠行为障碍的系统评价研究
Lachlan Churchill,Yu-Chi Chen,Simon J G Lewis et al.
Lachlan Churchill et al.
Neuroimaging studies in rapid eye movement sleep behavior disorder (RBD) can inform fundamental questions about the pathogenesis of Parkinson's disease (PD). Across modalities, functional magnetic resonance imaging (fMRI) may be better suit...
Advantages and Challenges of Platform Trials for Disease Modifying Therapies in Parkinson's Disease [0.03%]
帕金森病疾病修正治疗平台试验的优势与挑战
Margherita Fabbri,Olivier Rascol,Tom Foltynie et al.
Margherita Fabbri et al.
Traditional drug development in Parkinson's disease (PD) faces significant challenges because of its protracted timeline and high costs. In response, innovative master protocols are emerging and designed to address multiple research questio...
Abhishek Lenka,Vishal M Perera,Alberto J Espay et al.
Abhishek Lenka et al.
The term "catatonia" was introduced by German psychiatrist Karl Kahlbaum in 1874. Although historically tied to schizophrenia, catatonia exhibits a diverse range of phenotypes and has been observed in various medical and neuropsychiatric co...
Reply to: "Advancing Understanding of Predictive Factors for Survival in Friedreich's Ataxia: A Review of Current Evidence and Future Directions" [0.03%]
弗里德赖希共济病生存预测因素研究的当前证据及未来方向综述答复论文
Elisabetta Indelicato,Sylvia Boesch
Elisabetta Indelicato