Stress in Musicians with and Without Focal Dystonia Is Not Reflected in Limbic Circuit Activation [0.03%]
伴有和不伴有局灶性肌张力障碍的音乐家的压力并未在边缘回路激活中反映出来
Stine Alpheis,Christopher Sinke,Julian Burek et al.
Stine Alpheis et al.
Background: Musicians' dystonia (MD) is a movement disorder with several established risk factors, but the exact pathophysiology remains unknown. Recent research suggests dysfunction in sensory-motor, basal ganglia, cereb...
Team Science Approaches to Unravel Monogenic Parkinson's Disease on a Global Scale [0.03%]
全球范围解开单基因帕金森病的团队科学研究方法
Johanna Junker,Lara M Lange,Eva-Juliane Vollstedt et al.
Johanna Junker et al.
Background: Until recently, about three-quarters of all monogenic Parkinson's disease (PD) studies were performed in European/White ancestry, thereby severely limiting our insights into genotype-phenotype relationships at...
Ida Jensen,Stephanie Stiel,Sarah Bebermeier et al.
Ida Jensen et al.
Objective: The Progressive Supranuclear Palsy quality of life scale (PSP-QoL) has been shown to be a useful tool for capturing health-related quality of life of patients in "everyday life" and in progressive supranuclear ...
Sensitivity of Advanced Magnetic Resonance Imaging to Progression over Six Months in Early Spinocerebellar Ataxia [0.03%]
高级磁共振 imaging 在早期脊髓小脑共济失调6个月内的进展敏感性
Thiago J R Rezende,Emilien Petit,Young Woo Park et al.
Thiago J R Rezende et al.
Background: Clinical trials for upcoming disease-modifying therapies of spinocerebellar ataxias (SCA), a group of rare movement disorders, lack endpoints sensitive to early disease progression, when therapeutics will be m...
Prokineticin-2 Is Highly Expressed in Colonic Mucosa of Early Parkinson's Disease Patients [0.03%]
普罗kinsin-2在早期间质炎患者结肠黏膜中的高表达
Gabriele Bellini,Francesco Rettura,Giovanni Palermo et al.
Gabriele Bellini et al.
Background: Elevated levels of prokineticin-2 (PK2), regarded as a protein involved in modulating immune/inflammatory responses, have been detected in the substantia nigra, serum, and olfactory neurons of Parkinson's dise...
Linking Invasive and Noninvasive Brain Stimulation in Parkinson's Disease: A Randomized Trial [0.03%]
帕金森病的侵入性和非侵入性脑刺激关联的随机试验
Lukas L Goede,Simon Oxenford,Daniel Kroneberg et al.
Lukas L Goede et al.
Background: Recent imaging studies identified a brain network associated with clinical improvement following deep brain stimulation (DBS) in Parkinson's disease (PD), the PD response network. ...
Randomized Controlled Trial
Movement disorders : official journal of the Movement Disorder Society. 2024 Nov;39(11):1971-1981. DOI:10.1002/mds.29940 2024
Parkinson's Disease Gene Screening in Familial Cases from Central and South America [0.03%]
中美和南美地区帕金森病家族病例的基因筛查
Oswaldo Lorenzo-Betancor,Seysha Mehta,Janvi Ramchandra et al.
Oswaldo Lorenzo-Betancor et al.
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease following Alzheimer's disease. Nearly 30 causative genes have been identified for PD and related disorders. However, most of these g...
Annika Kluge,Eva Schaeffer,Daniela Berg
Annika Kluge
Epidemiology of Huntington's Disease in Latin America: A Systematic Review and Meta-Analysis [0.03%]
拉丁美洲亨廷顿舞蹈病的流行病学：系统回顾和.meta.分析
Alex Medina Escobar,Tamara Pringsheim,Sylvia Gautreau et al.
Alex Medina Escobar et al.
Background: Latin America has played a crucial role in advancing our understanding of Huntington's disease (HD). However, previous global reviews include limited data from Latin America. It is possible that English-based ...
From Wilson's Disease to Neurodevelopmental Disorder with Involuntary Movements, Different Genetic Interpretations in a Female Patient [0.03%]
从威尔森病到神经发育障碍伴不自主运动——一名女性患者的两种不同遗传学诠释
Shan Jin,Zhengzhe Sun,Xiang Fang et al.
Shan Jin et al.
Background: A 19-year-old female patient presented at 2 years of age with dysarthria, incoherent speech, and unsteady ambulation. She is prone to leaning backward when walking and has involuntary movements of the whole bo...