Effect of GBA1 Mutations and APOE Polymorphisms on Survival and Progression Among Ashkenazi Jews with Dementia with Lewy Bodies [0.03%]
GBA1突变和APOE多态性对具有路易体痴呆的阿什肯纳兹犹太人存活率及病情进展的影响
Tamara Shiner,Gitit Kavé,Anat Mirelman et al.
Tamara Shiner et al.
Background: Glucocerebrosidase 1 (GBA1) mutations are associated with reduced survival in Parkinson's disease but their effect on survival in dementia with Lewy bodies (DLB) is unclear. ...
Quantitative Comparisons of Progressive Supranuclear Palsy Rating Scale Versions Using Item Response Theory [0.03%]
利用项目反应理论对进行性核上性麻痹量表版本进行定量比较
Mohamed Gewily,Elodie L Plan,Elham Yousefi et al.
Mohamed Gewily et al.
Background: Progressive supranuclear palsy (PSP) is a neurodegenerative, late-onset disease that is challenging in terms of assessment. The Progressive Supranuclear Palsy Rating Scale (PSPRS), a 28-item clinician-reported...
Potassium Channel Subunit Kir4.1 Mutated in Paroxysmal Kinesigenic Dyskinesia: Screening of an Italian Cohort [0.03%]
意大利人群中的钾通道kir4.1基因变异与阵发性运动诱发 dystonia关系的研究
Giovanna Zorzi,Federica Zibordi,Ugo Sorrentino et al.
Giovanna Zorzi et al.
Metagenomic Analysis Reveals Large-Scale Disruptions of the Gut Microbiome in Parkinson's Disease [0.03%]
元基因组分析揭示帕金森病患者肠道菌群的大范围紊乱现象
Avril Metcalfe-Roach,Mihai S Cirstea,Adam C Yu et al.
Avril Metcalfe-Roach et al.
Background: Parkinson's disease (PD) has been consistently linked to alterations within the gut microbiome. Objective: Our goal was to ...
Skin Tau Quantification as a Novel Biomarker in Huntington's Disease [0.03%]
亨廷顿病的新型生物标志物——皮肤tau定量分析法
Iñigo Ruiz-Barrio,Anna Vázquez-Oliver,Arnau Puig-Davi et al.
Iñigo Ruiz-Barrio et al.
Background: Emerging research implicates tau protein dysregulation in the pathophysiology of Huntington's disease. Objective: This stud...
Glucagon-Like Peptide-1 Receptor Agonists and Risk of Parkinson's Disease in Patients with Type 2 Diabetes: A Population-Based Cohort Study [0.03%]
基于人群的队列研究中的人群中GLP-1受体激动剂与2型糖尿病患者的帕金森病风险关系
Huilin Tang,Ying Lu,Michael S Okun et al.
Huilin Tang et al.
Background: Previous studies have suggested that glucagon-like peptide-1 receptor agonists (GLP-1RAs) may have a disease-modifying effect in the development of Parkinson's disease (PD), but population studies yielded inco...
Canine RNF170 Single Base Deletion in a Naturally Occurring Model for Human Neuroaxonal Dystrophy [0.03%]
犬RNF170单碱基缺失自然突变模型的构建及鉴定
Shawna R Cook,Cleo Schwarz,Julien Guevar et al.
Shawna R Cook et al.
Background: Neuroaxonal dystrophy (NAD) is a group of inherited neurodegenerative disorders characterized primarily by the presence of spheroids (swollen axons) throughout the central nervous system. In humans, NAD is het...
Automated Sleep Detection in Movement Disorders Using Deep Brain Stimulation and Machine Learning [0.03%]
基于深度脑刺激和机器学习的运动障碍自动睡眠检测技术
Arjun Balachandar,Yosra Hashim,Okeanis Vaou et al.
Arjun Balachandar et al.
Background: Automated sleep detection in movement disorders may allow monitoring sleep, potentially guiding adaptive deep brain stimulation (DBS). Objecti...
Detrimental but Not Doomed-Glial Activation in Rapid Eye Movement Sleep Behavior Disorder [0.03%]
有害但不致命：REM睡眠行为障碍中的胶质细胞活化
Shu-Ying Liu,Vesna Sossi
Shu-Ying Liu