Chronic Musculoskeletal Pain and Risk of Incident Parkinson's Disease: A 13-Year Longitudinal Study [0.03%]
慢性肌肉骨骼疼痛与帕金森病发病风险的纵向研究
Fatemeh Vazirian,Jing Tian,Jane Alty et al.
Fatemeh Vazirian et al.
Background: Chronic musculoskeletal pain often co-occurs with Parkinson's disease (PD); however, whether individuals with chronic pain have a higher risk of developing PD is unclear. ...
Cerebellar Transcranial Direct Current Stimulation in the Cerebellar Cognitive Affective Syndrome: A Randomized, Double-Blind, Sham-Controlled Trial [0.03%]
经颅直流电刺激治疗小脑认知情感综合征：随机双盲对照试验
Stacha F I Reumers,Roderick P P W M Maas,Dennis J L G Schutter et al.
Stacha F I Reumers et al.
Background: The cerebellar cognitive affective syndrome (CCAS) encompasses cognitive and affective symptoms in patients with cerebellar disorders, for which no proven treatment is available. ...
Focused Ultrasound Pallidothalamic Tractotomy in Cervical Dystonia: A Pilot Study [0.03%]
聚焦超声纹状体-丘脑束切开术治疗颈肌张力障碍的可行性研究
Shiro Horisawa,Ryo Saito,Bohui Qian et al.
Shiro Horisawa et al.
Background: No clinical trials have been reported on the use of focused ultrasound (FUS) for treating cervical dystonia. Objective: We ...
Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients of Bullous Pemphigoid with or without Parkinson's Disease [0.03%]
天疱疮伴或不伴帕金森病患者的皮肤活检磷酸化α-突触核蛋白检测
Shan Cao,Xiang Fang,Jianwen Wang et al.
Shan Cao et al.
Background: High positivity rate of skin phosphorylated α-synuclein (P-SYN) was observed in Parkinson's disease (PD). Bullous pemphigoid (BP) is one of the most common autoimmune skin diseases associated with PD. ...
Advancing Parkinson's Disease Research in Africa: A Strategic Training Framework of the Global Parkinson's Genetics Program [0.03%]
推动非洲帕金森病研究的战略培训框架——全球帕金森基因组计划的一部分
Kathryn Step,Esraa Eltaraifee,Inas Elsayed et al.
Kathryn Step et al.
Strong Correlation between Clinical Improvement and Low-Frequency Oscillations in Pediatric Dystonia [0.03%]
儿童扭转痉挛临床改善与低频震荡密切相关
Deborah Hubers,Larissa R Heideman,Mariëlle J Stam et al.
Deborah Hubers et al.
Combined Assessment of Function and Survival to Demonstrate the Effect of Treatment on Progressive Supranuclear Palsy [0.03%]
综合评估功能和生存期以展示治疗进行性核上性麻痹的效果
Massimiliano Germani,Irene Rebollo Mesa,Tim J Buchanan et al.
Massimiliano Germani et al.
Background: Progressive supranuclear palsy (PSP) is a rare and fatal neurodegenerative disorder for which there are currently no disease-modifying treatments. Recent trials of potential therapies had durations of 12 month...
A Homoplasmic MT-TV Mutation Associated with Mitochondrial Inheritance of Hereditary Spastic Paraplegia [0.03%]
与遗传性痉挛性截瘫母系遗传相关的同源多态性MT-TV基因突变
Yan Shi,Junhao Xie,Junyi Jiang et al.
Yan Shi et al.
Background: Hereditary spastic paraplegia (HSP) is characterized by progressive lower limb weakness and spasticity, with unknown genetic cause in many cases. ...
Emerging Molecular-Genetic Families in Dystonia: Endosome-Autophagosome-Lysosome and Integrated Stress Response Pathways [0.03%]
torsion dystonia分子遗传新家系：内吞体-自噬溶酶体和综合应急反应通路
Nicole Calakos,Michael Zech
Nicole Calakos
Advances in genetic technologies and disease modeling have greatly accelerated the pace of introducing and validating molecular-genetic contributors to disease. In dystonia, there is a growing convergence across multiple distinct forms of t...
Genetic and Epidemiological Insights into RAB32-Linked Parkinson's Disease [0.03%]
RAB32相关帕金森病的遗传和流行病学见解
Mandy Radefeldt,Sabrina Lemke,Kridsadakorn Chaichoompu et al.
Mandy Radefeldt et al.
Background: The p.Ser71Arg RAB32 variant was recently associated with Parkinson's disease (PD). Objective: The aim was to investigate t...