Omaveloxolone for the Treatment of Friedreich Ataxia: Efficacy, Safety, and Future Perspectives [0.03%]
奥马维洛克用于治疗弗里德希共济失调：疗效、安全性及未来展望
Saba Naghipour,Louise A Corben,Amy J Hulme et al.
Saba Naghipour et al.
18F-Florzolotau PET Imaging Unveils Tau Pathology in Dementia with Lewy Bodies [0.03%]
18F-氟佐罗塔乌PET影像技术揭示Lewy体痴呆中的tau病理学
Gan Tang,Jia-Ying Lu,Xin-Yi Li et al.
Gan Tang et al.
Background: Dementia with Lewy bodies (DLB) commonly exhibits a complex neuropathology, sharing characteristics with Alzheimer's disease (AD), including tau aggregates. However, studies using the 18F-AV-1451 tau tracer ha...
Jean-Michel Gracies,Katharine E Alter,Bo Biering-Sørensen et al.
Jean-Michel Gracies et al.
Response to Mortimer et al. "Clinical and molecular profiling in GNAO1 permits phenotype-genotype correlation" [0.03%]
Mortimer等“GNAO1的临床和分子特征表型基因分型相关性研究”的点评文章
Amaia Lasa-Aranzasti,Gonzalo P Solis,Vladimir L Katanaev et al.
Amaia Lasa-Aranzasti et al.
Reply to: "Clinical and Molecular Profiling in GNAO1 Permits Phenotype-Genotype Correlation" [0.03%]
“GNAO1的临床和分子图谱允许表型-基因型相关性”一文的回信
Mortimer Svec,Tobias Mantel,Michael Zech et al.
Mortimer Svec et al.
Early Changes in the Locus Coeruleus in Mild Cognitive Impairment with Lewy Bodies [0.03%]
轻度路易体认知障碍患者黑质蓝斑核早期改变特征及临床意义
Žaneta Železníková,L&#x;ubomíra Nováková,Lubomír Vojtíšek et al.
Žaneta Železníková et al.
Background: Although neuromelanin-sensitive magnetic resonance imaging (NM-MRI) has been used to evaluate early neurodegeneration in Parkinson's disease, studies concentrating on the locus coeruleus (LC) in pre-dementia s...
Gut Microbial Metabolites and Future Risk of Parkinson's Disease: A Metabolome-Wide Association Study [0.03%]
肠道微生物代谢产物与帕金森病的发病风险：一项代谢组范围的研究
Yujia Zhao,Yunjia Lai,Sirwan K L Darweesh et al.
Yujia Zhao et al.
Background: Alterations in gut microbiota are observed in Parkinson's disease (PD). Previous studies on microbiota-derived metabolites in PD were small-scale and post-diagnosis, raising concerns about reverse causality. ...
Potential Disease-Modifying Effects of Ganglioside GM1 Pulse Treatment on Spinocerebellar Ataxia Type 3, a Parallel-Group, Double-Blind, Randomized, Controlled Trial [0.03%]
GM1神经节苷脂间歇治疗小脑萎缩型脊髓小脑性共济失调的可能修正疾病进程作用：一项与假手术对照、双盲随机平行分组试验
Yong-Kang Chen,Hai-Yan Tian,Qing-Yong Zhu et al.
Yong-Kang Chen et al.
Background: Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant inherited neurodegenerative disorder for which there is currently no cure, nor effective treatment strategy. ...
Identification of Novel Genetic Loci Affecting Age at Onset of Parkinson's Disease: A Genome-wide Association Study [0.03%]
帕金森病发病年龄的全基因组关联研究识别出新型遗传位点
Yun Su Hwang,Sungyang Jo,Seung Hyun Lee et al.
Yun Su Hwang et al.
Background: The age at onset (AAO) of Parkinson's disease (PD) varies widely among individuals and significantly influences disease progression and prognosis. However, few genome-wide association studies (GWASs) have inve...
Alise Zagare,Ahmed Hemedan,Catarina Almeida et al.
Alise Zagare et al.
Background: Parkinson's disease (PD) is the second most common, and the fastest-growing neurodegenerative disorder with unclear etiology in most cases. Therefore, the identification of non-genetic risk factors for PD path...