Is Hypomethylation of the α-Synuclein Gene in Parkinson's Disease Patients Related to Chronic Levodopa Intake? [0.03%]
帕金森病患者的α-突触核蛋白基因低甲基化与慢性左旋多巴摄入有关吗？
Thomas Müller,Wilfried Kuhn
Thomas Müller
Brain Networks Route Neurodegeneration Patterns in Patients with Progressive Supranuclear Palsy [0.03%]
进行性核上性麻痹患者的脑网络决定神经退行性病变模式
Carla Palleis,Andrea Quattrone,Amir Dehsarvi et al.
Carla Palleis et al.
Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disease driven by 4-repeat τ pathology, which is thought to propagate across interconnected neurons. ...
Single-Interval and Rhythmic Temporal Prediction in Cervical Dystonia [0.03%]
单时隙和节奏时间预测在颈椎 dystonia 中的应用
Sara Terranova,Alessandro Botta,Martina Putzolu et al.
Sara Terranova et al.
Background: Cerebellar dysfunction disrupts memory-based temporal predictions (TPs), whereas basal ganglia dysfunction affects rhythm-based TPs. Investigating TPs in cervical dystonia (CD) may help to delineate the contri...
Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients [0.03%]
智利运动障碍患者的ZFHX3基因GGC重复序列扩张的鉴定
Paula Saffie-Awad,Abraham Moller,Kensuke Daida et al.
Paula Saffie-Awad et al.
Background: Hereditary ataxias are genetically diverse, yet up to 75% remain undiagnosed due to technological and financial barriers. The GGC repeat expansion in ZFHX3, responsible for spinocerebellar ataxia type 4 (SCA4)...
Roberto Erro,Cristiano Sorrentino,Paolo Barone
Roberto Erro
Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease [0.03%]
基因分析X染色体与帕金森病进展相关的遗传位点
Yu Liao,Hao Wu,Junhao Wang et al.
Yu Liao et al.
Background: Genetic variants on the X chromosome have been linked to susceptibility for Parkinson's disease (PD), but their roles in disease progression remain unclear. ...
Decade-Long Prodrome on Neuroimaging: Unique Insight into Probable Corticobasal Degeneration [0.03%]
长达十年的神经影像前驱期：可能皮质基底节变性的独特见解
Xin You Tai,Pieter M Pretorius,George K Tofaris
Xin You Tai
Using Digital Speech Markers to Classify Functional Speech Disorder: A Proof-of-Concept Pilot Study [0.03%]
基于数字语音标志的功能性语音障碍分类概念验证试点研究
Jennifer L Freeburn,Sara A Finkelstein,Christiana Westlin et al.
Jennifer L Freeburn et al.
Background: Functional speech disorder (FND-speech) is a subtype of functional neurological disorder, yet quantitative characterization of its motor and cognitive-linguistic features remains underexplored. ...
Microstructural Changes in the Tuberal Hypothalamus Correlate with Daytime Sleepiness in Lewy Body Disorders [0.03%]
路易体障碍患者下丘脑结构异常与日间思睡的相关性研究
Jesse S Cohen,Hamsanandini Radhakrishnan,Christopher A Olm et al.
Jesse S Cohen et al.
Background: Excessive daytime sleepiness (EDS) is a disabling symptom of Lewy body disorders (LBD). The hypothalamus is a key sleep-wake regulator and is involved in Lewy pathology, but its contribution to EDS in LBD rema...
Differences in Parkinson's Disease Populations: Teaching Hospitals Versus Other Settings and Implications for Clinical Trials [0.03%]
帕金森病患者在教学医院和非教学医院中的差异及其对临床试验的影响
Priti Gros,Connie Marras,Xuesong Wang et al.
Priti Gros et al.
Background: Parkinson disease (PD) disease-modifying therapy (DMT) trials generally recruit individuals from teaching hospitals. Whether these participants represent the broader PD population is unclear. ...