It Takes Guts: A Novel Model for Gut-to-Brain Propagation of Alpha-Synuclein and Tau [0.03%]
胆汁换脑:新型肠胃至大脑的α-突触核蛋白和tau病理性传播模型
Kasandra Scholz,Talene A Yacoubian
Kasandra Scholz
Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin-Sensitive Magnetic Resonance Imaging and 18F-Fluorodopa-Positron Emission Tomography [0.03%]
基于黑素神经成像和正电子发射断层扫描的纯自主功能衰竭的中枢参与:来自磁共振成像和18氟-FDOPA-正电子发射断层扫描的见解
Paula Trujillo,Kaitlyn R ORourke,Olivia C Roman et al.
Paula Trujillo et al.
Background: Central synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), involve alpha-synuclein accumulation and dopaminergic cell loss in the substan...
New Multiomic Studies Shed Light on Cellular Diversity and Neuronal Susceptibility in Parkinson's Disease [0.03%]
新的多组学研究揭示了帕金森病中的细胞多样性和神经元易感性
Marianna Liang,Linh Chu,Zhenyu Yue
Marianna Liang
Parkinson's disease is a complex neurodegenerative disorder characterized by degeneration of dopaminergic neurons, with patients manifesting varying motor and nonmotor symptoms. Previous studies using single-cell RNA sequencing in rodent mo...
Step Width Haptic Feedback for Gait Stability in Spinocerebellar Ataxia: Preliminary Results [0.03%]
脊髓小脑共济失调中步宽触觉反馈对步态稳定性的改善:初步结果
Hong Wang,Zakir Ullah,Eran Gazit et al.
Hong Wang et al.
Background: Wider step width and lower step-to-step variability are linked to improved gait stability and reduced fall risk. It is unclear if patients with spinocerebellar ataxia (SCA) can learn to adjust these aspects of...
Neutrophil-Rich Infusion Site Reactions After Continuous Subcutaneous Application of Foslevodopa/Foscarbidopa [0.03%]
富左旋多巴/富卡比多巴连续皮下输注的中性粒细胞型输注部位反应
David Weise,Sebastian Haferkamp
David Weise
Reply to: "Neutrophil-Rich Infusion Site Reactions after Continuous Subcutaneous Application of Foslevodopa/Foscarbidopa" [0.03%]
对“连续皮下注射foslevodopa/foscarbidopa后的中性粒细胞丰富型输注部位反应”的回复
Nagisa Yoshihara,Rei Watanabe,Noriko Nishikawa et al.
Nagisa Yoshihara et al.
Effect of a Wrist Harmonic Liquid Tremor Absorber-Damping on the Upper Extremity Essential Tremor [0.03%]
腕部谐波液体阻尼器对上肢特发性震颤的影响研究
Sultan Tarlacı,Furkan Doğan
Sultan Tarlacı
Background: Essential tremor (ET) is a common type of tremor. Previous research has shown that wearable orthoses and biomechanical loading methods can suppress tremors. ...
TDP-43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP-43 Proteinopathies [0.03%]
佩里综合征中TDP-43隐秘RNA:不同脑区及TDP-43蛋白病之间的差异
Sarah R Pickles,Jesus Gonzalez Bejarano,Anand Narayan et al.
Sarah R Pickles et al.
Background: Perry syndrome (PS) is a rare and fatal hereditary autosomal dominant neurodegenerative disorder caused by mutations in dynactin (DCTN1). PS brains accumulate inclusions positive for ubiquitin, transactive-res...
Anna Sadnicka,Mark J Edwards
Anna Sadnicka
Two Families with ANO10-Related Spinocerebellar Ataxia with Novel Exon Deletions: A First Report from India [0.03%]
两个与新型外显子缺失相关的ANO10家族性脊小脑共济失调家系报告:来自印度的首报
Vikram V Holla,Nitish Kamble,Reghunathan Sindhu Harishma et al.
Vikram V Holla et al.