Update on Treatments for Parkinson's Disease Motor Fluctuations - An International Parkinson and Movement Disorder Society Evidence-Based Medicine Review [0.03%]
帕金森病运动波动治疗进展 - 国际帕金森和运动障碍学会循证医学评论
Rob M A de Bie,Regina Katzenschlager,Bart E K S Swinnen et al.
Rob M A de Bie et al.
Objective: To update evidence-based medicine recommendations for treating motor fluctuations of Parkinson's disease (PD). Background: T...
Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells [0.03%]
17q21.31的拷贝数变异和单倍型分析揭示了进行性核上性麻痹的风险增加以及神经元细胞中的基因表达变化
Hui Wang,Timothy S Chang,Beth A Dombroski et al.
Hui Wang et al.
Background: The 17q21.31 region with various structural forms characterized by the H1/H2 haplotypes and three large copy number variations (CNVs) represents the strongest risk locus in progressive supranuclear palsy (PSP)...
Isolated Choreic Manifestations Indicative of Anti-Amphiphysin Antibody-Related Encephalitis in Breast Cancer [0.03%]
乳腺癌患者抗 Amphiphysin抗体相关性脑炎的孤立舞蹈症状表现
Stela Dodaj,Marie Rafiq,Raquel Barbosa et al.
Stela Dodaj et al.
Spinocerebellar Ataxia Progression Measured with the Patient-Reported Outcome Measure of Ataxia [0.03%]
共济失调患者报告结局量表对脊髓小脑共济失调进展的测量
Anna L Burt,Gilbert L&#x;Italien,Susan L Perlman et al.
Anna L Burt et al.
Background: The Patient-Reported Outcome Measure of Ataxia (PROM-Ataxia) has been validated cross-sectionally but not longitudinally. Objective: ...
Comparative Study of Focused Ultrasound Unilateral Thalamotomy and Subthalamotomy for Medication-Refractory Parkinson's Disease Tremor [0.03%]
超声聚焦丘脑切迹及底丘脑切迹术治疗药物难治性帕金森病震颤的对比研究
Steffen Paschen,Elena Natera-Villalba,José A Pineda-Pardo et al.
Steffen Paschen et al.
Background: Unilateral focused ultrasound ventral intermediate thalamotomy (Vim-FUS) is effective in treating Parkinson's disease (PD) tremor. Ultrasound ablation of the subthalamic nucleus (STN-FUS) has demonstrated effi...
Oscillatory Coupling Between Thalamus, Cerebellum, and Motor Cortex in Essential Tremor [0.03%]
原发性震颤中丘脑、小脑和运动皮层之间的振荡耦合
Alexandra Steina,Sarah Sure,Markus Butz et al.
Alexandra Steina et al.
Background: Essential tremor is hypothesized to emerge from synchronized oscillatory activity within the cerebello-thalamo-cortical circuit. However, this hypothesis has not yet been tested using local field potentials di...
Exploration of Neurodegenerative Diseases Using Long-Read Sequencing and Optical Genome Mapping Technologies [0.03%]
使用长读长测序和光学基因组图谱技术探索神经退行性疾病
Guillaume Cogan,Kensuke Daida,Cornelis Blauwendraat et al.
Guillaume Cogan et al.
Genetic factors play a central role in neurodegenerative disorders. Over the past few decades, significant progress has been made in identifying the causative genes of numerous monogenic disorders, largely due to the widespread adoption of ...
Beta Burst Characteristics and Coupling within the Sensorimotor Cortical-Subthalamic Nucleus Circuit Dynamically Relate to Bradykinesia in Parkinson's Disease [0.03%]
帕金森病中皮层-丘脑底核环路的贝塔暴发现象及其耦合与运动迟缓症状动态相关特性研究
Pan Yao,Abhinav Sharma,Bahman Abdi-Sargezeh et al.
Pan Yao et al.
Background: Bursts of exaggerated subthalamic nucleus (STN) beta activity are believed to contribute to clinical impairments in Parkinson's disease (PD). No previous studies have explored burst characteristics and couplin...
Thalamic Deep Brain Stimulation Versus Magnetic Resonance-Guided Focused Ultrasound in Tremor Patients: A Retrospective Single-Surgeon Comparison [0.03%]
丘脑深部脑刺激与磁共振引导的聚焦超声用于治疗震颤患者的对比：一项回顾性单手术者的比较研究
Christian Rainer Baumann,Andreas Fleisch,Sujitha Mahendran et al.
Christian Rainer Baumann et al.
Background: Bilateral deep brain stimulation (DBS) and unilateral magnetic resonance-guided focused ultrasound (MRgFUS), with potential future second-side treatment targeting the thalamic ventral intermediate nucleus (VIM...
Assessment of Piezo1 Expression in Urinary Exfoliated Cells as a Diagnostic Indicator for Multiple System Atrophy [0.03%]
尿液脱落细胞中Piezo1的表达作为多系统萎缩诊断指标的评估
Han Liu,Qingyong Zhu,Jiuqi Wang et al.
Han Liu et al.
Background: Multiple system atrophy (MSA) shares clinical features with idiopathic Parkinson' s disease (iPD) and progressive supranuclear palsy (PSP), yet reliable biomarkers for differential diagnosis remain elusive. ...