Auditory Stimulation of Slow-Wave Sleep Promotes Recovery after Brain Injury in an Animal Model [0.03%]
听觉刺激慢波睡眠可促进动物脑损伤模型的恢复
Carlos G Moreira,Adrian Müllner,Meltem Gönel et al.
Carlos G Moreira et al.
Objective: Traumatic brain injury (TBI) significantly reduces the quality of life for millions of survivors worldwide, causing persistent brain tissue damage and cognitive impairments, with no established therapeutic inte...
Brain Frailty Rather than Age Alone Mediates the Lack of Benefit for Endovascular Thrombectomy in the Elderly Population of the RESILIENT Trial [0.03%]
年龄相关性脑机能减退是导致RESILIENT试验中老年人群血管内血栓切除术效果不佳的中间因素，而非单纯高龄的影响
Rui Kleber do Vale Martins-Filho,Thiago Oscar Goulart,Octavio Marques Pontes-Neto et al.
Rui Kleber do Vale Martins-Filho et al.
Objective: The objective of this study was to determine whether baseline computed tomography (CT) markers of cerebral small vessel disease (cSVD), as a surrogate of brain frailty, explain the association between age and f...
Andrew Siderowf,Laura E A Heathers,Kimberly Fabrizio et al.
Andrew Siderowf et al.
The Parkinson's Progression Markers Initiative (PPMI) has remained at the vanguard of Parkinson's disease (PD) research through evolving recruitment strategies that mirror advances in PD biology. PPMI was initially focused on untreated, ear...
Editorial
Annals of neurology. 2026 May 10. DOI:10.1002/ana.78239 2026
Expanding PPMI through Remote Data Acquisition and Analysis: Early Success and Future Growth with myPPMI [0.03%]
帕金森病进展倡议（PPMI）远程数据采集与分析项目：myPPMI的早期成功及未来展望
Caroline M Tanner,Craig E Stanley,Ethan G Brown et al.
Caroline M Tanner et al.
The creation and ongoing development of the myPPMI platform (see Stanley et al in this issue), has enabled the Parkinson's Progression Markers Initiative (PPMI) to expand our research efforts to acquire additional data, engage a large numbe...
Editorial
Annals of neurology. 2026 May 10. DOI:10.1002/ana.78245 2026
Andrew Y Revell,Marc Jaskir,Akash R Pattnaik et al.
Andrew Y Revell et al.
Objective: The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure anal...
Cerebrospinal Fluid-Mediated Dissemination in Balamuthia mandrillaris Amebic Encephalitis [0.03%]
鲍曼阿米巴脑炎中脑脊液介导的 dissemination 现象
Shaoping Zhong,Jin Liu,Jianying Liu et al.
Shaoping Zhong et al.
Pies in the Sky [0.03%]
空中楼阁
Shivangi D Pandya,Bernard P L Chan,Vijay K Sharma
Shivangi D Pandya
How PPMI Enabled the First Interventional Platform Trial to Test Therapies in Participants With Early-Stage Neuronal Alpha-Synuclein Disease [0.03%]
PPMI如何助力首个在早期神经原性α-突触核蛋白病参与者中测试疗法的干预平台试验
Tanya Simuni,Christopher S Coffey,Catherine M Kopil et al.
Tanya Simuni et al.
The Path to Prevention (P2P) platform trial is a multicenter, multi-regimen, proof of concept, phase 2A, randomized clinical trial evaluating the safety and early efficacy of investigational products for the treatment of early-stage Neurona...
Editorial
Annals of neurology. 2026 May 7. DOI:10.1002/ana.78250 2026
Diffusion MRI and α-Synuclein Seed Amplification Status in Parkinson's Disease [0.03%]
帕金森病中弥散张量成像和α-突触核蛋白种子放大状态的关系
Shannon Y Chiu,Wei-En Wang,Robin Chen et al.
Shannon Y Chiu et al.
Objective: Positive α-synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free-water (FW) imaging detects microstructural differences in the brains o...
Kenneth Marek,Thomas F Tropea
Kenneth Marek
Editorial
Annals of neurology. 2026 May 6. DOI:10.1002/ana.78244 2026