Alexander C Ford,Paul Moayyedi
Alexander C Ford
Purpose of review: Dyspepsia affects up to 40% of the general population and significantly reduces quality of life. A small proportion of patients have peptic ulcer disease as cause and this can be treated empirically wit...
Helicobacter pylori infection: selected aspects in clinical management [0.03%]
Helicobacter pylori感染:临床处理的几个方面
Peter Malfertheiner,Marino Venerito,Michael Selgrad
Peter Malfertheiner
Purpose of review: This review focuses on new aspects of recently published guidelines for the management of Helicobacter pylori infection as well as progress in diagnostic tests and treatment regimens. We also discuss ne...
Thomas Kemmerly,Jonathan D Kaunitz
Thomas Kemmerly
Purpose of review: To review recent developments in the field of gastroduodenal mucosal defense. Recent findings: Research in the field...
Neena S Abraham,Diana L Castillo
Neena S Abraham
Purpose of review: To quantify the novel oral anticoagulant (NOAC)-related gastrointestinal bleeding, summarize the management strategies and highlight the knowledge gaps. ...
The tumor necrosis factor-like cytokine 1A/death receptor 3 cytokine system in intestinal inflammation [0.03%]
细胞因子系统在肠道炎症中的作用
Giorgos Bamias,Li-Guo Jia,Fabio Cominelli
Giorgos Bamias
Purpose of review: Tumor necrosis factor (TNF)-like cytokine 1A (TL1A) associates with the death receptor 3 (DR3) on activated lymphocytes and induces proinflammatory signals. The decoy receptor 3 (DcR3) competes for TL1A...
Suzanne Devkota,Eugene B Chang
Suzanne Devkota
Purpose of review: To present and evaluate the recent findings that contribute to our understanding of the functional impact of diet on the enteric microbiome and outcomes of disease. ...
Advances in therapeutic interventions targeting the vascular and lymphatic endothelium in inflammatory bowel disease [0.03%]
针对炎症性肠病的血管和淋巴内皮治疗干预研究进展
Silvia DAlessio,Carlotta Tacconi,Claudio Fiocchi et al.
Silvia DAlessio et al.
Purpose of review: The review summarizes the current knowledge of the roles played by the vascular and lymphatic endothelium throughout the gut in the pathogenesis of inflammatory bowel disease (IBD) and gives an update o...
Molecular signatures for the dynamic process of establishing intestinal host-microbial homeostasis: potential for disease diagnostics? [0.03%]
建立肠道宿主-微生物稳态的动态过程的分子标志物:疾病诊断的潜力?
Sahar El Aidy,Michiel Kleerebezem
Sahar El Aidy
Purpose of review: The dynamic interplay of the intestinal microbiota and host has been the focus of many studies because of its impact on the health status in human life. Recent reports on the time-resolved immune and me...
Jakob Begun,Ramnik J Xavier
Jakob Begun
Purpose of review: From its initial description as a homeostatic process required for starvation response, autophagy has emerged as a ubiquitous cellular process involved in a broad range of cellular activities from metab...
Innate lymphoid cells in homeostasis, infection, chronic inflammation and tumors of the gastrointestinal tract [0.03%]
肠道稳态、感染、慢性炎症和肿瘤中的固有淋巴细胞
Anja Fuchs,Marco Colonna
Anja Fuchs
Purpose of review: To highlight the functions of a recently discovered group of immune cells known as innate lymphoid cells (ILCs) during homeostasis and infections of the gastrointestinal tract. ...