Mechanistic insights into pancreatic duct pressure: from basic physiology to translational implications [0.03%]
胰管压力的机制研究：从基础生理学到转化意义
Jianing Li,Li Wen,Aiming Yang
Jianing Li
Purpose of review: This review summarizes recent advances in pancreatic ductal hypertension (PDH), emphasizing its pathophysiological mechanisms, clinical relevance across pancreatic diseases, and progress in noninvasive ...
Management of autoimmune hepatitis-related decompensated cirrhosis: current evidence and clinical decision-making [0.03%]
自身免疫性肝炎相关失代偿期肝硬化的管理：现有证据和临床决策
Pinelopi Arvaniti,Maria-Carlota Londoño
Pinelopi Arvaniti
Purpose of review: Autoimmune hepatitis (AIH) presenting with decompensated cirrhosis poses a major therapeutic dilemma for clinicians. Although the prompt initiation of immunosuppression (IS) can reverse disease activity...
Anna Palmiotti,Anna Bertolini,Romina Fiorotto
Anna Palmiotti
Purpose of review: Cystic fibrosis liver disease (CFLD) is a significant nonpulmonary complication of cystic fibrosis, affecting approximately 5-10% of patients. It encompasses a spectrum of hepatic abnormalities ranging ...
Clinical management and outcomes of hepatobiliary disease in the cystic fibrosis transmembrane conductance regulator modulator era [0.03%]
囊性纤维化跨膜传导调节剂时代肝胆病的临床管理及转归
Carolena Trocchia,Lauren Lazar,Zachary M Sellers
Carolena Trocchia
Purpose of review: Multiple cystic fibrosis transmembrane conductance regulator (CFTR) modulators are approved for the treatment of cystic fibrosis (CF) and show significant improvement in lung function, BMI, quality of l...
PBC-AIH variant syndrome: emerging new terminology and a new approach to diagnosis and management [0.03%]
PBC-AIH变异综合征：新术语的出现及诊断和治疗的新方法
Marcial Sebode,Alessio Gerussi
Marcial Sebode
Purpose of review: This review summarizes the recent developments of one of the most controversial entities in hepatology, variant syndromes of primary biliary cholangitis (PBC) with characteristics of autoimmune hepatiti...
Anusha Shirwaikar Thomas
Anusha Shirwaikar Thomas
Minimally invasive, maximum impact: advances in the application of colonic stents [0.03%]
微创最大效益：结肠支架应用进展
Filippos Koutroumpakis,Emmanuel Coronel
Filippos Koutroumpakis
Purpose of review: Malignant colorectal obstruction (MCO) is a common and life-threatening presentation of colorectal cancer, traditionally managed with emergency surgery associated with high morbidity and high stoma rate...
Malek Shatila,Yinghong Wang,Anusha Shirwaikar Thomas
Malek Shatila
Purpose of review: Immune-mediated diarrhea and colitis (IMDC) is a very common and severe toxicity to immune checkpoint inhibition that has generated a lot of scientific interest. The current guidelines do not capture th...
All in my head or all in my gut? An update on irritable bowel syndrome [0.03%]
一切都在我的脑海里还是肠道里？关于肠易激综合征的最新研究进展
Amy T Woods,Alexander C Ford,Christopher J Black
Amy T Woods
Purpose of review: Irritable bowel syndrome (IBS) has a considerable impact on patients and healthcare systems. IBS is a disorder of brain-gut interaction with numerous biopsychosocial factors involved, including early li...
Endoscopic mucosal resection or endoscopic submucosal dissection: choosing the right tool to a polyp-free colon [0.03%]
内镜下黏膜切除还是内镜下黏膜剥离：打造无蒂息肉结肠策略的选择
George M Wahba,Fredy Nehme,Phillip S Ge
George M Wahba
Purpose of review: Endoscopic resection is now the standard of care for the management of colorectal polyps. With increased training and expertise in endoscopic mucosal resection (EMR) and endoscopic submucosal dissection...