Kevin P Murphy,Patrick D McLaughlin,Owen J OConnor et al.
Kevin P Murphy et al.
Purpose of review: Radiologic investigations continue to play a pivotal role in the diagnosis of pathologic conditions of the small intestine despite enhancement of capsule endoscopy and double-balloon endoscopy. Imaging ...
New approaches to the treatments of short bowel syndrome-associated intestinal failure [0.03%]
短肠综合征相关性肠道功能衰竭的治疗新策略
Palle B Jeppesen
Palle B Jeppesen
Purpose of review: Teduglutide, a recombinant analog of human glucagon-like peptide 2, has recently been approved in the US and Europe (Gattex and Revestive, respectively) as the first targeted treatment of short bowel sy...
Eamonn M M Quigley
Eamonn M M Quigley
Purpose of review: To critically review recent literature on small intestinal bacterial overgrowth (SIBO). Recent findings: When origin...
Thomas C Darton,Christoph J Blohmke,Andrew J Pollard
Thomas C Darton
Purpose of review: Infection caused by ingestion of human-restricted Salmonella enterica serovars Typhi and Paratyphi predominantly affects the most impoverished sections of society. In this review, we describe recent adv...
The multiple roles of guanylate cyclase C, a heat stable enterotoxin receptor [0.03%]
鸟苷酸环化酶C的多重作用,一种热稳定肠毒素受体
Kris A Steinbrecher
Kris A Steinbrecher
Purpose of review: Guanylate cyclase C (GC-C) is a transmembrane receptor that is expressed primarily on intestinal epithelial cells. Activation of this receptor by its endogenous peptide ligands initiates cyclic guanosin...
Wojciech Blonski,Anna M Buchner,Gary R Lichtenstein
Wojciech Blonski
Purpose of review: Ulcerative colitis is a chronic inflammatory disease of the colon of unknown cause that is characterized by alternating intervals of active and inactive disease in 80-90% of patients. The primary goal o...
Hitoshi Honda,Erik R Dubberke
Hitoshi Honda
Purpose of review: Clostridium difficile infection (CDI) is a growing concern and has a substantial impact on morbidity and mortality. Epidemiology of CDI has dramatically changed over the last decade. Diagnostic and trea...
Emerging infectious colitis [0.03%]
新兴感染性结肠炎
Nejma Aboutaleb,Edward J Kuijper,Jaap T van Dissel
Nejma Aboutaleb
Purpose of review: The present review will highlight recent advances in the knowledge of emerging pathogens causing infectious colitis and provide a description of the most important food-borne outbreaks. ...
Fecal microbiota transplantation for Clostridium difficile infection: benefits and barriers [0.03%]
艰难梭菌感染的粪便微生物移植:益处与障碍
Andrea Lo Vecchio,Mitchell B Cohen
Andrea Lo Vecchio
Purpose of review: The incidence and severity of Clostridium difficile infection (CDI) have increased worldwide in the past two decades. A principal function of the gut microbiota is to protect the intestine against colon...
Vineet S Gudsoorkar,Eamonn M M Quigley
Vineet S Gudsoorkar
Purpose of review: To critically evaluate recent advances in the anatomy and physiology of colorectal motility and sensation and to discuss their potential clinical implications. ...