Glucagon like peptide-1 receptor agonists as a promising therapeutic option of metabolic dysfunction associated steatotic liver disease and obesity: hitting two targets with one shot [0.03%]
胰高血糖素样肽-1受体激动剂作为代谢功能障碍相关脂肪性肝病和肥胖的有希望的治疗选择：一石二鸟
Eda Kaya,Wing-Kin Syn,Paul Manka
Eda Kaya
Purpose of review: Obesity and type 2 diabetes mellitus (T2DM) are significant global health challenges, closely linked to metabolic dysfunction-associated steatotic liver disease (MASLD). Glucagon-like peptide-1 receptor...
The clinical challenge of managing patients after sustained virological response with direct-acting antivirals for Hepatitis C [0.03%]
直接抗病毒药物对丙型肝炎持续病毒学反应患者的管理临床挑战
Anna Pocurull,Sabela Lens
Anna Pocurull
Purpose of review: This review highlights the critical considerations for monitoring patients who achieve sustained virological response (SVR) after direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infect...
Small bowel vasculitis? what a gastroenterologist should know - from diagnosis to management [0.03%]
小肠血管炎？胃肠病专家应知的从诊断到管理的所有知识
João Carlos Gonçalves,Bruno Rosa,José Cotter
João Carlos Gonçalves
Purpose of review: This article provides gastroenterologists with an overview of small bowel involvement in systemic vasculitis. Though various vasculitides can impact the small bowel, we highlight those with a more frequ...
Panenteric capsule endoscopy in gastrointestinal bleeding - time to change old habits? [0.03%]
全小肠胶囊内镜在消化道出血的应用- 是否到了改变旧习惯的时候？
Francesco Segatta,Silvia Paggi,Franco Radaelli et al.
Francesco Segatta et al.
Purpose of review: Capsule endoscopy (CE) is an effective tool for small bowel evaluation. Recent technical advancements, including long-lasting batteries and enhanced optics, have enabled featured capsules (panenteric ca...
Individualizing the choice of surgical therapy for gastroesophageal reflux disease [0.03%]
个体化选择抗反流手术方法
Luigi Bonavina
Luigi Bonavina
Purpose of review: Proton-pump inhibitor therapy does not provide complete relief of symptoms in up to 40% of patients with gastroesophageal reflux disease (GERD). Antireflux surgery (ARS) aims to reconstruct the natural ...
Antonella Santonicola,Carlo Soldaini,Carolina Ciacci
Antonella Santonicola
Purpose of review: Celiac disease (CeD) is a chronic autoimmune disorder of the small intestine triggered by gluten ingestion in genetically predisposed individuals. The cornerstone of CeD management remains a strict adhe...
Assessing patient-reported outcomes in primary sclerosing cholangitis: an update [0.03%]
原发性硬化性胆管炎患者报告结局的评估：更新版
Donna M Evon,Bryce B Reeve
Donna M Evon
Purpose of review: Patient-reported outcome (PRO) measures validated in primary sclerosing cholangitis (PSC) are needed for clinical trials. This review describes the recent US Food & Drug Administration (FDA) Patient-Foc...
The impact of deep response to ursodeoxycholic acid in primary biliary cholangitis - should it be the new clinical standard? [0.03%]
熊去氧胆酸在原发性胆汁性肝病深度反应的影响-应成为新的临床标准吗？
Adrielly Martins,Cynthia Levy
Adrielly Martins
Purpose of review: This review explores the emerging concept of "deep response" in primary biliary cholangitis (PBC), defined by the normalization of biochemical markers, particularly alkaline phosphatase and bilirubin. I...
Current approach to diagnosis and management of low-phospholipid associated cholelithiasis syndrome [0.03%]
低磷脂性胆石症的诊断和治疗策略
Pierre-Antoine Soret,Olivier Chazouillères,Christophe Corpechot
Pierre-Antoine Soret
Purpose of review: Low phospholipid-associated cholelithiasis (LPAC) syndrome is a rare genetic form of intrahepatic cholesterol lithiasis, affecting mainly young adults. This review describes the recent advances in genet...
Effect of low birth weight and preterm delivery on the development of childhood celiac disease: a systematic review and meta-analysis on observational studies [0.03%]
低体重和早产对儿童乳糜泻发病的影响：观察性研究的系统评价和meta分析
Mansour Bahardoust,Ali Delpisheh,Shabnam Rashidi et al.
Mansour Bahardoust et al.
Purpose of review: Whether low birth weight (LBW) and preterm delivery (PD) are associated with the risk of developing celiac disease (CD) in children remains unclear. This systematic review and meta-analysis aimed to eva...