Jad Allam,Don C Rockey
Jad Allam
Purpose of review: No universal consensus exists as to what the upper limit of normal for alanine aminotransferase (ALT) should be. The purpose of this review is to provide insight on the wide variation in the upper limit...
Austin D Peer,Jennifer C Price
Austin D Peer
Purpose of review: Despite the efficacy of direct-acting antiviral (DAA) therapy, hepatitis C virus (HCV) remains a significant contributor to liver-related morbidity and mortality. This review summarizes the approach to ...
Who and how to choose combination therapy for inflammatory bowel disease: a comprehensive expert review [0.03%]
炎症性肠病的联合治疗如何选择及如何实施：全面专家回顾
Alessandro David,Chakib Rekkabi,Annissa Fournier et al.
Alessandro David et al.
Purpose of review: Therapeutic options in inflammatory bowel disease (IBD) have expanded significantly. Patients often experience primary or secondary loss of response to biologics or small molecules therapy. Determining ...
Kimberley Butler,Thomas Peachey,Reena Sidhu et al.
Kimberley Butler et al.
Purpose of review: Meckel's diverticulum (MD) is a common congenital ileal diverticulum. Whilst mostly asymptomatic, 4-9% develop complications, such as small bowel obstruction, diverticulitis or bleeding. In 1933, Charle...
Dorien Pint,Yooyun Chung,Michael A Heneghan
Dorien Pint
Purpose of review: This review highlights the management, maternal and fetal outcomes, and the critical role of prepregnancy counseling for women with portal hypertension (PHT), a topic of growing clinical relevance as pr...
The role of gluten and wheat in irritable bowel syndrome and noncoeliac gluten or wheat sensitivity [0.03%]
麸质和小麦在肠易激综合症及非乳糜泻性麸质或小麦敏感中的作用
Tom van Gils,Magnus Simrén
Tom van Gils
Purpose of review: The role of gluten and wheat in irritable bowel syndrome (IBS) is unclear, whereas it plays a key-role in the diagnosis and treatment of noncoeliac gluten or wheat sensitivity (NCGWS). This review aims ...
Contemporary management of portal vein thromboses in patients with and without cirrhosis [0.03%]
伴有和不伴有肝硬化的门静脉血栓的现代管理方法
Abhishek Shenoy,Jessica P E Davis
Abhishek Shenoy
Purpose of review: Portal vein thromboses (PVT) is a common clotting disorder that can be seen in patients with and without cirrhosis. There are no current clinical guidelines on management of portal vein thromboses in th...
James Wild,Nicoletta Nandi,Thean Soon Chew et al.
James Wild et al.
Purpose of review: Crohn's disease (CD), requires accurate diagnosis and regular monitoring to manage disease activity, prevent complications, and improve outcomes. Intestinal ultrasound (IUS) has emerged as a noninvasive...