Assessing patient-reported outcomes in primary sclerosing cholangitis: an update [0.03%]
原发性硬化性胆管炎患者报告结局的评估：更新版
Donna M Evon,Bryce B Reeve
Donna M Evon
Purpose of review: Patient-reported outcome (PRO) measures validated in primary sclerosing cholangitis (PSC) are needed for clinical trials. This review describes the recent US Food & Drug Administration (FDA) Patient-Foc...
The impact of deep response to ursodeoxycholic acid in primary biliary cholangitis - should it be the new clinical standard? [0.03%]
熊去氧胆酸在原发性胆汁性肝病深度反应的影响-应成为新的临床标准吗？
Adrielly Martins,Cynthia Levy
Adrielly Martins
Purpose of review: This review explores the emerging concept of "deep response" in primary biliary cholangitis (PBC), defined by the normalization of biochemical markers, particularly alkaline phosphatase and bilirubin. I...
Current approach to diagnosis and management of low-phospholipid associated cholelithiasis syndrome [0.03%]
低磷脂性胆石症的诊断和治疗策略
Pierre-Antoine Soret,Olivier Chazouillères,Christophe Corpechot
Pierre-Antoine Soret
Purpose of review: Low phospholipid-associated cholelithiasis (LPAC) syndrome is a rare genetic form of intrahepatic cholesterol lithiasis, affecting mainly young adults. This review describes the recent advances in genet...
Effect of low birth weight and preterm delivery on the development of childhood celiac disease: a systematic review and meta-analysis on observational studies [0.03%]
低体重和早产对儿童乳糜泻发病的影响：观察性研究的系统评价和meta分析
Mansour Bahardoust,Ali Delpisheh,Shabnam Rashidi et al.
Mansour Bahardoust et al.
Purpose of review: Whether low birth weight (LBW) and preterm delivery (PD) are associated with the risk of developing celiac disease (CD) in children remains unclear. This systematic review and meta-analysis aimed to eva...
Hepatic metabolism and ketone production in metabolic dysfunction-associated steatotic liver disease [0.03%]
与代谢功能障碍相关脂肪肝的肝脏代谢及酮体生成
Eric P Plaisance
Eric P Plaisance
Purpose of review: Metabolic dysfunction-associated steatotic liver disease (MASLD) is present in 25-35% of individuals in the United States. The purpose of this review is to provide the contextual framework for hepatic k...
Ines B Moura,Anthony M Buckley
Ines B Moura
Purpose of review: Antibiotics are a cornerstone of modern medicine, but antibiotic consumption can have depleting effects on the gut microbiota, potentially leading to gastrointestinal symptoms and other diseases, namely...
Charlotte Yeung,Laura E McCoubrey,Abdul W Basit
Charlotte Yeung
Purpose of review: Herein, we present an overview of innovative oral technologies utilized in colonic drug delivery systems that have made significant translational and clinical advancements to treat inflammatory bowel di...
Russell D Cohen
Russell D Cohen
Prabin Sharma,Stavros N Stavropoulos
Prabin Sharma
Purpose of review: We will review the current management of colonic perforations, with particular emphasis on iatrogenic perforations caused by colonoscopy, the leading etiology. We will focus on recently developed endosc...