Grégory Merlen,Thierry Tordjmann
Grégory Merlen
Purpose of review: In the pathophysiological context of cholangiopathies and more broadly of hepatopathies, while it is conceptually clear that the maintenance of inter-cholangiocyte and inter-hepatocyte tight junction in...
David C Trampert,Roni F Kunst,Stan F J van de Graaf
David C Trampert
Purpose of review: Advances in the understanding of bile salt synthesis, transport and signalling show the potential of modulating bile salt homeostasis as a therapeutic strategy in cholestatic liver diseases. Here, recen...
Nutritional deficiencies in alcohol use disorder/alcohol-associated liver disease [0.03%]
酒精使用障碍/酒精相关肝病中的营养缺乏问题
Loretta Jophlin,Tzu-Yu Liu,Craig J McClain
Loretta Jophlin
Purpose of review: To delineate common and uncommon dietary and nutritional deficiencies in individuals with chronic heavy alcohol use and alcohol use disorder and to highlight important advances in the nutrition field in...
Micronutrient status and protein-energy malnutrition in free-living older adults: a current perspective [0.03%]
自由生活老年人的微量营养素状况和蛋白质能量营养不良：当前观点
Maria Del Carmen Alvarez-Nuncio,Thomas R Ziegler
Maria Del Carmen Alvarez-Nuncio
Purpose of review: This review addresses the newest findings on micronutrient status and protein-energy malnutrition in the increasingly aging global population; understanding the nutritional challenges they face is vital...
Nicole Sciberras,Stefania Chetcuti Zammit,Reena Sidhu
Nicole Sciberras
Purpose of review: Adult small bowel intussusception (SBI) differs in incidence, symptomatology and management from the more commonly encountered paediatric intussusception. This review spans across the multitude of cause...
Kevin De Muynck,Lindsey Devisscher
Kevin De Muynck
Purpose of review: Primary sclerosing cholangitis is a chronic cholestatic liver disease for which no pharmacological treatment options are available. It is an immune-mediated disease and macrophages have been implicated ...
Mohamed G Shiha,David S Sanders,Reena Sidhu
Mohamed G Shiha
Purpose of review: Quality indicators for upper and lower gastrointestinal endoscopy are well established and linked to patient outcomes. However, there is a perceived gap in the development and implementation of quality ...
Farhana Ali,Marialena Mouzaki
Farhana Ali
Purpose of review: The purpose of this review is to summarize commonly encountered nutritional deficiencies in children and their implications. Considering data suggesting that the majority of children with the United Sta...
Johanna R Schaub,Jennifer Y Chen,Scott M Turner
Johanna R Schaub
Purpose of review: Current treatment options for cholangiopathies are severely limited and there is thus a critical need to identify and develop therapies. This review discusses the role of integrins in biliary injury and...
Yotam Elimeleh,Ian M Gralnek
Yotam Elimeleh
Purpose of review: We review and summarize the most recent literature, including evidence-based guidelines, on the evaluation and management of acute lower gastrointestinal bleeding (LGIB). ...