The role of the fibroblast in Barrett's esophagus and esophageal adenocarcinoma [0.03%]
纤维母细胞在巴雷特食管和食管腺癌中的作用
Huili Zhu,Ramon U Jin
Huili Zhu
Purpose of review: Barrett's esophagus (BE) is the number one risk factor for developing esophageal adenocarcinoma (EAC), a deadly cancer with limited treatment options that has been increasing in incidence in the US. In ...
Vincent Bos,Man Wai Chan,Roos E Pouw
Vincent Bos
Purpose of review: This review aims to discuss recent advancements in the endoscopic management of early esophageal adenocarcinoma (T1 EAC). Recent findin...
Elizabeth A Scoville,Sara N Horst
Elizabeth A Scoville
Purpose of review: This review details the three new agents, including two novel mechanisms of action, approved to treat Crohn's disease in recent years. We review efficacy, safety, prescribing information, and available ...
Tara Nagaraj,John Shinn,Kara De Felice
Tara Nagaraj
Purpose of review: Several new biologics (mirizikizumab) and small molecules (upadacitinib, ozanimod, etrasimod) are approved for the treatment of moderate-to-severe ulcerative colitis. To date, there are no head-to-head ...
Yasutoshi Shiratori,Syed Matthew Kodilinye,Ahmed E Salem
Yasutoshi Shiratori
Purpose of review: This review is focused on diagnostic and management strategies for colonic diverticular bleeding (CDB). It aims to present the current state of the field, highlighting the available techniques, and emph...
Reena Sidhu
Reena Sidhu
Andres Duarte-Rojo,Keyur Patel,Don C Rockey
Andres Duarte-Rojo
Purpose of review: The result of ongoing liver injury - and disease, regardless of cause - is fibrosis, and fibrosis appears to be a critically important result of ongoing injury. Further, in a number of different liver d...
Jessica Elizabeth Smith,Don C Rockey
Jessica Elizabeth Smith
Purpose of review: Ischemic hepatitis (IH) refers to diffuse liver injury secondary to hypoperfusion. The condition is usually seen in the critical care setting and is associated with significant mortality. IH typically o...
Suneil A Raju,Mohamed G Shiha,Hugo A Penny
Suneil A Raju
Purpose of review: Persistent villous atrophy is associated with morbidity in coeliac disease and most commonly due to ongoing gluten ingestion. Current methods for assessing gluten exposure and persisting villous atrophy...
Mast cell activation and nutritional disorders in patients with hypermobility [0.03%]
高运动度患者中肥大细胞活化和营养失调的关系
Hugo A Penny,Imran Aziz,Ching Lam
Hugo A Penny
Purpose of review: Individuals with joint hypermobility disorders are increasingly referred to gastroenterology services for support with the investigation and management of gastrointestinal complaints. Individuals can pr...