Myeloproliferative neoplasms in the young: unique disease patterns and therapeutic strategies [0.03%]
年轻患者的骨髓增生性肿瘤：独特的疾病模式和治疗策略
Aarya Murali,James T England,Dawn Maze
Aarya Murali
Purpose of review: 10-20% of myeloproliferative neoplasms (MPNs) are diagnosed in adolescent and young adult (AYA) patients. This review aims to summarize current literature on AYA MPN, to highlight unique clinico-patholo...
Contemporary data in myeloproliferative neoplasm-unclassifiable: mutational landscape and management of the 'unclassifiable' [0.03%]
不能分类的骨髓增生性肿瘤（MPN）的目前数据：分子图谱和“不能分类”患者的管理策略
Artem Oganesyan,Rafael Madero-Marroquin,Anand A Patel
Artem Oganesyan
Purpose of review: Myeloproliferative neoplasm-unclassifiable (MPN-U) is a heterogenous subtype of Philadelphia-chromosome negative (Ph-) MPN that comprises 5-20% of Ph- MPN cases. Given the clinical and molecular variabi...
Navigating prognostic stratification and approach to TP53-mutated myeloid neoplasms [0.03%]
TP53突变型髓系肿瘤的预后分层和治疗策略(IF=160)
Talha Badar,Ayalew Tefferi,Naseema Gangat
Talha Badar
Purpose of review: TP53-mutated (TP53-MT) myeloid neoplasms (MN) represent one of the most challenging disease subsets due to their distinct pathobiology, frequent association with therapy-related disease, chemo-resistant...
Platelet concentrates in periodontics: a journey through platelet-rich plasma, platelet-rich fibrin and their therapeutic uses: a literature update [0.03%]
口腔种植领域浓缩血小板制品的研究进展：富血小板纤维蛋白与富血小板血浆的区别及临床应用更新
Supreet Kaur,Priyanka Saluja,Suheel Manzoor Baba et al.
Supreet Kaur et al.
Purpose of review: This review aims to provide an updated overview of platelet concentrates, particularly platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), and their evolving applications in periodontal therapy. ...
Limitations of rituximab in treating primary immune thrombocytopenia and the therapeutic potentials of alternatives [0.03%]
利妥昔单抗治疗原发性免疫性血小板减少症的局限性及其替代疗法的发展潜力
Lingxiao Pan,Jianfeng Zhu
Lingxiao Pan
Purpose of review: Primary immune thrombocytopenia (ITP), an immune-mediated hemorrhagic disease, features an intricate pathogenesis that involves megakaryocyte malfunction and hyperresponsiveness of the innate and adapti...
Mariia Naumenko,Nadezhda Podoplelova,Anna Wieland-Greguare-Sander et al.
Mariia Naumenko et al.
Purpose of review: Optimized platelet isolation is essential for preserving platelet integrity and function. This review elucidates the scientific rationale behind common workflows, explores modern strategies for their re...
Cellular contributions to the pathogenesis of anti-platelet factor 4 disorders [0.03%]
细胞在抗血小板第四因子疾病发病机制中的作用
Jared Treverton,Mark Lychacz,Donald M Arnold et al.
Jared Treverton et al.
Purpose of review: Anti-platelet factor 4 (PF4) disorders, including heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombocytopenia and thrombosis (VITT), and emerging disorders such as VITT-like monoc...
Proteomic perspectives on platelet reactivity: towards precision thrombosis research [0.03%]
基于蛋白质组学的血小板活性研究——向精准血栓病学研究迈进
Joseph E Aslan
Joseph E Aslan
Purpose of review: Advances in proteomics continue to expand our understanding of how protein systems regulate platelet function in hemostasis, thrombosis, and inflammation. However, clinical translation of platelet prote...