Combined molecular mismatch scores for immunologic risk stratification in pediatric heart transplantation [0.03%]
儿童心脏移植的免疫风险分层的综合分子错配评分
Mitchell A Ellison,Qingyong Xu,Adriana Zeevi
Mitchell A Ellison
Purpose of review: This article will review the use of HLA molecular mismatch algorithms to predict the risk of de-novo DSA and rejection in pediatric heart transplant recipients. Here, we will focus on results obtained u...
Hypothermic oxygenated perfusion: cellular mechanisms and clinical outcomes [0.03%]
低温氧合灌注：细胞机制及临床效果
Fatma Selin Yildirim,Keyue Sun,Sangeeta Satish et al.
Fatma Selin Yildirim et al.
Purpose: Machine perfusion has emerged as a transformative technique in organ transplantation, helping to address the persistent organ shortage while mitigating ischemia-reperfusion injury. Since the 2010s, its implementa...
Jenny N Tran,James H Lan
Jenny N Tran
Purpose of review: Current immune risk criteria for selecting induction therapy lack precision. Here, we examined the relationship of human leukocyte antigen (HLA) and molecular matching with outcomes in patients treated ...
Kathy L Coffman
Kathy L Coffman
Purpose of review: Transplantation in candidates with psychotic disorders has been a controversial topic for over 40 years. Reviewing the outcomes of these candidates may inform decisions going forward, though it is uncle...
Bettina M Buchholz,Uta Herden,Ania C Muntau et al.
Bettina M Buchholz et al.
Purpose of review: Liver transplantation using pediatric and technical variant grafts presents unique challenges due to graft size, vascular anomalies, and ischemia-reperfusion injury. Static cold storage has been the sta...
Mesenchymal stem cell therapy against ischemia-reperfusion injury in lung transplantation [0.03%]
间充质干细胞在肺移植缺血再灌注损伤治疗中的作用
Ichiro Sakanoue,Daisuke Nakajima
Ichiro Sakanoue
Purpose of review: Ischemia-reperfusion injury (IRI) remains a major challenge in lung transplantation, contributing to early graft dysfunction and negatively affecting long-term outcomes. This review highlights recent ad...
Forging a path toward kidney transplant equity through multilevel interventions [0.03%]
多层次干预推动肾脏移植公平性路径建设
Dinushika Mohottige,Clarissa J Diamantidis,Tanjala S Purnell et al.
Dinushika Mohottige et al.
Purpose of review: Persistent disparities in access to kidney transplantation, particularly living donor transplant and preemptive transplant, have gained increasing national attention including efforts to describe their ...
Erin Yu,Baddr A Shakhsheer,Sean C Wightman
Erin Yu
Purpose of review: This paper explores the ethical complexities of surgical buy-in within the context of organ transplantation. Surgical buy-in refers to an implicit agreement in which transplant recipients consent not on...
Ethics of deceased organ donation and normothermic regional perfusion: donors are 'dead enough' [0.03%]
有关供体器官捐献和灌注的伦理问题：“够死”即可
Hector C Ramos,Emily Beers
Hector C Ramos
Purpose of review: Normothermic regional perfusion (NRP) for the donation after circulatory death (DCD) increases the supply and function of organs. However, the procedures used have led to significant ethical controversi...
Epithelial-immune crosstalk in lung transplant ischemia-reperfusion injury [0.03%]
肺移植缺血再灌注损伤中的上皮-免疫相互作用
Annika Schmidt,Daniel R Calabrese
Annika Schmidt
Purpose of review: This review examines the epithelial-immune crosstalk in lung transplant ischemia-reperfusion injury (IRI). IRI is the mechanism underpinning primary graft dysfunction (PGD), a clinical syndrome that occ...