Nicola Dalbeth,Lisa K Stamp
Nicola Dalbeth
Purpose of review: Erosive gout refers to the presence of at least one gouty bone erosion in a person with gout. This review provides an update on the update on mechanisms, impact, and treatment of erosive gout. ...
Type I interferonopathies: 15 years after the concept-news and views [0.03%]
I型干扰素opathy:概念提出后的15年-新闻与观点
Samira Khaldi-Plassart,Isabelle Melki,Marie-Louise Frémond
Samira Khaldi-Plassart
Purpose of review: Genetic autoinflammatory conditions constitute an increasing field. Among them, type I interferonopathies (IFNp-I) were conceptualized 15 years ago as inborn errors of immunity due to chronic activation...
Kathie Velez,Grace A Osborne,Allison C Billi
Kathie Velez
Purpose of review: Cutaneous lupus erythematosus (CLE) is a heterogeneous inflammatory skin disease that can be disfiguring and profoundly affect patient quality of life. CLE is frequently challenging to manage and may re...
"Updates in chronic nonbacterial osteomyelitis: emerging insights across the age spectrum" [0.03%]
儿童和成人慢性非细菌性骨髓炎的最新研究进展
Aleksander Lenert,Polly J Ferguson
Aleksander Lenert
Purpose of review: To review and highlight key research findings in children and adults with chronic nonbacterial osteomyelitis (CNO). Recent findings: ...
Difficult-to-treat, complex-to-manage, treatment-refractory spondyloarthritis: semantics or substance? [0.03%]
难治、复杂和对治疗无反应的脊柱关节炎:仅仅是语义问题还是确有实质内容?
Olivier Fakih,Stephanie Rose Harrison,Helena Marzo-Ortega
Olivier Fakih
Purpose of review: The concept of difficult-to-treat (D2T) disease is increasingly recognized across immune-mediated inflammatory diseases, and was recently introduced in spondyloarthritis (SpA). Several terms, including ...
Update on IgA nephropathy: implications for treatment in IgA vasculitis: a guide for rheumatologists [0.03%]
IgA肾病的最新研究进展:对IgA血管炎治疗的意义——风湿科医师指南
Julia A Ford,Ora Gewurz-Singer
Julia A Ford
Purpose of review: IgA vasculitis (IgAV) and IgA nephropathy (IgAN) have historically been treated as distinct disease entities in clinical practice and in drug development, despite growing evidence speaking to a shared p...
Polyarticular juvenile idiopathic arthritis: insights from genetic studies on disease risk and pathogenesis [0.03%]
多关节型幼年特发性关节炎:遗传学研究揭示疾病风险和发病机制的新见解
Yuko Okamoto,Mayuko Fujisaki,Takako Miyamae
Yuko Okamoto
Purpose of review: Genetic and multiomics studies are reshaping our understanding of polyarticular juvenile idiopathic arthritis (JIA) and shifting the field from symptom- and phenotype-based categories toward biologicall...
Immune dysregulation in children with Down syndrome: clinical implications and emerging therapies [0.03%]
唐氏综合征儿童的免疫调节异常:临床意义和新兴疗法
Jessica L Bloom,Indira Sriram
Jessica L Bloom
Purpose of review: People with Down syndrome experience significant immune dysregulation, conferring elevated risk of autoimmune and inflammatory conditions. Despite the growing prevalence of adults living with Down syndr...
Choosing NSAID treatment in axial spondyloarthritis: factors guiding clinical decision-making [0.03%]
轴型脊柱关节炎非甾体抗炎药治疗的选择:临床决策的指导因素
Lianne S Gensler,Cailean E McKay,Adam S Mayer
Lianne S Gensler
Purpose of review: Nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line therapy for axial spondyloarthritis (axSpA), improving pain, function, and disease activity. This review evaluates evidence for NSAID efficac...