Mapping functional associations in the entire genome of Drosophila melanogaster using fusion analysis [0.03%]
利用融合分析绘制整个果蝇基因组的功能关联图
Ioannis Iliopoulos,Anton J Enright,Patrick Poullet et al.
Ioannis Iliopoulos et al.
We have previously shown that the detection of gene fusion events can contribute towards the elucidation of functional associations of proteins within entire genomes. Here we have analysed the entire genome of Drosophila melanogaster using ...
Beenome soon: honey bees as a model 'non-model' system for comparative genomics [0.03%]
比恩组学时代即将到来：利用蜜蜂作为比较基因组研究的非经典模式生物模型系统
Jay D Evans,Daniel B Weaver
Jay D Evans
Subbaya Subramanian,Vamsi M Madgula,Ranjan George et al.
Subbaya Subramanian et al.
Simple sequence repeats are predominantly found in most organisms. They play a major role in studies of genetic diversity, and are useful as diagnostic markers for many diseases. The simple sequence repeats database (SSRD) for the human gen...
Methylation analysis of several tumour suppressor genes shows a low frequency of methylation of CDKN2A and RARB in uveal melanomas [0.03%]
几种肿瘤抑制基因的甲基化分析表明CDKN2A和RARB在葡萄膜黑色素瘤中的甲基化频率较低
Michael Zeschnigk,Frank Tschentscher,Christina Lich et al.
Michael Zeschnigk et al.
We have investigated the frequency of methylation of several tumour suppressor genes in uveal melanoma. As the loss of one copy of chromosome 3 (monosomy 3), which is found in about half of these tumours, is tightly associated with metastat...
Reproducibility assessment of independent component analysis of expression ratios from DNA microarrays [0.03%]
基因表达比例的独立成分分析的重现性评估（DNA微阵列）
David Philip Kreil,David J C MacKay
David Philip Kreil
DNA microarrays allow the measurement of transcript abundances for thousands of genes in parallel. Most commonly, a particular sample of interest is studied next to a neutral control, examining relative changes (ratios). Independent compone...
Liaofu Luo,Hong Li,Lirong Zhang
Liaofu Luo
Some rules on gene recognition and ORF organization in the Saccharomyces cerevisiae genome are demonstrated by statistical analyses of sequence data. This study includes: (a) The random frame rule-that the six reading frames W1, W2, W3, C1,...
Jason Hinds,Kenneth G Laing,Joseph A Mangan et al.
Jason Hinds et al.
Adam A Witney,Jason Hinds
Adam A Witney
The manufacture and use of a whole-genome microarray is a complex process and it is essential that all data surrounding the process is stored, is accessible and can be easily associated with the data generated following hybridization and sc...
Lorenz Wernisch
Lorenz Wernisch
Microarray experiments are multi-step processes. At each step-the growth of cultures, extraction of mRNA, reverse transcription, labelling, hybridization, scanning, and image analysis-variation and error cannot be completely avoided. Estima...