Comparison of Alemtuzumab Versus Basiliximab Induction Therapy in Elderly Kidney Transplant Recipients: A Single-Center Experience [0.03%]
阿伦单抗与巴利昔单抗诱导治疗老年肾移植受者的比较：一项单中心体验
Idris Yakubu,Bharath Ravichandran,Tracy Sparkes et al.
Idris Yakubu et al.
Background: The optimal choice of induction immunosuppression for elderly kidney transplant recipients remains unclear. Although alemtuzumab has been associated with escalating risk of death and graft loss in this populat...
Evaluating Time to In-Hospital Venous Thromboembolism in Obese Patients [0.03%]
评估肥胖患者院内静脉血栓栓塞症的发病时间
B Tate Cutshall,Alexandra W Tatara,Navneet Upadhyay et al.
B Tate Cutshall et al.
Background: Currently, no consensus approach exists for optimal venous thromboembolism (VTE) prophylaxis in obese (BMI ≥30 kg/m2) patients. Time to development of in-hospital VTE is not well studied. ...
Joseph F Dasta,Sandra Kane-Gill
Joseph F Dasta
Acute kidney injury (AKI) develops in 8% to 16% of hospital admissions. These patients exhibit a 4- to 10-fold increase in mortality and prolonged hospital stays. There is a dearth of information on the economics of AKI, especially in criti...
Contemporary Topics in Critical Care With Evolving Medication Management Considerations [0.03%]
当今重症监护中的热点议题及不断发展的药物管理考虑因素
Sandra L Kane-Gill,Amy L Dzierba
Sandra L Kane-Gill
Clinical Pearls in Medical Toxicology: Updates Ranging From Decontamination to Elimination [0.03%]
中毒医学临牀诊疗要点：从现场处置到药物消除
Gabrielle L Procopio,Ruchi Patel,Amit Gupta
Gabrielle L Procopio
Such as any field of medicine, it is imperative to stay current with the latest advances and treatment modalities in toxicology. With the absence of rigorous randomized controlled trials, many updated guidelines are created by expert consen...
Impact of Dosing Conversion From Basal Insulin to Follow-On Insulin Glargine [0.03%]
从基础胰岛素转换为仿制甘精胰岛素的剂量换算的影响
Marina L Maes,Emily J Ashjian,Kellie A Kippes et al.
Marina L Maes et al.
Background: Several basal insulins have recently come to market including follow-on insulin glargine (Basaglar®). Currently, there is no real-world data published on the implications of conversion to Basaglar on dosing o...
Programmed Cell Death-1 Monoclonal Antibody Therapy and Type 1 Diabetes Mellitus: A Review of the Literature [0.03%]
程序性细胞死亡配体1单克隆抗体治疗与1型糖尿病：文献回顾
Kyle A Farina,Michael P Kane
Kyle A Farina
Two Food and Drug Administration-approved programmed cell death-1 (PD-1) inhibitors, nivolumab (Opdivo®), and pembrolizumab (Keytruda®), are indicated for treatment-resistant malignancies. Inhibition of PD-1 also inhibits T-cell periphera...
W Anthony Hawkins,Susan E Smith,Andrea Sikora Newsome et al.
W Anthony Hawkins et al.
Intravenous fluids (IVFs) are the most common drugs administered in the intensive care unit. Despite the ubiquitous use, IVFs are not benign and carry significant risks associated with under- or overadministration. Hypovolemia is associated...
Accuracy of Antiretroviral Prescribing in a Community Teaching Hospital: A Medication Use Evaluation [0.03%]
抗逆转录病毒处方准确性的社区教学医院评估：药物使用评估的一项研究
Jacob Lines,Paul Lewis
Jacob Lines
Background: Medication errors account for nearly 250 000 deaths in the United States annually, with approximately 60% of errors occurring during transitions of care. Previous studies demonstrated that almost 80% of partic...
Thomas Gregory,Leah Gregory
Thomas Gregory
Opioid misuse, abuse, and diversion continues to be a public health issue. Pharmacists (particularly those who work in the community setting) form the vanguard of health-care providers facing the opioid crisis because they have the opportun...