Oral Agents for the Treatment of Refractory Hypotension in the Acute Care Setting - A Narrative Review [0.03%]
急性期难治性低血压的口服治疗药物-综述
Gabrielle A Gibson,Annette D Lista,Jonathon D Pouliot
Gabrielle A Gibson
Refractory hypotension is a common occurrence in the acute care setting and is associated with a variety of conditions and underlying disease states. Persistent hypotension is associated with negative outcomes including organ failure and mo...
Tacrolimus in Solid Organ Transplantation: Historical Impact, Current Use, and Future Directions in Immunosuppression [0.03%]
他克莫司在实体器官移植中的历史影响、当前应用及未来免疫抑制方向
Rebecca Dieter,Ian S Jaffe,Aprajita Mattoo
Rebecca Dieter
Calcineurin inhibitors, particularly tacrolimus, have been a fundamental immunosuppressive treatment in solid organ transplantation for over four decades, helping prevent organ rejection in transplant recipients. Tacrolimus has also proven ...
Pharmacist Perspectives on High-Dose Methotrexate Management and Acute Kidney Injury Risk Mitigation in Patients With Lymphoma: Results From a National Survey [0.03%]
美国药师对淋巴瘤患者高剂量甲氨蝶呤管理及急性肾损伤风险防控观点的全国性调查结果
Elizabeth B King,Mikhaila L Rice,Huong L Truong et al.
Elizabeth B King et al.
Background: A summary of pharmacist-based practices and preferences regarding the prevention and management of high-dose methotrexate (HDMTX) toxicity in patients with lymphoma does not exist. The objective of the study was to describe curr...
Safety Outcomes of Tenecteplase Compared With Alteplase in Acute Ischemic Stroke: A Multicenter Retrospective Real-World Study [0.03%]
替奈普酶与阿替普酶治疗急性缺血性卒中的安全性结局：一项多中心回顾性真实世界研究
Hannah Walker,Sarah Tong,Nicole Horstman et al.
Hannah Walker et al.
Acute ischemic stroke (AIS) affects over 795,000 individuals annually in the U.S. and remains a leading cause of death. Alteplase has long been the standard thrombolytic therapy for AIS, though tenecteplase has recently gained attention due...
Optimizing Antimicrobial Timing: The Impact of Real-Time Pharmacist Review of Blood Cultures [0.03%]
抗菌药物给药时间的优化：药师实时审查血培养的影响
Ka Po Leung,Joanna DeAngelis,Nardine Karam Salgado et al.
Ka Po Leung et al.
Bacteremia is a potentially life-threatening infection, especially if sepsis or septic shock develops. The 2021 Surviving Sepsis Campaign recommends initiating antibiotics within the first hour for septic shock to improve patient outcomes. ...
Comparing Telepharmacy to Conventional Pharmacy Care: An Economic Evaluation [0.03%]
远程药房和传统药房照护的经济评估比较研究
Sophia Tam,Vishwanauth Persaud,Albert Wertheimer
Sophia Tam
Telehealth has become a mainstream healthcare delivery methods driven by advances in health technology, evolving patient preferences, and the need for more accessible and affordable care. While traditional pharmacy models remain effective, ...
Presentation of Acute Pancreatitis After Initiation of Phentermine/Topiramate for Weight Loss: An Adverse Drug Event Case Report [0.03%]
用于减肥的芬特明/托吡酯致急性胰腺炎案例报告
Michelle Balli
Michelle Balli
Background: Risk of acute pancreatitis is possible with several weight management medications including glucagon like peptide-1 receptor agonists. Acute pancreatitis has not been reported with the phentermine/topiramate combination product ...
Evaluation of Readability of Educational Materials for Coronary Artery Disease and the Impact of Health Literacy on Medication Adherence and Health Outcomes [0.03%]
冠心病教育材料的可读性评估及其对健康素养、用药依从性和健康结果的影响
Katelyn Gillies,Alexandra Bell,Caitlin McCarthy et al.
Katelyn Gillies et al.
Coronary artery disease (CAD) is a major problem in the United States, impacting 5% of American adults. Ensuring medication adherence is of vital importance, as lower adherence to cardiovascular medications is associated with higher risk of...
Physician Perspectives on Real-World Evidence for Prescribing to Older Patients [0.03%]
医师有关于老年人实际用药情况的证据的看法
Leah Z Rand,Junyi Wang,Steven Woloshin et al.
Leah Z Rand et al.
BackgroundAvailable evidence for many prescription drugs comes from clinical trials that often exclude older patients. Real-world evidence (RWE) generated post-approval can provide new evidence on effectiveness and safety for these populati...
Impact of Initial Heparin Rates on Reaching Goal Anti-Xa and Activated Partial Thromboplastin Time Within 48 Hours of Initiation in Patients With Mechanical Circulatory Support [0.03%]
初始肝素给药速度对植入机械循环支持装置患者于48小时内达到抗Xa和活化部分凝血活酶时间目标水平的影响
Jordan Orchard,Erica Caffarini,Angela Harding et al.
Jordan Orchard et al.
Background: Patients receiving mechanical circulatory support (MCS) devices should receive anticoagulation to avoid clotting of the circuit and to lower risk of acute thrombosis. Patients at our institution are initiated on UFH at 12 units/...