Comparison of Cefdinir and Cephalexin as Step-Down Therapy in Pyelonephritis or Urosepsis [0.03%]
cefadin与cephalexin用作肾盂肾炎或尿路脓毒血症序贯治疗的比较研究
Andrew R Miesner,Jonathan R Hurdelbrink,Sarah M Wall et al.
Andrew R Miesner et al.
Background: Cephalosporins are increasingly used to treat severe urinary tract infections (sUTI) due to rising resistance with standard antibioics. When switching from intravenous to oral cephalosporins there is limited clinical outcome dat...
Exploring the Link Between Intravenous Methocarbamol and Acute Kidney Injury [0.03%]
探究静脉注射甲氧卡巴胺与急性肾损伤之间的联系
Matthew Li,Avery Wilson,Phillip Dudley et al.
Matthew Li et al.
Background: Methocarbamol is a central nervous system depressant with antispasmodic properties used as a skeletal muscle relaxant as part of a multimodal analgesia regimen in critically ill patients. Intravenous (IV) methocarbamol contains ...
Aripiprazole-Induced Hyponatremia Observed Upon Rechallenge: A Case Report [0.03%]
阿立哌唑重新暴露诱发的低钠血症1例报告
Nicholas McGuire,Leslie Wu,Archana Jhawar
Nicholas McGuire
Medications account for nearly two-thirds of all cases of syndrome of inappropriate antidiuretic hormone secretion (SIADH). Numerous psychotropics including antipsychotics have been associated with SIADH but it is difficult to show a causal...
Comparison of Intravenous Regular Insulin Dosing Strategies in Adults With Acute Hyperkalemia [0.03%]
急性高钾血症成人患者静脉注射常规胰岛素剂量策略的比较研究
Michael OShea,Colleen Bond,Myroslava Sharabun et al.
Michael OShea et al.
Introduction: Intravenous (IV) regular insulin treats acute hyperkalemia. No guideline recommendations exist on the appropriate dose to be administered to maximize safety and efficacy. Objectives: The objective of this study was to evaluate...
End User Adaptation Experiences, Implementation Strategies, and Lessons Learned With the VIONE Medication Optimization and Safe Deprescribing Project in the Federal Health System [0.03%]
联邦卫生系统中VIONE药物优化和安全减药项目中的终端用户适应经验、实施策略及教训总结
Kimberly Dickerson,Shira Winter,Saraswathy Battar et al.
Kimberly Dickerson et al.
Purpose: There is extensive evidence linking Potentially Inappropriate Medication (PIM) use and adverse health outcomes. The VIONE core team and VA multidisciplinary partners created, implemented and disseminated the VIONE methodology acros...
Assessment of Midodrine Initiation and Vasopressor Liberation in Patients With Septic Shock in a Community-Teaching Hospital [0.03%]
社区教学医院中莫非多明起始与血管收缩剂撤机在脓毒性休克患者中的评估
Joel Kennedy,Alyssa Osmonson,Jessica A Starr et al.
Joel Kennedy et al.
Purpose: In observational trials, midodrine decreased vasopressor duration, length of stay (LOS), and mortality but not in randomized controlled trials. The goal of this study is to assess the efficacy and safety of using midodrine to wean ...
Efficacy of Intravenous Buprenorphine for Acute Pain in Critically Ill Patients in a Medical Intensive Care Unit [0.03%]
布托菲诺静脉给药对内科重症监护病房急性疼痛的疗效研究
Kennedi Satterfield,Jessica L Elefritz,Kyle Quirk et al.
Kennedi Satterfield et al.
Background: Buprenorphine is an opioid that has recently gained interest for acute pain management in post-operative patients. It has theoretical advantages due to its unique mechanism and favorable adverse effect profile...
Evaluation of Bleeding and Thrombotic Outcomes of Anticoagulation Strategies Upon Intensive Care Unit Admission for Patients with Atrial Fibrillation on Direct Oral Anticoagulants [0.03%]
直接口服抗凝药患者的房颤患者入住重症监护病房的抗凝策略的出血和血栓结局评估
Priya J Patel,Mariah I Sigala,Corey V Dinunno et al.
Priya J Patel et al.
Background: Critically ill adults are more commonly being admitted to intensive care units (ICU) with a recent history of direct oral anticoagulant (DOAC) use. No consensus guidance exists on optimal anticoagulation strategies in critically...
Olmesartan-Induced Enteropathy: Case Reports and Insights From FDA Adverse Event Reporting System (FAERS) [0.03%]
奥美沙坦引起的肠病:病例报告及美国食品药品监督管理局不良事件报告系统(FAERS)的分析启示
Ilaria Mariani,Giulia Mosini,Stefania Cheli et al.
Ilaria Mariani et al.
Olmesartan, an angiotensin II receptor blocker (ARB) approved in 2002, is used to treat hypertension, either alone or with other antihypertensive drugs. It has been frequently associated with sprue-like enteropathy, while few cases of colit...
Evaluation of Change in Medication Regimen Complexity-ICU (MRC-ICU) Score Following Implementation of a Virtual Intensive Care Model in a Multisite, Rural Health-System [0.03%]
虚拟重症监护模式多点实施后农村医疗体系中ICU用药复杂性评分(MRC-ICU)变化的评估
David Mastro,Karen Williams,Joshua Campbell
David Mastro
Background: Telehealth in the ICU (Tele-ICU) may improve patient outcomes and optimize utilization of high acuity intensive care unit (ICU) beds. However, the relationship between tele-ICU and medication regimen complexity-ICU (MRC-ICU) sco...