Physician Perspectives on Real-World Evidence for Prescribing to Older Patients [0.03%]
医师有关于老年人实际用药情况的证据的看法
Leah Z Rand,Junyi Wang,Steven Woloshin et al.
Leah Z Rand et al.
BackgroundAvailable evidence for many prescription drugs comes from clinical trials that often exclude older patients. Real-world evidence (RWE) generated post-approval can provide new evidence on effectiveness and safety for these populati...
Impact of Initial Heparin Rates on Reaching Goal Anti-Xa and Activated Partial Thromboplastin Time Within 48 Hours of Initiation in Patients With Mechanical Circulatory Support [0.03%]
初始肝素给药速度对植入机械循环支持装置患者于48小时内达到抗Xa和活化部分凝血活酶时间目标水平的影响
Jordan Orchard,Erica Caffarini,Angela Harding et al.
Jordan Orchard et al.
Background: Patients receiving mechanical circulatory support (MCS) devices should receive anticoagulation to avoid clotting of the circuit and to lower risk of acute thrombosis. Patients at our institution are initiated on UFH at 12 units/...
Perioperative Bleeding Risk of Direct Oral Anticoagulants Versus Warfarin in Kidney Transplantation [0.03%]
肾脏移植术中直接口服抗凝药物与华法林的术后出血风险比较研究
Shana Katz,Luke Slotterback,Goni Katz-Greenberg et al.
Shana Katz et al.
Background: Direct oral anticoagulants (DOACs) are commonly used for the treatment/prevention of thromboembolism. Data supporting the best practices for anticoagulation management, specifically with DOACs, at the time of solid organ transpl...
Isopropyl Alcohol-Induced Peripheral Neuropathy After Transdermal Exposure: A Case Report [0.03%]
透皮接触所致异丙醇外周神经病变一例报告
Jack Shapiro,Thomas Cranmer,Emma Formaro et al.
Jack Shapiro et al.
Peripheral neuropathy is a common neurological condition with diverse etiologies, including metabolic, infectious, and toxic exposures. While isopropyl alcohol (IPA) toxicity is well-documented in ingestion cases, transdermal exposure leadi...
Retrospective, Single-Center Evaluation of Dose Tapering Strategies of Dexamethasone in Hospitalized Patients With Malignant Spinal Cord Compression [0.03%]
一项回顾性、单中心评估地塞米松减药方案在恶性脊髓压迫住院患者中应用的研究
Drew A Wells,Samuel C Greer,Kerri Jones et al.
Drew A Wells et al.
Background: Historical trials of adjunctive dexamethasone for management of neurologic symptoms in malignant spinal cord compression (MSCC) utilized high doses of dexamethasone for 3 days then tapered over an additional 12 days. There is li...
Case Report of an Uncommon Dermatologic Manifestation of Disseminated Stenotrophomonas Maltophilia Infection in a Patient With Aplastic Anemia [0.03%]
一例伴发骨髓Failure的散在产黄放线菌感染所致罕见皮肤病案报告
Mei Qin Dong,Brynna Crovetto,Tania Kupferman
Mei Qin Dong
We present a case of ecthyma gangrenosum caused by Stenotrophomonas maltophilia in an immunocompromised patient with aplastic anemia and on antithymocyte globulin therapy, cyclosporine, and methylprednisolone treatment. We also conducted a ...
Impact of Pharmacist Intervention on Utilization of SGLT2 Inhibitors in Patients With Heart Failure With an Ejection Fraction Greater than 40 [0.03%]
药师干预对射血分数保留的心力衰竭患者使用钠-葡萄糖协同转运蛋白-2抑制剂的影响
Leanne Bockstruck,Kathryn Krei,Danielle Bozzardi-Jerome et al.
Leanne Bockstruck et al.
Introduction: Heart failure is a leading cause of morbidity and mortality worldwide. Literature suggests that the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors can be beneficial to decrease hospitalizations and cardiac mortality ...
Risk Factors for the Development of Dexmedetomidine-Related Fevers in Critically-Ill Patients [0.03%]
右美托咪定所致重症患者发热的危险因素分析
Hyun A Jae,Karina Muzykovsky,Jose Orsini
Hyun A Jae
Background: The Society of Critical Care Medicine's 2025 update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption suggest the use of dexmedetomidine...
Sustained Virologic Response Following a Shortened Course of Direct-Acting Antiviral Therapy in an HIV/HCV Co-Infected Patient With Previous Treatment Experience: A Case Report [0.03%]
直接抗病毒疗法短期疗程后HIV/HCV共感染患者的持续病毒学应答：一例报告
Natasha Bhutani,Yoona Lee,Maria A Longo et al.
Natasha Bhutani et al.
We describe a 47-year-old treatment-experienced African-American man co-infected with human immunodeficiency virus (HIV) and chronic hepatitis C virus (HCV) who took sofosbuvir-velpatasvir-voxilaprevir (SOF/VEL/VOX) for approximately 4 week...
Novel Prescription Delivery Program Impact on Hemoglobin A1c in Diabetes Mellitus [0.03%]
新处方配送项目对糖尿病患者糖化血红蛋白水平的影响
Rebecca D Fisk,Ashlyn M Kiebach,Jacob R Johnson et al.
Rebecca D Fisk et al.
Background: While traditional mail-order pharmacies have overcome some barriers to adherence, there is minimal evidence to indicate whether a novel prescription delivery program (PDP) can impact clinical endpoints in common disease states. ...