Impact of Pharmacist Intervention on Inappropriate Continuations of Antipsychotics upon ICU Discharge [0.03%]
药师干预对ICU出院患者不适当继续使用抗精神病药物的影响
Lauren T Dickman,Kelsey Bauman,Christopher K Carter et al.
Lauren T Dickman et al.
Background: Transitions of care (TOC) are important to best practices as they are at times prone to medication errors. The intensive care unit (ICU) is an essential location needing effective TOC due to many reasons, but an important one be...
Risk Factors Associated With Acute Kidney Injury in Traumatic Brain Injury Patients Treated With Hypertonic Saline: A Retrospective Study [0.03%]
高渗盐水治疗的颅脑损伤患者急性肾损伤的相关危险因素：一项回顾性研究
Jessica Briscoe,Megan Van Berkel Patel,R Chace Hicks et al.
Jessica Briscoe et al.
Background: Hypertonic saline (HTS) is essential pharmacologic treatment for traumatic brain injury (TBI). Previous studies associate HTS with acute kidney injury (AKI), however evidence in TBIs is limited. Objective: This study examines fa...
Prescription for Digital Evolution: Transformative Recommendations for Pharmacy Practice in the Digital Age [0.03%]
数字化时代的药学实践转型建议处方
Ayomide Ogundipe,Tin Fei Sim,Lynne Emmerton
Ayomide Ogundipe
Increased administrative tasks, evolving expectations of care and advancement in practice scope have rapidly advanced digital health. Health policy has acknowledged the need for evaluation to determine the technological needs of clinicians,...
The Effect of a Single-Dose Aminoglycoside With a Beta-Lactam for the Treatment of Gram-Negative Bacteremia [0.03%]
单剂量氨基糖苷类与β-内酰胺类药物联合治疗革兰氏阴性菌血症的效果
John Cerenzio,Justin Andrade,Joanna DeAngelis et al.
John Cerenzio et al.
Introduction: Aminoglycosides possess activity against aerobic gram-negative organisms and are often used in combination with beta-lactam antibiotics. Previous studies evaluating combination therapy in gram-negative bacteremia have not show...
Effective Treatment of Methotrexate Induced Oral Mucositis With a Morphine Mouthwash Solution: A Case Report [0.03%]
利多卡因止痛含漱液治疗甲氨蝶呤所致口腔黏膜炎疗效观察
Raha Hosseini,Shelby P Brooks,Elissa Gadelha et al.
Raha Hosseini et al.
Introduction: Methotrexate (MTX) is a common medication used to treat rheumatoid arthritis (RA). MTX inhibits rapid cell turnover throughout the body which can lead to significant side effects. Patients who present with oral lesions may hav...
Bupropion in Comorbid Post-Traumatic Stress Disorder and Methamphetamine Use Disorder [0.03%]
联苯环己烯联合治疗共病创伤后应激障碍和甲基安非他命使用障碍
Jamie Kneebusch,Sanaz Farhadian
Jamie Kneebusch
Background: Post-traumatic stress disorder (PTSD) and substance use disorder (SUD) frequently occur together. Serotonergic agents are preferred medications to treat PTSD, while bupropion is reserved due to limited evidence. Ongoing studies ...
Nationwide Survey to Characterize and Compare the Research Experiences of American Society of Health-System Pharmacists-Accredited Postgraduate Year One Pharmacy Residency Programs [0.03%]
关于美国卫生系统药学协会认可的 postgraduate year 1 岗位培训项目的研究经历的全国调查与比较
Andrea Dressler,Robert W Seabury,William Darko et al.
Andrea Dressler et al.
Background: Many Postgraduate Year One (PGY1) Pharmacy residencies provide research training however, details of this training are not well described. Publication rates have been utilized to assess residency research learning experiences. H...
Comparative Study
Journal of pharmacy practice. 2025 Feb;38(1):128-140. DOI:10.1177/08971900241273223 2025
Balanced Fluids Versus Normal Saline for Initial Fluid Resuscitation in Adults With Diabetic Ketoacidosis [0.03%]
糖尿病酮症酸中毒成人初始复苏使用平衡液与生理盐水的效果比较
Justin W Carter,Patrick M Whaley,G Christina Gutierrez et al.
Justin W Carter et al.
Background: Normal saline (NS) has been the choice fluid for volume resuscitation in diabetic ketoacidosis (DKA) for decades. Large volume resuscitation with NS can lead to hyperchloremic metabolic acidosis and is associated with a higher i...
Temporal Effect of CYP3A4/5 Induction on Ticagrelor's Pharmacodynamic Effects: A Case Series [0.03%]
CYP3A4/5诱导对替格瑞洛药理效应影响的时效性：病例系列报告
Thomas W Szymanski,Matthew R Rockhold,Jordan L Lacoste
Thomas W Szymanski
Ticagrelor is contraindicated in combination with cytochrome P450 3A4 and 3A5 enzyme (CYP3A4/5) inducers due to increased clearance, causing diminished antiplatelet effects. The emergent nature of acute coronary syndromes (ACS) may preclude...
A Case of Delayed and Persistent Carbamazepine Overdose Treated With Hemodialysis, Plasmapheresis, and Neostigmine [0.03%]
经久不愈的卡马西平中毒一例及其血透、血浆置换和新斯的明治疗效果
Kayla M Cameron-Coffill,Hari K Ondiveeran,Liam D Walsh
Kayla M Cameron-Coffill
Carbamazepine is utilized for various indications. Due to its pharmacokinetic profile and drug properties, toxicity can be delayed and persistent despite supportive care. We report a severe case of intentional carbamazepine toxicity in a ca...