Taylor Goostrey,Mitchell Ross,Karim Soliman et al.
Taylor Goostrey et al.
The most common formulation for treating ocular conditions is topical eyedrops, despite their well-documented inefficiency. In this study, mucoadhesive nano-micelles were developed to overcome the poor efficacy of topical eyedrops in the tr...
Development and utilization of a novel nanoantimicrobial suture for surgery: An in vivo and mechanical study [0.03%]
一种新型纳米抗菌缝合线的开发及应用：体内和机械性能研究
Yeliz Kılınç,İnci Rana Karaca,Aysel Uğur et al.
Yeliz Kılınç et al.
Development of surgical sutures coated with antimicrobial agents is a promising strategy to minimize surgical site infection (SSI) and improve wound healing. The antimicrobial features of Hypericum Perforatum and biogenic silver nanoparticl...
Multifunctional biopolymer-hydroxyapatite composite scaffolds for antibiotic delivery in osteomyelitis treatment and bone regeneration [0.03%]
用于骨髓炎治疗及骨组织再生的抗生素缓释型生物聚合物/羟基磷灰石复合支架研究
Tehseen Riaz,Anila Asif,Rabia Zeeshan et al.
Tehseen Riaz et al.
High bone-localized concentrations of antimicrobial agents are necessary for the long-term effective treatment of chronic osteomyelitis, particularly in cases of severe infection and bone loss. This study addressed infection control and bon...
Preclinical study on the application of biodegradable pure magnesium mesh in abdominal wall defect repair: Material characterization, biocompatibility, and regenerative mechanisms [0.03%]
可降解纯镁网修补腹壁缺损的前期研究：材料表征、生物相容性及再生机制探讨
Qi Zheng,Zequn Zhuang,Yonglin Li et al.
Qi Zheng et al.
This study evaluates a novel biodegradable magnesium (Mg) mesh for abdominal wall repair. Current synthetic meshes present clinical limitations, while Mg alloys offer favorable mechanical properties and biodegradability that remain underexp...
Dual-functional CuHP/Mg-CaP/PLLA nanofibrous scaffold for photothermal anti-infection therapy and enhanced bone regeneration [0.03%]
用于光热抗菌治疗和促进骨再生的双功能CuHP / Mg-CaP / PLLA纳米纤维支架
Jian Gu,Shuangjian He,Peng Zhang et al.
Jian Gu et al.
Infected bone defects are characterised by inadequate local blood supply and the formation of bacterial biofilms, which impede bone tissue regeneration and repair, presenting a significant clinical challenge. In this study, we developed a b...
Zinc doped silica nanoparticles gelatin methacrylate hydrogel on BMSCs cell viability and differentiation: Potential for rat mandibular bone defect repair [0.03%]
锌掺杂二氧化硅纳米颗粒明胶甲基丙烯酸酯水凝胶对BMSCs细胞存活和分化的影响：修复大鼠下颌骨缺损的潜能
Hai Liu,Yuteng Chen,Yifan Ma et al.
Hai Liu et al.
The various maxillofacial bone defect caused by fractures, tumors, and inflammationsis challenging to repair clinically. Therefore, developing a functional material with bone tissue regeneration capabilities has significant practical import...
pH-responsive dynamic organic nanocomposite hydrogels for enhanced local tumor combination therapy [0.03%]
用于增强局部肿瘤联合治疗的pH响应型动态有机纳米复合水凝胶疗法
Yang Yang,Hua Xie,Bi Zhou et al.
Yang Yang et al.
A single drug therapeutic approach fails to sufficiently eliminate tumors in clinics, owing to the tumoral complexity and heterogeneity. The integration of chemotherapy with novel treatment modalities offers a promising synergistic strategy...
Astragaloside II-loaded neutrophil nanocarrier drug delivery system for liver cancer treatment [0.03%]
载有 Astragaloside II 的中性粒细胞纳米递药系统用于肝癌治疗
Guangyi Gao,Xuan Jiang,Jun Ma et al.
Guangyi Gao et al.
Background: Liver cancer is one of the most lethal cancers globally, with current treatments offering limited efficacy and significant side effects. Astragaloside II (ASII), a compound derived from traditional Chinese medicine, shows promis...
Bioinspired 3D-printing strategies for skeletal tissue regeneration: From natural architectures to clinical applications [0.03%]
受生物启发的骨骼组织再生三维打印策略：从中尺度架构到临床应用
Sahar Jelodari,Payam Baei,Majid Halvaei et al.
Sahar Jelodari et al.
Skeletal tissues possess complicated structures and thereby their regeneration confronts considerable challenges. The final objective of skeletal tissue engineering is the development of efficient engineered substitutes in order to promote ...
Fabrication and in-vitro and in-vivo evaluation of polyacrylonitrile and polyethylene oxide nanofibers loaded with resveratrol and silver nanoparticles for skin wound healing application [0.03%]
负载白藜芦醇和银纳米粒子的聚丙烯腈及聚环氧乙烷纳米纤维的制备及其体内外评价用于皮肤伤口修复
Niloofar Seyedi,Somayeh Taymouri,Alireza Allafchian et al.
Niloofar Seyedi et al.
This study developed hybrid nanofiber scaffolds composed of polyacrylonitrile (PAN) and polyethylene oxide (PEO), loaded with resveratrol (RSV) and silver nanoparticles (Ag NPs), aiming to enhance wound healing and provide antimicrobial pro...