An injectable GelMA hydrogel improves Achilles tendon repair through local microenvironment modulation [0.03%]
通过局部微环境调节改善跟腱修复的可注射凝胶玛水凝胶
Mingyu Yang,Li Hu,Rui Chao et al.
Mingyu Yang et al.
Achilles tendon injury remains a major clinical challenge because of its limited intrinsic healing capacity and the high risk of disorganized extracellular matrix remodeling during repair. In this study, we developed an injectable gelatin m...
Promoting healing of Acinetobacter baumannii infected cutaneous wounds under hyperglycaemic condition via antibacterial and haemolytic Ag-Collagen/Al2O3/Cellulose nanodressings [0.03%]
一种抗菌和溶血性Ag-胶原/Al₂O₃/纤维素纳米敷料促进高糖条件下耐甲氧西林鲍曼不动杆菌感染的皮肤伤口愈合
Swati Sucharita Singh,Subhra Sourav Dash,Sankha Chakrabortty et al.
Swati Sucharita Singh et al.
Chronic diabetic wounds pose a persistent clinical problem due to ongoing infections and impaired lifestyle. Traditional silver-based therapies are often constrained by cytotoxicity and variable healing outcomes, underscoring the need for s...
Application of polydopamine coated silk fibroin methacryloyl hydrogel loaded with cell free fat extract in diabetic wound healing [0.03%]
聚多巴胺涂层蚕丝蛋白甲基丙烯酸酯水凝胶负载无细胞脂肪提取物在糖尿病伤口愈合中的应用
Qinhao Gu,Zexin Fu,Lu Wang et al.
Qinhao Gu et al.
Diabetic foot ulcers (DFUs) are common and serious problems in diabetes patients. They also represent one of the leading causes of non-traumatic lower limb amputation worldwide. Despite improvements in clinical care, numerous standard thera...
In vitro and in vivo evaluation of a bioactive polysaccharide based self-healing hydrogel film for enhanced wound healing [0.03%]
一种用于促进伤口愈合的生物活性多糖自修复水凝胶膜的体内外评价研究
Ayan Ranjan Hati,Chalamala Balagangadhar Reddy,Purnendu Ghosh et al.
Ayan Ranjan Hati et al.
The objective of this research was to develop a carboxymethyl chitosan (CMCS) loaded borax cross-linked guar gum (GG) self-healing hydrogel film dressing for enhanced wound healing. Cross-links between borax and GG were confirmed through FT...
Study on the homeostasis mechanism of in vivo degradation of PCL microsphere fillers [0.03%]
关于PLC微球植入体在体降解内环境稳定机制的研究
Shuang Wu,Qi Guo,Rongling Liu et al.
Shuang Wu et al.
Polycaprolactone (PCL) has been widely applied in the fields of medical aesthetics and clinical filling due to its excellent biocompatibility, controllable degradability, and favorable mechanical properties. However, the high crystallinity ...
Experimental study on the repair of rabbit femoral condyle critical-sized bone defect using polyphosphoester-amino acid copolymer-composite nanohydroxyapatite filling material [0.03%]
聚磷酸酯-氨基酸共聚物-纳米羟基磷灰石复合材料修复兔股骨髁大段骨缺损的实验研究
Mingzhong Xiao,Hua Gao,Hui Dong et al.
Mingzhong Xiao et al.
To engineer a porous nanohydroxyapatite/polyphosphoester-amino acid composite bone graft substitute (nHA/PPE-AA) in granular form and evaluate its reparative efficacy and in vivo safety in a rabbit femoral condyle critical-sized defect (CSD...
Effect of alloying and adding hydroxyapatite on the mechanical and corrosive properties of porous magnesium (Mg) [0.03%]
合金元素添加以及羟基磷灰石对多孔镁(Mg)力学及耐腐蚀性能的影响
Bisma Parveez,Nur Ayuni Jamal,Mohamad Ikhwan Bin Yusuff et al.
Bisma Parveez et al.
Porous magnesium (Mg) can be a promising material for biomedical application especially implants due to their low density, structure and properties comparable to human bones. In the current work, porous Mg composites were fabricated using p...
From leaf to cellulose scaffold: Decellularization and multi-scale characterization of Neolamarckia cadamba leaf for biomedical applications [0.03%]
从 Lamarckia cadamba 叶片到纤维素支架：用于生物医学应用的叶片去细胞化及多尺度表征
Sangeeta Devi Khangembam,Vipin Kumar Yadav,Anil Kumar Gangwar et al.
Sangeeta Devi Khangembam et al.
Exploring biological "orthogonality" between plant and animal kingdoms provides a unique opportunity to mimic biological features of both kingdoms. This novel approach can provide solutions to problems that animal kingdom faces. In this stu...
Gelatin-based cryogels seeded with exosomes enhance osteogenic activity and bone regeneration in a rabbit femoral defect model [0.03%]
明胶基冷冻水凝胶负载外泌体促进兔股骨缺损模型中的成骨活性及骨再生
Joseph Yang,Daniel Yang,Jhe-Lun Hu et al.
Joseph Yang et al.
The development of biomaterial scaffolds that combine structural support with biological activation remains critical for bone defect repair. In this study, gelatin-based cryogels (GBCs) that incorporate β-tricalcium phosphate (β-TCP) and ...
Carbon monoxide-releasing molecule-3 eradicates mature Enterococcus faecalis biofilms and inhibits recolonization [0.03%]
一氧化碳释放分子-3清除成熟的粪肠球菌生物被膜并抑制再定植
Jiahe Li,Xian He
Jiahe Li
Objective: To evaluate the effects of carbon monoxide-releasing molecule-3 (CORM-3) on Enterococcus faecalis biofilm inhibition and eradication, and assess its biosafety. Methods: CO release kinetics were measured by UV spectrophotometry. M...