Osteogenic differentiation by pre-osteoblasts is enhanced more on 3D-PRINTED poly-ɛ-caprolactone scaffolds coated with collagen and hydroxyapatite than on poly-ɛ-caprolactone/hydroxyapatite composite scaffolds coated with collagen [0.03%]
三维打印的聚乙交酯-ε-己内酯/羟基磷灰石支架上成骨细胞的成骨分化比聚乙交酯-ε-己内酯复合物/羟基磷灰石支架涂层更佳
Ali Moghaddaszadeh,Mohammad Ehsan Ghiasvand,Hadi Seddiqi et al.
Ali Moghaddaszadeh et al.
Three-dimensional (3D)-printed poly-ε-caprolactone (PCL) scaffolds lack sufficient bioactivity for optimal bone tissue engineering applications. This shortcoming can be overcome by coating PCL scaffolds with collagen and hydroxyapatite (PC...
Human blood preconditioned porcine arteries as potential conduits for human transplantation: Proof of concept in rabbit [0.03%]
人源化猪动脉移植的可行性研究：兔在体实验模型证明概念研究
Vijay Kumar Kuna,Bo Xu,Niclas Kvarnström et al.
Vijay Kumar Kuna et al.
Tissue-engineered arteries using natural scaffolds could overcome the drawbacks of autografts or artificial conduits used in the repair of many congenital cardiac defects and coronary artery bypass grafts. In this study, we present a novel ...
Multifunctional PEEK implants: Sulfonation-polydopamine synergy for bioactivity, wear resistance, and antibacterial efficacy [0.03%]
具有生物活性、耐磨性和抗菌性的多功能peek植入体：磺化-聚多巴胺协同作用
Qianqian Sun,Guangru Zhang,Guofa Zhang et al.
Qianqian Sun et al.
PEEK is a promising biomaterial for orthopedic and dental applications due to its excellent mechanical properties, biocompatibility, and bone-like elastic modulus. However, its bioinert surface limits osseointegration and predisposes it to ...
Synergistic enhancement of bone regeneration by obacunone-loaded peg-based composite scaffolds [0.03%]
载有Obacunone的PEG基复合支架协同促进骨再生
Xiuchen Yuan,Fengpin Yao,Dongfeng Li et al.
Xiuchen Yuan et al.
In this study, we report the design and fabrication of a novel biomimetic composite scaffold (PSGO) and systematically assess its potential for bone tissue engineering. The PSGO scaffold was fabricated using three-dimensional (3D) printing ...
Shifting the clinical paradigm: Copper versus silver wound dressings - Where we are and what we are looking for [0.03%]
临床范式的转变：铜与银创面敷料的选择——现状及未来展望
Ithamar Cheyne,Mateusz Rybka,Łukasz Mazurek et al.
Ithamar Cheyne et al.
The development of nanoparticle-based wound dressings marks a significant advancement in the management of chronic and non-healing wounds. Silver-based dressings have been used in wound management due to their strong antimicrobial propertie...
Development and evaluation of a ropivacaine-loaded hydrogel for prolonged nerve blockade and local anesthesia [0.03%]
一种用于长效神经阻滞和局部麻醉的罗哌卡因凝胶剂的开发与评估研究
Qunfei Zhang,Qihang Yang,Zhen Chen et al.
Qunfei Zhang et al.
This study explored the in vitro characteristics of a ropivacaine-loaded hydrogel designed for sustained local anesthesia, using a gelatin matrix crosslinked with different concentrations of NHS-PEG-NHS. The hydrogel was comprehensively cha...
The bioadhesive-thermoresponsive ophthalmic gel loaded solid dispersion of triamcinolone acetonide for improvement of ocular inflammation therapy [0.03%]
一种用于改善眼部炎症治疗的倍他米松磷酸钠载药固态凝胶眼用温敏凝胶
Hendra Stevani,Dwi Rachmawaty Daswi,Ratnasari Dewi et al.
Hendra Stevani et al.
Triamcinolone acetonide (TA) is a corticosteroid that has been widely used to treat ocular inflammation. However, due to the physicochemical properties of TA, this drug has low solubility and permeability. This study aims to improve the sol...
Ayana Kannaghut Puthukudi,Kaladhar Kamalasanan,Prajitha Prabhakaran Ganga et al.
Ayana Kannaghut Puthukudi et al.
Frequent insulin injections remain the primary method for regulating blood glucose levels in individuals with diabetes mellitus; however, patient compliance is often poor. Due to its non-invasive nature, oral insulin delivery, exploring nan...
Novel injectable tricalcium silicate composite bone cement with built-in antibacterial protection [0.03%]
一种具有内置抗菌保护的新型可注射三钙硅酸盐复合骨水泥
Azadeh Saberi,Amir Moeintaghavi,Hossein Bagheri et al.
Azadeh Saberi et al.
This investigation examines the influence of calcium sulfate (CaS) and modified nano-hydroxyapatite (mHA) additions on the physicochemical properties, microstructural development, apatite-forming potential, and antibacterial properties of b...
Altering the pH during sol-gel synthesis of bioactive glass particles and its effect on structural and antibacterial properties [0.03%]
pH值对生物活性玻璃溶胶凝胶合成的影响及其对结构和抗菌性能的影响
Danielle L Perry,Anthony W Wren
Danielle L Perry
In sol-gel glass chemistry, the pH of the sol directly influences the rate of the hydrolysis and condensation reactions, leading to changes in the glass's structural properties and potentially altering its function as a biomaterial. This re...