Anti-inflammatory and antioxidant effects of haematococcus carbon dots in ulcerative colitis: A nanoparticle-based approach [0.03%]
裂殖壶菌碳点在溃疡性结肠炎中的抗炎抗氧化作用:一种基于纳米粒子的方法
Yuting Liu,Mengqing Wang,Chaoyan Zhang
Yuting Liu
Ulcerative colitis (UC) is a chronic, non-specific inflammatory disease affecting the colon and rectum, classified as a type of inflammatory bowel disease (IBD). This study aimed to evaluate the therapeutic effects of Haematococcus carbon d...
Development of a ROS-responsive, glutathione-functionalized injectable hydrogel system for controlled drug release [0.03%]
一种ROS响应性、谷胱甘肽功能化可注射水凝胶控释载体系统的构建与发展
Kai Hu,Linlin Liang,Jian Song
Kai Hu
Oxidative stress arises from an imbalance between excessive production of reactive oxygen species (ROS) and the body's antioxidant defenses. In neurodegenerative diseases, this imbalance leads to ROS accumulation, causing neuronal dysfuncti...
A novel two-step conversion from DCPD-coated β-TCP to low crystallinity β-TCP porous scaffolds via combination between dry heating and hydrothermal methods: Effects on pre-osteoblast cell responses [0.03%]
一种新型两步法由DCPD包覆的β-TCP转化为低结晶度的β-TCP多孔支架:干热和水热结合的方法及其对成骨前细胞的作用
Ahmed Hafedh Mohammed Mohammed,Khairul Anuar Shariff,Mohamad Hafizi Abu Bakar et al.
Ahmed Hafedh Mohammed Mohammed et al.
This study presents a novel two-step process to fabricate low crystallinity (LC) β-tricalcium phosphate (β-TCP) porous scaffolds and evaluates their implications for pre-osteoblast cell responses. The novelty of this study lies in the two...
3D-printed nano-hydroxyapatite/poly(lactic-co-glycolic acid) scaffolds with adipose-derived mesenchymal stem cells enhance bone regeneration in rat model of bone defects [0.03%]
基于脂肪源性间充质干细胞的3D打印纳米羟基磷灰石/聚乳酸-こ谷氨酸乙縮醛多孔支架促进大鼠骨缺损修复中的成骨效应
Hai Yan,Fei Xia
Hai Yan
Three-dimensional (3D) printing has huge potential in the medical field, including bone tissue engineering scaffolds. In our study, the 3D-printed poly (lactic-co-glycolic acid) (PLGA)/nano-hydroxyapatite (HA) scaffolds carrying adipose-der...
Analysis of foreign body response and systemic toxicity of additively manufactured nanocellulose reinforced alginate gelatin-based scaffolds with interconnected 3D porous structure [0.03%]
三维多孔结构的纳米纤维素增强的藻酸盐明胶基支架的异物反应和系统毒性的分析
Sulob Roy Chowdhury,Bikramjit Basu
Sulob Roy Chowdhury
The last two decaes have witnessed significant efforts to develop gelatin/alginate based scaffolds using variants of 3D printing techniques. However, their biocompatibility for regenerating complex soft tissues remains insufficiently explor...
Selenium nanoparticles and paclitaxel co-delivery by a PCL based nanofibrous scaffold to enhance melanoma therapy [0.03%]
以PCL为基础的纳米纤维支架共传递硒纳米颗粒和紫杉醇以提高黑色素瘤治疗效果
Maryam Doostan,Ataollah Rahmani Azar,Hassan Maleki
Maryam Doostan
The incidence of skin cancer has increased significantly in recent decades, highlighting the need for more effective treatments due to the limitations of traditional approaches. This study focused on creating a poly (ε-caprolactone) and ch...
Silk fibroin-hyaluronic acid nanofibers for peripheral nerve regeneration [0.03%]
用于周围神经再生的丝纤维蛋白-透明质酸纳米纤维
Madeline R Badrak,Judy Senanayake,Ahmad Zunnu Rain et al.
Madeline R Badrak et al.
Peripheral nerve injuries are common and a major source of pain that can lead to debilitating loss of function. Current treatments are limited, with autologous nerve grafts being the gold standard treatment for nerve injuries. However, auto...
Enhancing Bone Regeneration with Silybin-Loaded PCL/Gelatin/Nanoclay Nanocomposite Scaffolds: An In Vitro & In Vivo Study [0.03%]
负载牛至的PCL/明胶/纳米粘土纳米复合支架促进骨再生的体内外研究
Mohammad Hossein Tayeed,Maryam Tehranchi,Arian Ehterami et al.
Mohammad Hossein Tayeed et al.
This study focuses on the development of a 3-dimensional porous scaffold using Polycaprolactone/Gelatin/Nanoclay (PCL/GNF/NC) for bone tissue engineering. The scaffold incorporates varying dosages of silybin (Sil) through a mixture of elect...
Preparation of SF-gel-CS-Hap bionic biphasic porous scaffolds and evaluation of physical, mechanical and biological properties [0.03%]
SF-gel-CS-Hap仿生双相多孔支架的制备及其理化、力学和生物性能评价
Mingxi Gu,Lin Guo,Changcheng Wang et al.
Mingxi Gu et al.
Objective: Full-thickness cartilage defect are usually accompanied by subchondral bone damage, which is difficult to self-repair once damaged due to the lack of vascularization and innervation. In this study, a biphasic composite scaffold w...
Porous oxidized dextran sponges for surgical hemostasis and infection control [0.03%]
用于外科止血和感染控制的多孔氧化葡聚糖海绵材料
Hong Xu,Siyuan Li,Peitao Zhuang
Hong Xu
Surgical procedures frequently result in varying degrees of bleeding and infection, which can impede patient recovery, particularly in situations of limited blood supply. Minimizing surgical blood loss and preventing infections remain cruci...