Letter to the Editor (Correspondence): Re: Prognostic Value of PARP1 and PARP2 Copy Number Alterations in Prostate Cancer [0.03%]
读者来信：关于前列腺癌中PARP1和PARP2拷贝数改变的预后价值
Laura Segalés,Silvia Hernández-Llodrà
Laura Segalés
General Pathologists Achieve Near-Specialist Diagnostic Performance Using Deep Learning-Based Virtual Staining for Donor Kidney Assessment: A Retrospecstive-Prospective Diagnostic Concordance Study [0.03%]
基于深度学习的虚拟染色技术使病理医师达到专科医生水平：回顾性-前瞻性诊断一致性研究——以供者肾脏评估为例
Jin-Peng Cen,Sheng-Dong Ge,Yang-Shu Zhou et al.
Jin-Peng Cen et al.
Conventional rapid evaluation of donor kidney quality primarily relies on hematoxylin and eosin (H&E) staining, which inadequately visualizes collagen fibers, compromising the assessment of interstitial fibrosis and posing challenges for ge...
Optimal Formalin-Fixed Paraffin Embedded Sample Preservation for Efficient Staining in Multiplex Imaging [0.03%]
适用于多重成像高效染色的优化福尔马林固定石蜡包埋样本保存方法
Yuna Delarue,Nadège Marec,Marion Le Rochais et al.
Yuna Delarue et al.
The accuracy of immunohistochemical techniques depends critically on the preservation of antigenic integrity in tissue samples. Although formalin-fixed paraffin-embedded tissues are commonly used for long-term storage, several studies repor...
Clonal Progression of a DNA Polymerase Epsilon-Mutant Endometrial Cancer With Immune Evasion Characteristics and Metastasis [0.03%]
带有免疫逃逸特性并发生转移的DNA聚合酶Epsilon突变型子宫内膜癌的克隆演化
Ruirui Fan,Jie Gao
Ruirui Fan
Renal transplant recipients are at significantly higher risk of developing malignancies due to chronic immunosuppression. While DNA polymerase epsilon (POLE)-mutated endometrioid carcinoma (EC) typically presents as early-stage disease with...
Highly Repeatable Tissue Proteomics for Kidney Transplant Pathology: Technical and Biological Validation of Protein Analysis using LC-MS/MS [0.03%]
用于肾脏移植病理学的高度可重复性组织蛋白质组分析：使用LC-MS/MS进行蛋白分析的技术和生物学验证
Rianne Hofstraat-Boersma,Kristina Marx,Renata Blatnik et al.
Rianne Hofstraat-Boersma et al.
Accurate pathological assessment of tissue samples is key for diagnosis and optimal treatment decisions. Traditional pathology techniques suffer from subjectivity resulting in inter-observer variability, and limitations in identifying subtl...
Differential Expression of PIWI-interacting RNAs in Glioblastoma Stem Cells Affects Their Biological Features: Implications for Tumor Progression and Patient Survival [0.03%]
PIWI相互作用RNA在胶质母细胞瘤干细胞中的差异表达及其对肿瘤进展和患者预后的影响研究
Frantisek Siegl,Elena Garcia-Borja,Rosana Mateu et al.
Frantisek Siegl et al.
Glioblastoma IDH-wild type (GBM) is the most lethal and, concurrently, the most common malignant primary brain tumor. Its aggressive behavior is associated with the presence of a subpopulation of glioblastoma stem cells (GSC) that drive res...
Erratum to "Establishing and characterizing the molecular profiles, cellular features, and clinical utility of a patient-derived xenograft model using benign prostatic tissues" (Lab Invest 2024 Oct;104(10):102129) [0.03%]
关于“利用良性前列腺组织建立和表征患者来源异种移植模型的分子谱型、细胞特征和临床应用”的勘误（实验室研究 2024年10月；104(10):102129）
Alexandra Lapat Polasko,Dalin Zhang,Avanti Ramraj et al.
Alexandra Lapat Polasko et al.
The Value of Internal Positive Controls and Synthetic Calibrators for Performance Assessment of Breast Carcinoma Estrogen Receptor Immunohistochemistry Assay [0.03%]
内部阳性对照和合成校准品在乳腺癌雌激素受体免疫组化检测性能评估中的价值分析
Emina E Torlakovic,Seshi R Sompuram,Søren Nielsen et al.
Emina E Torlakovic et al.
In 2010, the American Society of Clinical Oncology (ASCO) and the College of American Pathologists (CAP) jointly issued guidelines for estrogen receptor (ER) and progesterone receptor (PgR) testing and an update in 2020. Both guidelines rec...
Diagnostic Potential of Tn-MUC1 in Breast Cancer: A Novel Immunohistochemical Marker Reflecting Tumor Progression [0.03%]
Tn-MUC1在乳腺癌诊断中的潜力：一种反映肿瘤进展的新免疫组化标志物
Ai Shimizu,Kanako C Hatanaka,Ayae Nange et al.
Ai Shimizu et al.
Mucin 1 (MUC1) is a highly O-glycosylated transmembrane glycoprotein. Tumor-associated (TA) MUC1 (TA-MUC1), characterized by aberrant O-linked glycans, is overexpressed in cancer cells; however, conventional MUC1 antibodies show limited spe...
Identification of Potential FSGS through Evaluation of Parietal Epithelial Cells Status Changes Using Integrin α3 Immunostaining [0.03%]
利用整合素α3免疫染色评估足细胞状态变化鉴定潜在FSGS
Hui You,Kuo Wang,Mingshu Zhang et al.
Hui You et al.
Diagnosing primary focal segmental glomerulosclerosis (FSGS) remains challenging due to the lack of reliable biomarkers. This study investigates Integrin α3 as a diagnostic biomarker to differentiate FSGS from minimal change disease (MCD) ...