Myxoid pleomorphic liposarcoma-a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma [0.03%]
黏液性多形性脂肪肉瘤的临床病理、免疫组化、分子遗传和表观遗传学研究(12例报告)并提出与普通多形性脂肪肉瘤的关系探讨
David Creytens,Andrew L Folpe,Christian Koelsche et al.
David Creytens et al.
Myxoid pleomorphic liposarcoma is a recently defined subtype of liposarcoma, which preferentially involves the mediastinum of young patients and shows mixed histological features of conventional myxoid liposarcoma and pleomorphic liposarcom...
Breast implant-associated anaplastic large cell lymphoma: clinical follow-up and analysis of sequential pathologic specimens of untreated patients shows persistent or progressive disease [0.03%]
乳腺植入相关的间变性大细胞淋巴瘤：临床随访及未治疗患者的连续病理标本分析显示疾病持续或进展
Mark G Evans,L Jeffrey Medeiros,Mario L Marques-Piubelli et al.
Mark G Evans et al.
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a distinctive type of T-cell lymphoma that arises around textured-surface breast implants. In a subset of patients, this disease can involve surrounding tissues, spread to r...
The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma [0.03%]
去分化和转分化的黑色素瘤的临床病理学特征及基因组景观
Ingrid Ferreira,Alastair Droop,Olivia Edwards et al.
Ingrid Ferreira et al.
Dedifferentiation and transdifferentiation are rare and only poorly understood phenomena in cutaneous melanoma. To study this disease more comprehensively we have retrieved 11 primary cutaneous melanomas from our pathology archives showing ...
Clinicopathologic and prognostic features of TdT-negative pediatric B-lymphoblastic leukemia [0.03%]
TdT阴性儿童B淋巴细胞急性白血病的临床病理和预后特征
Matthew M Klairmont,Yinmei Zhou,Cheng Cheng et al.
Matthew M Klairmont et al.
Little is known about B-lymphoblastic leukemia (B-ALL) that lacks expression of terminal deoxynucleotidyl transferase (TdT). To address this, we performed the largest study to date of TdT-negative B-ALL using data from St. Jude Total XV and...
Diagnostic utility of one-stop fusion gene panel to detect TFE3/TFEB gene rearrangement and amplification in renal cell carcinomas [0.03%]
一站式融合基因检测在肾细胞癌中诊断TFE3/TFEB基因重排及扩增的临床应用价值
Shuko Harada,Anna Caliò,Karen M Janowski et al.
Shuko Harada et al.
MiT family translocation renal cell carcinoma (MiT-RCC) harbors translocations involving the TFE3 or TFEB genes. RCC with TFEB amplification is also identified and is associated with a more aggressive clinical course. Accurate diagnosis of ...
Loss of expression of YAP1 C-terminus as an ancillary marker for epithelioid hemangioendothelioma variant with YAP1-TFE3 fusion and other YAP1-related vascular neoplasms [0.03%]
YAP1-TFE3融合和其它YAP1相关血管肿瘤型 epithelioid hemangioendothelioma失去YAP1 C-末端表达作为辅助标志物
William J Anderson,Christopher D M Fletcher,Jason L Hornick
William J Anderson
Epithelioid hemangioendothelioma (EHE) with YAP1-TFE3 fusion is a recently characterized distinctive variant of EHE that accounts for a small subset (
Expression patterns for Bcl-2, EMA, β-catenin, E-cadherin, PAX8, and MIB1 in thymomas [0.03%]
Bcl-2、EMA、β-catenin、E-钙黏着蛋白、PAX8和MIB1在胸腺瘤中的表达模式
David Suster,James A Miller,German Pihan et al.
David Suster et al.
The expression of immunohistochemical markers has been extensively investigated in thymomas to assist in the differential diagnosis. We have studied six select markers to determine their utility in the evaluation of these tumors. A series o...
The sentinel node invasion level (SNIL) as a prognostic parameter in melanoma [0.03%]
Sentinel淋巴结侵袭程度（SNIL）作为黑色素瘤预后参数的影响
Lutz Kretschmer,Christina Mitteldorf,Simin Hellriegel et al.
Lutz Kretschmer et al.
Sentinel lymph node (SN) tumor burden is becoming increasingly important and is likely to be included in future N classifications in melanoma. Our aim was to investigate the prognostic significance of melanoma infiltration of various anatom...
Uterine PEComas: correlation between melanocytic marker expression and TSC alterations/TFE3 fusions [0.03%]
子宫PECom瘤中色素细胞标志物表达与TSC改变/TFE3融合的相关性研究
Jennifer A Bennett,Zehra Ordulu,Andre Pinto et al.
Jennifer A Bennett et al.
Uterine PEComas often present a diagnostic challenge as they share morphological and immunohistochemical features with smooth muscle tumors. Herein we evaluated a series of 19 uterine PEComas to compare the degree of melanocytic marker expr...
Mark Cameron Mochel,John B Wojcik,Madhu Gowda et al.
Mark Cameron Mochel et al.