Human papillomavirus infection is a favorable prognostic factor for patients with stage I-IVA esophageal squamous cell carcinoma but not adenocarcinoma [0.03%]
人乳头瘤病毒感染是Ⅰ-ⅣA期食管鳞癌患者预后的有利因素,但不是腺癌患者的有利因素
Celia Reynders,Diane Bruyere,Patrick Roncarati et al.
Celia Reynders et al.
With its two distinct histological subtypes [squamous cell carcinoma (SCC) and adenocarcinoma (ADC)], its rising incidence in both high- and low-income countries and its elevated 5-year mortality rate, esophageal cancer still represents a s...
Clinicopathologic and Molecular Analysis of Colorectal Carcinomas with Spectrum of Neuroendocrine Carcinoma Components [0.03%]
结直肠癌伴神经内分泌癌成分的临床病理和分子分析
Nazire E Albayrak,Bella L Liu,Meenakshi Mehrotra et al.
Nazire E Albayrak et al.
The genetics of colorectal carcinoma (CRC) with neuroendocrine differentiation remain poorly understood; recent studies focusing on pure neuroendocrine carcinomas (NECs) demonstrated mutation profiles closely resembling colorectal adenocarc...
Jintana Pankam,Nakarin Kitkumthorn,Siribang-On Piboonniyom Khovidhunkit et al.
Jintana Pankam et al.
Odontogenic myxoma (OM) is a rare benign mesenchymal odontogenic tumor. Presently, the molecular mechanisms underlying OM remain unclear, and no diagnostic markers have been identified. This study aimed to investigate gene mutations related...
MRI-Adapted Prostate Cancer Risk Tool Incorporating Cribriform and Intraductal Carcinoma [0.03%]
基于磁共振影像的前列腺癌风险预测模型及筛状和导管内癌的纳入价值
Ngoc-Nhu Jennifer Nguyen,Kristen Liu,Katherine Lajkosz et al.
Ngoc-Nhu Jennifer Nguyen et al.
Current prostate cancer risk stratification tools are not adapted for MRI-targeted biopsies and do not include the presence of cribriform/intraductal carcinoma (CC/IDC), an independent predictor of adverse clinical outcomes. We developed an...
Spatial evaluation and prognostic significance of VISTA in human resectable cervical carcinoma: Implications for immune activation and suppression [0.03%]
空间评价维斯塔在人类可切除性宫颈癌中的预后意义:免疫激活和抑制的启示
Qingshen Xie,Jinqing Li,Jieyao Li et al.
Qingshen Xie et al.
VISTA (V-domain Ig suppressor of T cell activation) is a promising next-generation immune checkpoint target. This study investigated the distribution and clinical significance of VISTA expression in cervical carcinoma. Using a cohort of 290...
Histological grade has clinical validity in neoadjuvant treated breast cancer: A multicenter study [0.03%]
新辅助治疗乳腺癌的组织学分级具有临床适用性:一项多中心研究
Sanna Steen,Constance Boissin,Mattias Rantalainen et al.
Sanna Steen et al.
The prognostic performance of histological grade in breast cancer is robust, but evidence for its clinical validity in the neoadjuvant setting is limited. Therefore, we evaluated grade in neoadjuvant treated breast cancer to investigate ass...
Feasibility of Histological Grading System of Small-sized Pulmonary Adenocarcinoma Based on Frozen Section as a Predictor for Nodal Metastasis [0.03%]
基于冰冻切片的微小肺腺癌组织学分级系统对淋巴结转移预测价值的可行性研究
Yukiko Sasahara,Satoshi Fumimoto,Seiyu Jeong-Yoo Ohtani-Kim et al.
Yukiko Sasahara et al.
Accurate prediction of lymph node metastasis is the key to selecting the best surgical approach for clinical stage N0 small-sized invasive pulmonary adenocarcinoma, especially when sublobar resection is considered. This study aimed to explo...
Erratum to "Beyond Hybrid Morphology: A Large Series of Fusion-Driven Benign Peripheral Nerve Sheath Tumors Including 5 Tumors With Novel Fusions" [Modern Pathology 38(2025) 100806] [0.03%]
“超越杂交形态:一组由融合驱动的良性外周神经鞘肿瘤的大系列,包括5种新型融合肿瘤”一文的勘误[现代病理学38(2025):100806]
Carina A Dehner,Tania Platero Portillo,George Jour et al.
Carina A Dehner et al.
Virtual histological staining as a tool for extending renal segmentation across stains∗ [0.03%]
虚拟组织学染色作为一种跨染色扩展肾段的工具
James Denholm,Azam Hamidinekoo,Nikolay Burlutskiy et al.
James Denholm et al.
In renal histopathology, the routine clinical use of several histological stains presents challenges for the direct application of stain-specific deep-learning-based analysis tools to whole-slide images. We present an approach to the in sil...
Analytical and Clinical Performance of the VENTANA CLDN18 (43-14A) RxDx Assay in Gastric and Gastroesophageal Junction Adenocarcinoma Tissue Samples in SPOTLIGHT and GLOW [0.03%]
VENTANA CLDN18(43-14A)伴随诊断试剂在SPOTLIGHT和GLOW研究中胃及胃食管交界处腺癌组织样本中的分析性能与临床性能
Steven P Stratton,Lizhen Pang,Judith Pugh et al.
Steven P Stratton et al.
New therapies are needed to treat patients with human epidermal growth factor receptor 2 (HER2)-negative, locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma. Zolbetuximab is a monoc...