Histology-Based Virtual RNA Inference Identifies Pathways Associated with Metastasis Risk in Colorectal Cancer [0.03%]
基于组织学的虚拟RNA推理识别结直肠癌转移风险相关途径
Gokul Srinivasan,Minh-Khang Le,Zarif Azher et al.
Gokul Srinivasan et al.
Colorectal cancer (CRC) remains a major health concern, with over 150,000 new diagnoses and more than 50,000 deaths annually in the United States, underscoring an urgent need for improved screening, prognostication, disease management, and ...
A Global Ring Study: Concordance Between Ventana PATHWAY anti-HER2/neu (4B5) Companion Diagnostic Assay and Comparators in Detecting HER2-low Breast Cancer [0.03%]
全球环形研究：Ventana PATHWAY anti-HER2/neu（4B5）伴随诊断试验与低表达HER2乳腺癌检测 comparator 方法的一致性分析
Hans-Ulrich Schildhaus,Sunil Badve,Corrado D&#x;Arrigo et al.
Hans-Ulrich Schildhaus et al.
Trastuzumab deruxtecan showed improved efficacy compared with treatment of physician's choice in human epidermal growth factor receptor 2 (HER2)-low (immunohistochemistry [IHC] 1+ or IHC 2+/in situ hybridization-negative) metastatic breast ...
Clinicopathologic and Genomic Characterization of SMARCA4-Deficient Carcinoma of the Gallbladder [0.03%]
SMARCA4缺陷型胆囊癌的临床病理和基因组特征分析
Qiqi Jia,Yishan Chen,Yuyao Pan et al.
Qiqi Jia et al.
As a key subunit of the SWI/SNF chromatin-remodeling complex, SMARCA4 plays a critical role as a tumor suppressor in various tumors. However, the clinicopathological and molecular features of SMARCA4-deficient carcinoma of the gallbladder (...
Recurrent BEND2 Fusion Genes Identified by Whole Transcriptome Sequencing of Non-Functional Pancreatic Neuroendocrine Tumors Correlate with Poor Patient Prognosis [0.03%]
全转录组测序鉴定的周期性BEND2融合基因与无功能性胰腺神经内分泌肿瘤患者的不良预后相关
Michelle A Wood-Trageser,C Tolson Nichols,Danielle A Hutchings et al.
Michelle A Wood-Trageser et al.
Pancreatic neuroendocrine tumors (PanNETs) exhibit heterogeneous clinical behavior, and a growing number of NF-PanNETs have been discovered incidentally. While chromatin remodeling and telomere maintenance gene alterations, such as ATRX and...
Genomic and transcriptomic landscape of Epstein-Barr virus-positive inflammatory follicular dendritic cell sarcoma: a multi-center study [0.03%]
多中心埃伯斯坦-巴病毒阳性炎性滤泡树突细胞肉瘤的基因组和转录组谱系特征研究
Yan Li,Ze-Lin Weng,Han-Xiao Fei et al.
Yan Li et al.
Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS) is a rare indolent malignant neoplasm, which occurs almost exclusively in the liver or spleen and may arise from a common EBV-infected mesenchymal...
Prognostic Significance of Desmoplastic Reaction Classification and Its Association with Stromal Biomarkers in Pancreatic Ductal Adenocarcinoma [0.03%]
胰腺导管腺癌间质反应分类的预后意义及其与间质生物标志物的关系
Shoko Noguchi,Takeo Yamamoto,Yoshiyuki Nakanishi et al.
Shoko Noguchi et al.
Pancreatic ductal adenocarcinoma (PDAC), an aggressive malignancy with a poor prognosis, is characterized by a dense desmoplastic stroma. Although preoperative treatments are increasingly utilized, the histological assessment of posttreatme...
Optical Genome Mapping in Myelodysplastic Syndromes: Clinical Value and Limitations Derived from a Cohort of 236 Patients [0.03%]
光学基因组学在骨髓增生异常综合征中的临床价值和局限性——来自236名患者的研究
Qing Wei,Sa A Wang,Guillermo Garcia-Manero et al.
Qing Wei et al.
Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution genome-...
Human Papillomavirus-Associated Penile Squamous Cell Carcinoma With Acquired p16 Null Immunophenotype [0.03%]
获得性p16阴性的与人乳头瘤病毒感染相关的阴茎鳞状细胞癌
Bryan E Luu,Stephanie E Siegmund
Bryan E Luu
Erratum to "Prediction of Response to Anti-HER2 Therapy Using A Multigene Assay" [Modern Pathology 38 (2025) 100713] [0.03%]
关于“使用多基因检测试验预测抗HER2治疗反应”一文的勘误(现代病理学 38 (2025) 100713)
Nehal Atallah,Shorouk Makhlouf,Xingmin Li et al.
Nehal Atallah et al.
Clinical and Prognostic Correlates of the Reticulin-Collagen-Osteosclerosis (RCO) Score in Primary Myelofibrosis [0.03%]
原发性骨髓纤维化中reticulin-collagen-osteosclerosis(RCO)评分的临床和预后相关因素分析
Raffaella Santi,Giacomo Coltro,Gioia Di Stefano et al.
Raffaella Santi et al.
Primary myelofibrosis (PMF) is hallmarked by stromal bone marrow changes, whose accurate evaluation holds diagnostic and prognostic implications. The reticulin (MF), collagen (Co), osteosclerosis (Ost) score (RCO-S) was developed in 2017 an...