A subset of serous tubal intraepithelial carcinoma (STIC)-like lesions and concurrent high-grade endometrial carcinoma are genomically related entities [0.03%]
一类浆液性输卵管上皮内癌（STIC）样病变和同时发生的高级别子宫内膜癌在基因组上具有相关性
Edaise M da Silva,Arnaud Da Cruz Paula,Kimberly Dessources et al.
Edaise M da Silva et al.
In patients with high-grade endometrial carcinoma (HG-EC), concurrent isolated serous tubal intraepithelial carcinoma (STIC) or STIC-like lesions (STIC-LLs) in the fallopian tube(s) may be found. We sought to determine whether concurrently ...
Comprehensive Molecular Profiling of Cribriform Tumors: Identification of Recurrent 6q/9q Codeletion and CD38 Expression [0.03%]
筛状肿瘤的综合分子特征分析：识别6q/9q共缺失和CD38表达
Pierre Sohier,Maxime Battistella,Maxime Mouthon et al.
Pierre Sohier et al.
Cribriform tumor is a distinctive cutaneous adnexal tumor with a cribriform growth pattern. Initially described as carcinomas, cribriform tumors exhibit an indolent clinical course. In contrast to many other adnexal skin neoplasms, the onco...
Ovarian Sex Cord Tumor with Annular Tubules (SCTAT) Harbor Recurrent Copy Number Alterations, Including Monosomy 22 [0.03%]
卵周性索-间质瘤伴管状结构的拷贝数变异特征包括22号单体染色体
Andrew M Leader,Alexander Neil,Stephanie Siegmund et al.
Andrew M Leader et al.
Sex cord tumor with annular tubules (SCTAT) is a rare ovarian sex cord-stromal neoplasm of low/intermediate malignant potential. While some SCTATs are associated with Peutz-Jeghers syndrome (PJS), the majority arise in the non-syndromic set...
Clinical, Morphologic, and Molecular Findings in NTRK3 Fusion Spitz Neoplasms [0.03%]
NTRK3融合Spitz肿瘤的临床、形态和分子特征
Afua Konadu Addo,Haya Mary Beydoun,Julia Edwin Jeyakumar et al.
Afua Konadu Addo et al.
NTRK3 fusions are a relatively common driver of Spitz neoplasms. This subset of Spitz neoplasms may have smaller cells without the typical abundant glassy eosinophilic cytoplasm seen in most Spitz neoplasms. This can make it difficult to re...
Nonhematopoietic malignancies in allograft kidneys: where does the tumorigenesis start? [0.03%]
异体肾脏移植后非造血系统恶性肿瘤的发病始基在哪里？
Melika Kooshki Forooshani,Fabiana Furci,Akanksha Sharma et al.
Melika Kooshki Forooshani et al.
Post-transplant malignancy is one of the major complications in patients who have received solid organ transplants. Malignant cells can be donor-transmitted, donor-derived or recipient-derived. We undertook a retrospective study on tumors a...
Antonios Papanicolau-Sengos,Omkar Singh,Kyung Park et al.
Antonios Papanicolau-Sengos et al.
Renal neoplasms are morphologically and molecularly heterogeneous with their diagnosis often hindered by inter-observer variability and overlapping microscopic features. A subset of cases are unclassifiable despite immunohistochemical, muta...
LYMPHOVASCULAR SPACE INVASION IN ENDOMETRIAL CANCER: DOES IT MATTER WHERE AND HOW MUCH TO SAMPLE? A MACROSCOPIC STUDY OF 208 HYSTERECTOMIES [0.03%]
子宫内膜癌的淋巴血管间隙侵犯：取材部位及数量是否影响其诊断的价值？208例子宫标本的大体观察
Deniz Ates,Aleyna Oruc,Sevilay Karahan et al.
Deniz Ates et al.
Lymphovascular space invasion (LVSI) is a key prognostic factor in endometrial cancer, guiding adjuvant treatment decisions. This retrospective study analyzed 208 hysterectomy specimens with confirmed LVSI to determine optimal sampling stra...
PolyPath: Adapting a Large Multimodal Model for Multi-slide Pathology Report Generation [0.03%]
PolyPath：适应大型多模态模型以生成多张病理报告
Faruk Ahmed,Lin Yang,Tiam Jaroensri et al.
Faruk Ahmed et al.
The interpretation of histopathology cases underlies many important diagnostic and treatment decisions in medicine. Notably, this process typically requires pathologists to integrate and summarize findings across multiple slides per case. E...
Deep learning-assisted system improves practical effect in cervical cytopathology diagnosis: A comparative study of reading modes [0.03%]
深度学习辅助系统可提升宫颈细胞病理诊断效率：一种阅读模式的比较研究
Zichen Ye,Peiyu Zhang,Ronggan Wei et al.
Zichen Ye et al.
Deep learning (DL) has significantly improved the diagnostic accuracy and efficiency of cytopathologists. However, current DL-assisted reading modes have yet to be fully evaluated, and there is limited evidence regarding cytopathologists' p...
Methylation Signatures Identify Two Distinct Clusters of Uterine Leiomyosarcoma with Unique Histologic and Clinical Behaviors [0.03%]
甲基化标志物识别子宫平滑肌肉瘤的两个独特的亚群及其对应的组织病理学和临床特征
Christopher Felicelli,Drew Duckett,Zachary Coty-Fattal et al.
Christopher Felicelli et al.
Uterine leiomyosarcoma (uLMS) is a rare and deadly gynecologic malignancy. uLMS is histologically heterogeneous and presents with a wide spectrum of tumor differentiation, with a broad range of genomic DNA instability, which can make the di...