Robert M van der Linde,David G P van IJzendoorn,Matt van de Rijn et al.
Robert M van der Linde et al.
Many benign and malignant bone and soft tissue tumors can contain giant cells, in variable amounts. In some tumors, such as tenosynovial giant cell tumor (TGCT) and giant cell tumor of bone (GCTB), these osteoclast-like giant cells are so p...
Comparative analysis reveals recurrent molecular alterations in low-risk HPV6 and HPV11-associated squamous cell carcinoma of the uterine cervix and vulva [0.03%]
比较分析发现低风险HPV6和HPV11相关宫颈和外阴鳞状细胞癌中的反复分子改变
Ying Sun,Colton Smith,Jason Murray et al.
Ying Sun et al.
While the association of HPV6 and HPV11 with squamous cell carcinomas (SCCs) has been well documented, the molecular alterations and mechanisms by which these low-risk HPVs contribute to carcinogenesis remain largely unknown. In this study,...
Clinicopathologic and Molecular Genetic Features of Spindle Cell Rhabdomyosarcoma harboring ZFP64::NCOA2/3 fusions: A Series of 14 Cases [0.03%]
一组14例含有ZFP64::NCOA2/3融合的梭形细胞横纹肌肉瘤的临床病理及分子遗传学特征
Carina A Dehner,Baptiste Ameline,Fernanda Amary et al.
Carina A Dehner et al.
Spindle cell rhabdomyosarcomas (SCRMS), recognized by the 2020 WHO Classification of Tumors of Soft Tissue and Bone as a distinct entity, comprise a family of malignant skeletal muscle tumors sharing spindle cell morphology. To date, member...
Deep Learning-Based Segmentation of Lung Adenocarcinoma Whole Slide Images for Objective Grading, STAS Identification, and Mutation Prediction [0.03%]
基于深度学习的肺腺癌全切片图像分割用于客观分级、STAS识别和突变预测
David Joon Ho,Jason C Chang,Rania G Aly et al.
David Joon Ho et al.
Manual quantification of morphologic patterns in lung adenocarcinoma is subject to reproducibility issues due to inter-pathologist variability. In this study, we developed a deep learning-based multi-class segmentation model providing a mod...
Head-to-head comparison of two artificial intelligence tools for detecting lymph-node metastases in whole slide pathology images within and beyond their intended use [0.03%]
两种人工智能工具在全片病理图像中检测淋巴结转移的头对头比较及其预期用途以外的应用评估
Rachel N Flach,Milan Samuels,Natalie D Ter Hoeve et al.
Rachel N Flach et al.
The increasing diagnostic workload in pathology, driven by rising cancer incidences, highlights the need for scalable, cost-effective solutions. Artificial intelligence (AI) has shown promise in supporting lymph node (LN) metastasis detecti...
Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions [0.03%]
皮肌炎样霉菌病，淋巴样乳头状皮炎Z和原发性皮肤间变性大细胞淋巴瘤的基因组分析发现了酪氨酸激酶基因融合的重复出现
Grant M Fischer,Harrison K Tsai,Jennifer Huang et al.
Grant M Fischer et al.
Pediatric cutaneous T-cell lymphoproliferative disorders encompass a diagnostically complex set of rare diseases of undefined pathogenesis, including mycosis fungoides (MF), lymphomatoid papulosis (LyP), and primary cutaneous anaplastic lar...
Corrigendum to "Magnetic Resonance Imaging (MRI)-Adapted Prostate Cancer Risk Tool Incorporating Cribriform and Intraductal Carcinoma" (Modern Pathology 2025 Dec;38(12):100852) [0.03%]
关于“适应磁共振成像（MRI）的前列腺癌风险工具，结合筛状和小叶癌”的更正（发表于《现代病理学》2025年12月第38卷第12期100852页）
Ngoc-Nhu Jennifer Nguyen,Kristen Liu,Katherine Lajkosz et al.
Ngoc-Nhu Jennifer Nguyen et al.
Corrigendum to "Spatial Evaluation and Prognostic Significance of V-Domain Immunoglobulin Suppressor of T-Cell Activation (VISTA) in Human Resectable Cervical Carcinoma: Implications for Immune Activation and Suppression" [Modern Pathology 2025;38(12):100851] [0.03%]
关于“人类可切除性宫颈癌中V域免疫球蛋白T细胞活化抑制剂(VISTA)的空间评估及预后意义：对免疫激活和抑制的启示”的勘误 [现代病理学 2025;38(12):100851]
Qingsheng Xie,Jinqing Li,Jieyao Li et al.
Qingsheng Xie et al.
Shaomin Hu,Daniela S Allende
Shaomin Hu
The diagnosis of liver metastases encompasses a broad-spectrum of entities and relies on clinicopathological correlation, with some cases be diagnosable using hematoxylin and eosin staining alone. For more challenging cases, ancillary testi...
Predicting the Probability of Residual Axillary Nodal Metastases in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy [0.03%]
新辅助化疗治疗乳腺癌患者腋窝淋巴结残存转移的预测模型
Thaer Khoury,Haiying Zhan,Xiao Huang et al.
Thaer Khoury et al.
In patients with breast cancer (BC) treated with neoadjuvant chemotherapy (NACT), a positive sentinel lymph node (SLN) usually requires completion axillary LN dissection (ALND). To enable de-escalation of this traumatic surgery, we aimed to...