Expanding the molecular characterization of adenoid ameloblastoma by assessing a panel of oncogenes and tumor suppressor genes [0.03%]
通过评估一组致癌基因和肿瘤抑制基因扩大腺样釉细胞瘤的分子特征研究
Ygor Gabriel Fonseca,Victor Coutinho Bastos,Rennan Garcias Moreira et al.
Ygor Gabriel Fonseca et al.
Adenoid ameloblastoma (AA) is a rare epithelial odontogenic tumor microscopically characterized by ameloblastoma-like epithelium, duct-like structures, epithelial whorls, cribriform architecture and dentinoid matrix. Wnt/β-catenin activati...
CD180 as a Robust Immunophenotypic Marker for Differentiating Lymphoplasmacytic Lymphoma/ Waldenström Macroglobulinemia from Marginal Zone Lymphoma [0.03%]
CD180作为区分淋巴浆细胞样淋巴瘤/沃登斯特罗姆巨球蛋白血症和边缘区淋巴瘤的稳健免疫表型标志物
Zhen Guo,Jing Su,Lu Liu et al.
Zhen Guo et al.
Precise differential diagnosis between lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM) and marginal zone lymphoma (MZL) remains a challenging issue because of overlapping clinicopathological and immunophenotypic features....
Perianal Intestinal-Type Paget's Disease With and Without Invasion, Unassociated With Internal Malignancy: A Distinct Form of Primary Perianal Adenocarcinoma [0.03%]
无内脏恶性肿瘤相关性的原发性肛周肠型Paget病伴有或不伴有侵袭性肿瘤的一种特殊形式
Dorukhan Bahceci,Carla Saoud,Raymond A Isidro et al.
Dorukhan Bahceci et al.
Primary perianal adenocarcinoma of intestinal type (PPAI) has been described in recent literature and proposed as a subtype of extramucosal anal adenocarcinoma. Whether this represents a unique entity remains to be elucidated. Herein, we an...
Expression of programmed death ligand-1 and programmed cell death-1 across the anal neoplasia disease continuum and association with survival in anal cancer [0.03%]
程序性死亡配体-1和程序性细胞死亡-1在肛管上皮内瘤变及肛癌中的表达及其与肛癌患者生存率的关系
Sona Chowdhury,Cynthia Gasper,Ann A Lazar et al.
Sona Chowdhury et al.
High-risk human papillomavirus (HPV) is associated with anal high-grade intraepithelial lesion (aHSIL) and anal squamous cell carcinoma (aSCC). The prognostic significance of PD-L1 expression in aSCC and its impact on overall survival (OS) ...
Cribriform tumor of the skin: identification of 6q and 9q loss as a recurrent cytogenomic alteration [0.03%]
皮肤筛状肿瘤的识别：作为细胞基因组改变复发性的6q和9q丢失
Shira Ronen,David G Grand,Wahab A Khan et al.
Shira Ronen et al.
Cribriform tumor is a rare sweat-gland neoplasm of uncertain malignant potential. Although its histopathologic features are well described, the molecular underpinnings of cribriform tumor remain incompletely characterized. We performed comp...
Methylation Profiles in Bone and Soft Tissue Tumors: Do They Help Classify the Unclassifiable? [0.03%]
骨和软组织肿瘤中的甲基化谱型：它们有助于分类无法鉴别的肿瘤吗？
Josephine Dermawan
Josephine Dermawan
Methylation profiling offers a promising avenue for improving the diagnosis and classification of bone and soft tissue tumors, particularly in cases where traditional methods fall short. Through examining tissue- and lineage-specific DNA me...
Tumors of the Synovium [0.03%]
滑膜肿瘤
Yee Lin Tang,Jad Husseini,G Petur Nielsen
Yee Lin Tang
The synovium is an integral component of synovial joints, as well as extraarticular structures such as the tenosynovium and bursae. This article reviews normal histology and the immunohistochemical profile of the synovium. It also discusses...
Unraveling Round Cell Sarcomas: A Contemporary Diagnostic Guide Beyond Ewing Sarcoma [0.03%]
解开圆形细胞肉瘤：超越尤因肉瘤的当代诊断指南
Raul Ezequiel Perret
Raul Ezequiel Perret
Round cell sarcomas represent a continuously evolving category of malignant mesenchymal tumors, currently encompassing five main tumor subtypes: Ewing sarcoma, CIC-rearranged sarcoma, sarcomas with BCOR-genetic abnormalities, PATZ1-rearrang...
Non-Neoplastic Orthopedic Pathology Updates: Common Problems and Pitfalls and How to Avoid Them [0.03%]
骨科非肿瘤病理更新：常见问题与陷阱及如何避免它们
Scott E Kilpatrick
Scott E Kilpatrick
Despite representing less than 1% of all musculoskeletal surgical pathology cases, primary musculoskeletal neoplasms are disproportionately emphasized in the surgical pathology literature, compared to non-neoplastic orthopedic pathology. Ye...
Replacing molecular testing with next-generation immunohistochemistry: I can diagnose that soft tissue tumor with a single antibody! [0.03%]
下一代免疫组化替代分子检测：我可以用单一抗体诊断软组织肿瘤！
Jason L Hornick
Jason L Hornick
Immunohistochemistry plays a central role in the diagnosis of soft tissue tumors. Conventional immunohistochemistry employs antibodies directed against lineage-restricted antigens, in an attempt to identify a line of differentiation and nar...