Analytical Comparison of Commonly Used Laboratory-Developed Tests for the Assessment of Ki-67 in Breast Carcinoma With an FDA-Approved Benchmark [0.03%]
与FDA批准的参考标准对比分析用于评估乳腺癌中Ki-67的常用实验室检查方法性能指标
Sunil Badve,Jason S White,Francisco Sapunar et al.
Sunil Badve et al.
Ki-67 immunohistochemistry (IHC), a commonly used assay for breast cancer risk prognostication, has significant inter-laboratory heterogeneity. This study assessed the impact of antibody clones by comparing the Ki-67 IHC MIB-1 pharmDx assay...
Immune Cellular Patterns Predicting Lymph Node Status Helps Personalized Management of Stage T1 Esophageal Squamous Cell Carcinoma [0.03%]
免疫细胞图谱预测淋巴结状态有助精准管理T1期食管鳞癌
Hangjia Zhu,Xiangli Fan,Chenghao Liu et al.
Hangjia Zhu et al.
Endoscopic resection preserves esophageal integrity in stage T1 esophageal squamous cell carcinoma (ESCC), but its inability to address regional lymph node metastasis (LNM) necessitates novel strategies for risk stratification. This study a...
Mark G Evans,Sara O Vargas,Adam Bedeir et al.
Mark G Evans et al.
Deciphering Pseudoendocrine Sarcoma: a clinicopathological, molecular and epigenetic study suggesting biological links with Solid Pseudopapillary Neoplasm of the Pancreas [0.03%]
伪内分泌肉瘤的破解：一项临床病理、分子和表观遗传学研究，提示其与胰腺实性假乳头状瘤具有生物学联系
Juan Fernández-Pérez,Isabelle Pommepuy,Michael Michal et al.
Juan Fernández-Pérez et al.
Pseudoendocrine sarcoma (PS) is a recently described neoplasm of uncertain differentiation, characterized by recurrent CTNNB1 mutations, frequent paravertebral location, and a neuroendocrine-like histomorphology. In this study, we report th...
Clinicopathologic Features of Untreated Colorectal Cancer with Acellular Mucin-Only Lymph Nodes [0.03%]
未治疗的结直肠癌伴仅有黏蛋白的无细胞淋巴结的临床病理特征
Wenyi Luo,Shaomin Hu,Irene Rana Riahi et al.
Wenyi Luo et al.
Lymph nodes (LNs) containing only acellular mucin are considered negative for metastasis in treated colorectal cancers (CRCs). However, no data exist on how to stage these LNs in untreated CRCs. We collected 63 untreated CRC cases with LNs ...
Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes: Authors' Response to "Concerns and Issues" [0.03%]
对“质疑与问题”的回应：关于骨髓增生异常肿瘤/综合征诊断和分类的现代观点
Fnu Aakash,Sanam Loghavi
Fnu Aakash
Prognostic value of an integrated human papillomavirus and immunoscore model to predict survival in vulva squamous cell carcinoma [0.03%]
整合人类乳头瘤病毒和免疫评分模型预测外阴鳞状细胞癌生存预后的价值
Rammah Elnour,Ingjerd Helstrup Hindenes,Malene Færevaag et al.
Rammah Elnour et al.
While the prognostic value of immune-related biomarkers is well characterized in many solid tumors, their significance in vulva squamous cell carcinoma (VSCC) remains unclear. Here, we report a comprehensive analysis of programmed death-lig...
Beyond Hybrid Morphology: A Large Series of Fusion-Driven Benign Peripheral Nerve Sheath Tumors Including 5 Tumors with Novel Fusions [0.03%]
超越杂交形态：一组由融合驱动的良性外周神经鞘肿瘤（包括5种新型融合肿瘤）
Carina A Dehner,Tania Platero-Portillo,George Jour et al.
Carina A Dehner et al.
Benign peripheral nerve sheath tumors (PNSTs) represent a heterogeneous group of neoplasms with varying histological and molecular characteristics. While traditional classifications categorize these tumors based on predominant cell types, r...
Phenotypic and molecular features of somatically-derived "yolk sac tumors": similarities and differences with counterparts of germ cell origin [0.03%]
源自体细胞的「卵黄囊肿瘤」的表型和分子特征与其生殖细胞来源的同源肿瘤的异同点分析
João Lobo,Nuno Tiago Tavares,Fernanda Fernandes-Pontes et al.
João Lobo et al.
A subset of somatic carcinomas shows morphologic and immunophenotypic similarities to yolk sac tumor (YST) of germ cell origin, including fetal adenocarcinomas of the lung (FLACs) and somatic carcinomas with "YST"/enteroblastic differentiat...
The spectrum of placental findings of first trimester cytomegalovirus infection related to the presence of symptoms in the newborns and stillbirths [0.03%]
早孕期巨细胞病毒感染相关的胎盘表现与新生儿及死产儿的症状有关性研究
Eva Manuela Pena-Burgos,Rita María Regojo-Zapata,Ángela Caballero-Ferrero et al.
Eva Manuela Pena-Burgos et al.
Cytomegalovirus (CMV) is one of the most common congenital infections worldwide and a leading cause of prenatal neurological disorders, sensorineural hearing loss, and stillbirth. The placental factors involved in CMV transmission from moth...