Parvalbumin 5 potentially regulates Fsh cells but not Lh cells in the pituitary of ricefield eels† [0.03%]
Parvalbumin 5可能调节稻田鳗垂体中的Fsh细胞但不能调节Lh细胞
Zhiguo Wang,Shuya Chen,Zhiyu Yang et al.
Zhiguo Wang et al.
Parvalbumins (Pvalb) are members of the EF-hand protein superfamily which have been shown to play important roles in the nervous system and muscle. In the present study, the expression and potential roles of parvalbumin 5 (Pvalb5), a member...
C-type natriuretic peptide pre-maturation culture affects cytoplasmic maturation in bovine oocytes† [0.03%]
C型利钠肽前成熟培养影响牛卵母细胞胞质成熟度
Emily Girka,Ashlyn Brewer,Hao Ming et al.
Emily Girka et al.
In vitro oocyte maturation (IVM) is a vital step for many assisted reproductive technologies including in vitro embryo production. Modulation of ribonucleic acid (RNA) transcripts, lipids, mitochondria, and other molecules during maturation...
Multi-omics analysis reveals steroid hormone biosynthesis as a key pathway in advanced maternal age threatened abortion [0.03%]
多组学分析揭示类固醇激素生物合成途径在高龄妊娠流产中的关键作用
Xia Liu,Tianjiao Liu,Xuemei Zou et al.
Xia Liu et al.
Background: Advanced maternal age (AMA, ≥35 years) is increasingly common and is accompanied by rising threatened abortion (AMA-TA) rates, yet its molecular basis remains unclear. ...
Retinoic acid rescues heat stress-induced estrous cycle disruption by enhancing Cyp19a1 expression through the Ca 2+-pSTAT3-H3K27me3 axis† [0.03%]
视黄酸通过Ca 2+-pSTAT3-H3K27me3轴增强Cyp19a1表达缓解热应激诱导的发情周期紊乱
Fupeng Wang,Qianhui Sun,Guo Sun et al.
Fupeng Wang et al.
Global warming poses a public health risk, and heat-induced reproductive defects are a growing concern for both humans and animals. Disrupted estrous cycle and reduced estrogen synthesis are notable changes in females exposed to heat stress...
Systems-level proteomic profiling reveals modular control of human cervical remodeling during pregnancy† [0.03%]
系统水平的蛋白质组学分析揭示了人类宫颈重塑在怀孕期间模块化控制的作用
Yuguo Deng,Zhiguang Zhao,Hanbo Liu et al.
Yuguo Deng et al.
Cervical remodeling (CR) is essential for pregnancy maintenance and successful parturition, yet its molecular regulation in humans remains incompletely defined. This study aimed to present a high-resolution, longitudinal proteomic atlas of ...
Diisobutyl phthalate alters estradiol synthesis and expression of genes associated with epigenetic regulation and inflammation in bovine granulosa cells [0.03%]
邻苯二甲酸二异丁酯通过表观遗传修饰和炎症相关基因表达，干扰牛颗粒细胞中雌二醇的合成
Camilo Andres Pena-Bello,Isadora Maria Batalha,Evandro Carlos Archilia et al.
Camilo Andres Pena-Bello et al.
Phthalates are widely used plasticizers that leach into the environment and have impacts on health and fertility of humans and animals. Among these ubiquitous environmental contaminants is diisobutyl phthalate (DiBP), a plasticizer known to...
KAT2A contributes to premature ovarian insufficiency by activating the P38/MAPK signaling pathway to drive granulosa cell dysfunction [0.03%]
KAT2A通过激活P38/MAPK信号通路促进颗粒细胞功能障碍从而参与卵巢早衰发生
Jia Li,Yiting Liu,Linfei Huang et al.
Jia Li et al.
Premature ovarian insufficiency (POI), a major cause of female infertility, is a condition where the ovaries lose their function before the age of 40. Growing evidence suggests that Lysine acetyltransferase 2A (KAT2A) has been identified as...
From Adhesion to Communication: How Sperm Binding Modulates the Bovine Oviductal Microenvironment† [0.03%]
从附着到交流：精子结合如何调节牛输卵管微环境
José de Oliveira Carvalho,Paula Renata Cortat,André Bianchini Covre et al.
José de Oliveira Carvalho et al.
Fertility in mammals is influenced by the interaction between spermatozoa and the female reproductive tract. While sperm has traditionally been regarded as passive carriers of paternal DNA, there is growing evidence that they actively influ...
A Vaginal Microbiota-Ovary Axis in Chemotherapy-Accelerated Ovarian Aging: Single-Cell Insights into Cellular Dysregulation [0.03%]
化疗加速卵巢衰老的阴道微生态-卵巢轴：单细胞视角下细胞失调的新认识
Shuxin Zhou,Xinfeng Bai,Binqing Xue et al.
Shuxin Zhou et al.
Background: Chemotherapy-induced premature ovarian failure (POF) represents a major challenge to female reproductive health, yet the potential regulatory role of vaginal microbiota in this process remains largely unexplor...