Differential expression of microRNAs after induction of endometriosis in baboons [0.03%]
恒河猴子宫内膜异位症诱导后的微小核糖核酸的差异表达
Ramanaiah Mamillapalli,Hanna Surmann,Niraj Joshi et al.
Ramanaiah Mamillapalli et al.
Endometriosis is an inflammatory chronic gynecological condition that affects 10-15% of reproductive-age women which causes pelvic pain and infertility. The disease is characterized by the growth of endometrial tissue outside the uterine ca...
Reduced Circulating Polyamines in Polyendocrine Metabolic Ovarian Syndrome (PMOS) Patients and the Impact of Putrescine on Ovarian Function and Fertility in a Murine PMOS Model [0.03%]
多内分泌代谢性卵巢综合征(PMOS)患者的循环多胺减少及尸胺对小鼠PMOS模型卵巢功能和生育力的影响
Subrata Das,Joseph R D Fernandes,P T Nikhil et al.
Subrata Das et al.
GnRH is essential for regulating the reproductive system in mammals. Recent research has shown that polyamines, biogenic amines produced in body, can regulate GnRH levels. These polyamine levels are affected by metabolic disorders like diab...
Sylvie Chastant
Sylvie Chastant
Developmental programming in dogs, although less studied than in other species, encompasses both nutritional and behavioural influences during gestation and early life. The most critical window corresponds to the first 120 days (pregnancy f...
Kei-Ichiro Ishiguro,Yasuhiro Fujiwara
Kei-Ichiro Ishiguro
Meiosis requires specialized mechanisms to coordinate chromosome pairing, recombination, and stepwise chromosome segregation. Central to these processes are cohesin complexes that incorporate meiosis-specific subunits, including SMC1β, REC...
Yunxuan Huang,Yaping Liang,Jing Chen
Yunxuan Huang
Lactate, once considered merely the product of glycolysis, is now recognized as both a metabolic fuel and a signaling molecule with broad physiological and pathological roles. The landmark discovery of lysine lactylation in 2019 unveiled a ...
Mitochondria as Integrative Regulators of Ferroptosis in the Female Reproductive System [0.03%]
线粒体在线粒体在女性生殖系统铁死亡中的整合调节作用
Isil Yenigun,Nazli Ece Huner,Aylin Yaba
Isil Yenigun
Mitochondrial function is fundamental to female reproductive physiology, supporting follicular development, oocyte maturation, and endometrial remodeling. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidat...
Navigation of Nanos germ cell specification factor to germ granules-posttranscriptional regulation hubs-across species† [0.03%]
跨物种的Nanos原肠胚细胞决定因子在原肠胚颗粒之间的导航及其对转录后调节中心的作用
Bellary Lakshmi,Matisa Alla,Jadwiga Jaruzelska
Bellary Lakshmi
NANOS, initially identified in Drosophila melanogaster (fruit fly) as a morphogen essential for body patterning and germ cell development, is a highly conserved ribonucleic acid (RNA)-binding protein critical for germ cell formation across ...
Spatiotemporal Dynamics of NK Cell Immune Checkpoints Tim-3 and Lag-3 in Human Pregnancy: An Integrated Peripheral and Decidual Compartment Analysis [0.03%]
人妊娠期间杀伤细胞免疫检查分子Tim-3和Lag-3的时空动态变化:外周血与蜕膜综合分析
Daojing Li,Xianhong Tong,Yanyan Yang et al.
Daojing Li et al.
Pregnancy represents a unique state of immune adaptation requiring precise regulation to maintain tolerance toward the semi-allogeneic fetus. Although natural killer (NK) cells and T cells play central roles in maternal-fetal immunity, gest...
Alex S Flynt,Neta Nnabuenyi,Cory Von Eiff et al.
Alex S Flynt et al.