Efficient generation of single copy transgenic mice using piggyBat transposase from the little brown bat Myotis lucifugus† [0.03%]
利用小棕蝠（Myotis lucifugus）的piggyBat转座酶高效生成转基因小鼠
Eiichi Okamura,Shoma Matsumoto,Hayate Suzuki et al.
Eiichi Okamura et al.
Transgenic animals are invaluable tools in genetic studies, disease modeling, drug discovery, and biotechnology. However, the low efficiency of transgenic animal generation can be an obstacle to their application. Here, we report the genera...
Equine Endometrial Organoids Preserve Tissue Structure and Cycle-Stage Transcriptional Identity† [0.03%]
马子宫内膜类器官保持组织结构和周期阶段转录身份
Margo Helene Verstraete,Fianne Kuijpers,William Holl et al.
Margo Helene Verstraete et al.
The endometrium is a hormonally responsive tissue that undergoes cyclic remodeling. Although endometrial organoids have been established in several species, detailed characterization remains limited. Here, we assessed the structural and mol...
Cardiovascular phenotype analysis in large and abnormal offspring calves in relation to assisted reproductive technology† [0.03%]
与辅助生殖技术有关的大型和畸形后代犊牛的心血管表型分析
Elizabeth Williams Louie,Amanda A Macias,Katharyn J Mitchell et al.
Elizabeth Williams Louie et al.
Intro- Large offspring syndrome/Abnormal Offspring syndrome (LOS/AOS) occurs at an increased frequency in calves derived from assisted reproductive techniques (ART). Specific criteria for LOS diagnosis in calves are lacking. Cardiac and vas...
AMH induces a reversible quiescence-associated secretory phenotype in preantral follicles† [0.03%]
抗缪勒管激素使窦前卵泡产生可逆性的静止相关分泌表型
Marie-Charlotte Meinsohn,Josephine Cleverdon,Alana M Mermin-Bunnell et al.
Marie-Charlotte Meinsohn et al.
Anti-Müllerian hormone (AMH) is a factor secreted by granulosa cells of growing follicles that regulates many aspects of ovarian function including primordial follicle activation and early follicle development through inhibitory feedback. ...
The Effects of House Dust-Derived Mixtures of Organophosphate Esters on Leydig Cell Phenotype, Function, and Lipidome [0.03%]
房屋尘土衍生的有机磷酯混合物对类固醇间质细胞表型、功能和脂质体的影响
Zixuan Li,Xiaotong Wang,Barbara F Hales et al.
Zixuan Li et al.
Organophosphate esters (OPEs), widely used as flame retardants and plasticizers, are frequently detected in indoor environments and human tissues, raising concerns about their potential endocrine-disrupting effects. In this study, we examin...
Laurie Francoeur,Deena M Scoville,Jaclyn G Ahern et al.
Laurie Francoeur et al.
Selective breeding in laying hens has resulted in a laying rate of approximately one egg per day during their first year. Due to variability within a flock, this rate declines after the first year, leading producers to cull hens. The aim of...
Uterine histotroph and conceptus development. V. Comparative analyses of arginine-mediated transcriptomic reprogramming in conceptus trophectoderm of pigs and sheep [0.03%]
子宫液和胎儿发育。V.猪和绵羊胚胎滋养层精氨酸介导的转录组重编程的比较分析
Sudikshya Paudel,Xiukun Wang,Hongyao Yu et al.
Sudikshya Paudel et al.
In ungulates such as pigs and sheep, blastocyst elongation is essential for implantation driven by coordinated trophoblast proliferation, cytoskeletal remodeling, and nutrient signaling. L-arginine (Arg), a conditionally essential amino aci...
Feasibility of an AI System for Follicle Quantification and Spindle Localization [0.03%]
基于人工智能的卵泡计数和纺锤体定位系统可行性研究
Weidong Li,Ning Wang,Haina Xu et al.
Weidong Li et al.
Molecular Pathogenesis of Ovarian Endometrioma: Mechanistic Insights and Therapeutic Implications [0.03%]
卵巢子宫内膜异位囊肿的分子发病机制：机制见解和治疗意义
Siyu Xia,Songyu Huang,Jiangpeng Wu et al.
Siyu Xia et al.
Ovarian endometrioma (OMA), the most prevalent and clinically consequential subtype of endometriosis, represents a chronic inflammatory disorder characterized by ectopic endometrial-like lesions. This condition manifests as progressive dysm...