SPEM2 deficiency disrupts spermiation leading to oligoasthenoteratozoospermia and male infertility† [0.03%]
Yong Li,Wenqing Lu,Lanlan Meng et al.
Yong Li et al.
Oligoasthenoteratozoospermia (OAT) is a prevalent phenotype among infertile males, yet its underlying genetic etiology remains largely undefined. In this study, we found Spem2 deficiency did not affect the development of spermatogenic cells...
Interleukin-6 and Leukemia Inhibitory Factor Differentially Modify Embryonic Disk Composition in Post Hatching Bovine Embryos† [0.03%]
Mary A Oliver,Vitor R G Mercadante,Alan D Ealy
Mary A Oliver
Proper formation of the embryonic disk is essential for pregnancy survival. This study examined whether supplementing interleukin-6 (IL6) or leukemia inhibitory factor (LIF) influence epiblast (EPI) and hypoblast (HYPO) development as well ...
Establishment of a germline cell-containing ovarian cell line capable of oocyte generation in vitro from sterlet Acipenser ruthenus† [0.03%]
Ai Sun,Hua Zhu,Tian Dong et al.
Ai Sun et al.
Sturgeons (order Acipenseriformes) represent one of the most ancient lineages of Actinopterygii. Presently, most sturgeon species are classified as critically endangered. In this study, a novel ovarian cell line which contained germline cel...
Nanoscale 3D Anatomy of the Western Flower Thrips Reproductive System Revealed by Volume Electron Microscopy: Extreme Miniaturization and Evolutionary Adaptations for Pest Fecundity [0.03%]
Guan Wang,Jian-Sheng Guo,Dan-Ting Li et al.
Guan Wang et al.
Frankliniella occidentalis (western flower thrips, WFT) is a globally destructive pest causing major crop losses via oviposition, feeding, and plant virus transmission. Previous work has focused on its reproductive physiology and behavior, ...
Kanako Hayashi,James A MacLean nd
Kanako Hayashi
Endocrine-disrupting chemicals (EDCs) are a global concern for human health and the environment. EDCs include plasticizers, pharmaceutical agents, industrial chemicals, fungicides, and pesticides. Thus, EDC exposure is a manmade consequence...
Derivation of primed sheep embryonic stem cells and conversion to an intermediate naïve-like state [0.03%]
山羊胚胎干细胞的建系及获得类似原始态干细胞性质的方法研究
T S Shyamkumar,Manuel A Vasquez-Hidalgo,Viju V Pillai
T S Shyamkumar
Embryonic stem cells (ESCs) derived from the inner cell mass of embryos possess unlimited self-renewal and pluripotency, offering a powerful system to study early development and enable genetic and biotechnological innovation. Although seve...
cAMP signaling in the placenta: a pivotal determinant of trophoblast fate and pregnancy outcomes [0.03%]
胎盘中的cAMP信号：合体细胞命运和妊娠结局的关键决定因素
Enoch Appiah Adu-Gyamfi,Daniel Neubauer
Enoch Appiah Adu-Gyamfi
Cyclic adenosine monophosphate (cAMP) signaling is a crucial pathway which regulates a myriad of physiological processes. cAMP is synthesized by adenylyl cyclases and then degraded by phosphodiesterases (PDEs). This intricate interplay of s...
Strain- and lineage-specific regulation of lipid droplet metabolism in the mouse blastocyst† [0.03%]
小鼠囊胚中应变和品系特异性脂滴代谢调控
Dominika Żbikowska,Abdul Majid Khan,Marta Marlena Ziętek et al.
Dominika Żbikowska et al.
Lipid droplets (LDs) are multifunctional organelles that serve as reservoirs of fatty acids, which act as substrates for β-oxidation and ATP synthesis during mammalian preimplantation development. However, the genetic and lineage-specific ...
High-Resolution Untargeted Metabolomics Reveals Altered Lysophosphatidylcholine, Palmitoleic Acid, Triglycerides and Isopulegone Caffeate Associated with Ovarian Injury in BTBR ob/ob Mice† [0.03%]
高分辨率非靶向代谢组学揭示卵泡损伤小鼠模型中溶血磷脂酰胆碱、棕榈油酸、甘油三酯和异紫花前胡素的改变
Yan Rong,Jiyun Chang,Zhuo Chen et al.
Yan Rong et al.
Diabetes mellitus adversely affects female reproductive health, leading to ovarian dysfunction and infertility. In this study, we investigated metabolic alterations in the ovaries of BTBR ob/ob mice, a well-established type 2 diabetes melli...
Estradiol-17β, a key embryonic signal, regulates gene expression and cellular functions in the porcine trophoblast† [0.03%]
雌二醇-17β，一个关键的胚胎信号，调节猪滋养层细胞基因表达和细胞功能
Ewelina Goryszewska-Szczurek,Agnieszka Waclawik
Ewelina Goryszewska-Szczurek
Early pregnancy is a highly coordinated process requiring precise embryo-maternal communication. Estradiol-17β (E2) is considered the primary conceptus-derived signal responsible for the maternal recognition of pregnancy in pigs. Successfu...